Encino, CALIFORNIA5 Active Studies

Major Depressive Disorder Clinical Trials in Encino, CALIFORNIA

Find 5 actively recruiting major depressive disorder clinical trials in Encino, CALIFORNIA. Connect with local research sites and explore new treatment options.

5
Active Trials
5
Sponsors
2,046
Enrolling

Recruiting Major Depressive Disorder Studies in Encino

RecruitingEncino, CALIFORNIANCT06559306

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

The purpose of this study is to know how well seltorexant works, and also to evaluate safety and maintenance effect of seltorexant compared with placebo as an adjunctive therapy to an antidepressant i...

752 participants
Janssen Research & Development, LLC
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RecruitingEncino, CALIFORNIANCT05711940

Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD

Efficacy, Safety, and Tolerability of two administrations of COMP360 in participants with treatment-resistant depression (TRD)...

568 participants
COMPASS Pathways
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RecruitingEncino, CALIFORNIANCT06058013

Study to Assess the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive Disorder

This is a randomized, double-blind, placebo-controlled, multicenter study to evaluate the effects of NMRA-335140 (formerly BTRX-335140) on symptoms of depression in participants with Major Depressive ...

332 participants
Neumora Therapeutics, Inc.
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RecruitingEncino, CALIFORNIANCT06633016

Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)

The goal of this clinical trial is to learn if ABX-002 added to an existing antidepressant treatment will benefit depression symptoms in adults with moderate to severe major depressive disorder who ha...

230 participants
Autobahn Therapeutics, Inc.
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RecruitingEncino, CALIFORNIANCT06547489

GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder

The goal of this clinical trial is to learn if GATE-251 works to treat depression in adults. It will also learn about the safety of GATE-251. The main questions it aims to answer are: Does GATE-251 r...

164 participants
Syndeio Biosciences, Inc
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About Major Depressive Disorder Clinical Trials in Encino

Major depressive disorder (MDD) is a severe form of depression characterized by persistent sadness, loss of interest, and impaired daily functioning. Treatment-resistant depression (TRD) affects patients who do not respond to standard therapies. Novel treatments like ketamine, psilocybin, and neuromodulation are being studied.

There are currently 5 major depressive disorder clinical trials recruiting participants in Encino, CALIFORNIA. These studies are seeking a combined 2,046 participants. Research is being sponsored by Janssen Research & Development, LLC, COMPASS Pathways, Neumora Therapeutics, Inc. and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Major Depressive Disorder Clinical Trials in Encino — FAQ

Are there major depressive disorder clinical trials in Encino?

Yes, there are 5 major depressive disorder clinical trials currently recruiting in Encino, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Encino?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Encino research site will contact you about next steps.

Are clinical trials in Encino free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Encino studies also compensate for your time and travel.

What major depressive disorder treatments are being tested?

The 5 active trials in Encino are testing new therapies including novel drugs, biologics, and treatment approaches for major depressive disorder.

Data updated March 2, 2026 from ClinicalTrials.gov