Fountain Valley, CA8 Active Studies

Breast Cancer Clinical Trials in Fountain Valley, CA

Find 8 actively recruiting breast cancer clinical trials in Fountain Valley, CA. Connect with local research sites and explore new treatment options.

8
Active Trials
6
Sponsors
13,373
Enrolling

Recruiting Breast Cancer Studies in Fountain Valley

RecruitingFountain Valley, CANCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

This is a Phase III open-label study to assess if camizestrant improves outcomes compared to standard adjuvant endocrine therapy for patients with ER+/HER2- early breast cancer with intermediate-high ...

5,500 participants
AstraZeneca
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RecruitingFountain Valley, CANCT05774951

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

This is a Phase III open-label study to assess if camizestrant improves outcomes compared to standard endocrine therapy in patients with ER+/HER2 - early breast cancer with intermediate or high risk f...

4,300 participants
AstraZeneca
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RecruitingFountain Valley, CANCT05633654

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surgery, is effective and safe compared to the treatmen...

1,514 participants
Gilead Sciences
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RecruitingFountain Valley, CANCT04862663

Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

A Phase Ib/III Open-label, Randomised Study of Capivasertib plus CDK4/6 Inhibitors and Fulvestrant versus CDK4/6 Inhibitors and Fulvestrant in Hormone Receptor-Positive and Human Epidermal Growth Fact...

895 participants
AstraZeneca
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RecruitingFountain Valley, CANCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

This phase 3 clinical trial compares the safety and efficacy of palazestrant (OP-1250) to the standard-of-care options of fulvestrant or an aromatase inhibitor in women and men with breast cancer whos...

510 participants
Olema Pharmaceuticals, Inc.
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RecruitingFountain Valley, CANCT06072612

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

This is a multicenter randomized, open label study to evaluate overall survival with the Bria-IMT regimen in combination with Checkpoint Inhibitor \[Retifanlimab\], versus Treatment of Patients'/Physi...

404 participants
BriaCell Therapeutics Corporation
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RecruitingFountain Valley, CANCT06369285

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

PUMA-ALI-1201 is a randomized, dose optimization, multicenter, Phase 2 study of alisertib administered in combination with endocrine therapy in participants with pathology-confirmed HR-positive/HER2-n...

150 participants
Puma Biotechnology, Inc.
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RecruitingFountain Valley, CANCT06966453

A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer

The purpose of this clinical study is to learn about the safety and effects of the study medicine (called disitamab vedotin) for the possible treatment of people with breast cancer that is hard to tre...

100 participants
Pfizer
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About Breast Cancer Clinical Trials in Fountain Valley

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 8 breast cancer clinical trials recruiting participants in Fountain Valley, CA. These studies are seeking a combined 13,373 participants. Research is being sponsored by AstraZeneca, Gilead Sciences, Olema Pharmaceuticals, Inc. and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in Fountain Valley — FAQ

Are there breast cancer clinical trials in Fountain Valley?

Yes, there are 8 breast cancer clinical trials currently recruiting in Fountain Valley, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Fountain Valley?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Fountain Valley research site will contact you about next steps.

Are clinical trials in Fountain Valley free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Fountain Valley studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 8 active trials in Fountain Valley are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated March 2, 2026 from ClinicalTrials.gov