12 Lung Cancer Clinical Trials in Fountain Valley, CA (2026)

Q: How do I join a clinical trial in Fountain Valley?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Fountain Valley research site will contact you.

Recruiting Lung Cancer Studies in Fountain Valley

NCT05236114Recruiting

GEMINI-NSCLC: NSCLC Biomarker Study

GEMINI NSCLC Study is a non-interventional study that will be collecting clinical and molecular health information from patients with NSCLC who will receive longitudinal blood collection in addition t...

Fountain Valley, CA1,200 participantsTempus AI

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NCT05211895Recruiting

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

This is a Phase III, randomised, double-blind, placebo-controlled, multicentre, international study assessing the efficacy and safety of durvalumab (MEDI4736) and domvanalimab (AB154) compared with du...

Fountain Valley, CAPHASE3860 participantsAstraZeneca

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NCT07361510Recruiting

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

The purpose of this study is to evaluate the efficacy of Pumitamig versus Pembrolizumab in participants with previously untreated advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%....

Fountain Valley, CAPHASE3750 participantsBristol-Myers Squibb

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NCT06417814Recruiting

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

This study will assess the effect of Dato-DXd in combination with osimertinib or Dato-DXd monotherapy versus platinum-based doublet chemotherapy in terms of progression-free survival (PFS)....

Fountain Valley, CAPHASE3744 participantsAstraZeneca

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NCT06899126Recruiting

Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer

This clinical trial is designed to assess the efficacy and safety of trastuzumab deruxtecan (T-DXd; Enhertu®) in combination with pembrolizumab versus platinum-based chemotherapy in combination with p...

Fountain Valley, CAPHASE3686 participantsDaiichi Sankyo

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NCT06357533Recruiting

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

The purpose of this study is to evaluate efficacy and safety of Dato-DXd in combination with rilvegostomig or rilvegostomig monotherapy compared with pembrolizumab monotherapy as a first line therapy ...

Fountain Valley, CAPHASE3675 participantsAstraZeneca

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NCT04613596Recruiting

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

The Phase 2 portion of this study evaluates the efficacy and safety of MRTX849 monotherapy and in combination with pembrolizumab in cohorts of patients with advanced NSCLC with KRAS G12C mutation and ...

Fountain Valley, CAPHASE2626 participantsMirati Therapeutics Inc.

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NCT07217301Recruiting

A Study Comparing TAK-928 With Docetaxel in Adults With Non-Small Cell Lung Cancer

Lung cancer is one of the most common forms of cancer. One common type is non-small cell lung cancer (NSCLC). NSCLC happens when abnormal cells in the lungs grow too fast. This can stop the lungs from...

Fountain Valley, CAPHASE3600 participantsTakeda

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NCT06350097Recruiting

Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

The purpose of this study is to evaluate efficacy and safety of osimertinib (tablet) in combination with Dato-DXd (i.v. infusion) compared with osimertinib (tablet) monotherapyas a first-line therapy ...

Fountain Valley, CAPHASE3582 participantsAstraZeneca

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NCT06745908Recruiting

ResQ201A: Clinical Trial Of N-803 Plus TISLELIZUMAB And DOCETAXEL Versus DOCETAXEL Monotherapy In Participants With Advanced Or Metastatic Non-Small Cell Lung Cancer

This is a randomized, open-label, phase 3 clinical trial to compare the efficacy and safety of N-803 plus tislelizumab and docetaxel (experimental arm) versus docetaxel monotherapy (control arm). Enro...

Fountain Valley, CAPHASE3507 participantsImmunityBio, Inc.

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NCT07288177Recruiting

Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer

This Phase 2 study will be conducted in different countries around the world with up to about 240 participants. The purpose of this study is to evaluate how well Rina-S works against lung cancer. Th...

Fountain Valley, CAPHASE2240 participantsGenmab

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NCT05456256Recruiting

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

The goal of this clinical trial is to determine clinical advantages for LP-300 in combination with carboplatin and pemetrexed in the never smoker patient population. The primary objectives of this stu...

Fountain Valley, CAPHASE290 participantsLantern Pharma Inc.

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About Lung Cancer Clinical Trials in Fountain Valley

Lung cancer is the leading cause of cancer death worldwide, starting in the cells of the lungs. The two main types are non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Treatments include surgery, chemotherapy, radiation, immunotherapy, and targeted drugs.

There are currently 12 lung cancer clinical trials recruiting participants in Fountain Valley, CA. These studies are seeking a combined 7,560 participants. Research is being sponsored by Tempus AI, AstraZeneca, Bristol-Myers Squibb and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Lung Cancer Clinical Trials in Fountain Valley — FAQ

Are there lung cancer clinical trials in Fountain Valley?

Yes, there are 12 lung cancer clinical trials currently recruiting in Fountain Valley, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Fountain Valley?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Fountain Valley research site will contact you about next steps.

Are clinical trials in Fountain Valley free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Fountain Valley studies also compensate for your time and travel.

What lung cancer treatments are being tested?

The 12 active trials in Fountain Valley are testing new therapies including novel drugs, biologics, and treatment approaches for lung cancer.

Data updated July 17, 2026 from ClinicalTrials.gov