11 Type 1 Diabetes Clinical Trials in Gainesville, FL (2026)

Q: How do I join a clinical trial in Gainesville?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Gainesville research site will contact you.

Recruiting Type 1 Diabetes Studies in Gainesville

NCT05899439Recruiting

Immune Function and the Progression to T1D

To elucidate the mechanisms by which type 1 diabetes-associated genes; IFIH1, TYK2, IKZF4, as well as total genetic risk, impart functional immunoregulatory abnormalities that result in expansion of s...

Gainesville, FL2,800 participantsUniversity of Florida

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NCT07864168Recruiting

Evaluation of MiniMed Next Generation Extended Wear Sensors and Algorithm in Patients With Type 1 and Type 2 Diabetes

This study will collect sensor data in subjects with T1D or T2D, 2-80 years of age....

Gainesville, FLNA1,500 participantsMedtronic MiniMed, Inc.

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NCT07088068Recruiting

A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

This is a multicenter, randomized, double-blind, parallel, placebo-controlled Phase 3, 2-arm study for treatment. The purpose of this study is to measure change in glycemic control and prandial insul...

Gainesville, FLPHASE3723 participantsSanofi

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NCT06481904Recruiting

Registry for Stage 2 Type 1 Diabetes

Stage 2 Type 1 Diabates (T1D) is an early stage of T1D characterized by dysglycemia but not yet leading to clinical symptoms. Progression of the disease to Stage 3 (clinical T1D), leads to overt hyper...

Gainesville, FL200 participantsSanofi

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NCT07187531Recruiting

SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes

This is a Phase 2b, investigator- and participant-blinded, placebo-controlled, parallel-arm study to evaluate the efficacy, safety and tolerability of SAB 142 in patients with Stage 3 New Onset of Typ...

Gainesville, FLPHASE2159 participantsSAb Biotherapeutics, Inc.

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NCT07061574Recruiting

A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes

This multi-center randomized controlled trial will assess the safety and efficacy of ATG followed by either adalimumab or verapamil in preserving insulin secretion 2 years from randomization in person...

Gainesville, FLPHASE1120 participantsCity of Hope Medical Center

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NCT06783309Recruiting

CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

This study is a Phase 1b/2a First-in-Human (FIH) clinical trial to assess the safety, tolerability, pharmacodynamics (PD), and efficacy of multiple ascending doses of CNP-103. The approximately 208-da...

Gainesville, FLPHASE172 participantsCOUR Pharmaceutical Development Company, Inc.

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NCT07142252Recruiting

Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

This Phase 2 study is a 2-arm, multi-center, double-masked (masking of the participant, care provider and investigator), placebo-controlled, 2:1 randomized trial design in new onset T1D participants (...

Gainesville, FLPHASE266 participantsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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NCT07216391Recruiting

Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG

This is a 2-arm, multi-center, open label study to learn if ATG works the same or better than teplizumab in delaying or preventing Stage 3 Type 1 diabetes. Participants will be administered either 2 i...

Gainesville, FLPHASE260 participantsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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NCT06455319Recruiting

Precision Administration of Anti-thymocyte Globulin With or Without Verapamil

T cell directed therapy, anti-thymocyte globulin (ATG), in low doses, has been shown to lower HbA1c and preserve endogenous insulin production (measured by C-peptide) in individuals with recently diag...

Gainesville, FLPHASE260 participantsUniversity of Florida

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NCT06919354Recruiting

A Study of GNTI-122 in Adults Recently Diagnosed With T1D

This is a 78-week single arm, multi-center, Phase 1 study to evaluate the safety, tolerability, cellular kinetics, and biomarker changes in C-peptide over time of GNTI-122, an investigational cell the...

Gainesville, FLPHASE116 participantsGentiBio, Inc

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About Type 1 Diabetes Clinical Trials in Gainesville

Type 1 diabetes is an autoimmune condition where the immune system destroys insulin-producing beta cells in the pancreas. It typically develops in childhood or young adulthood and requires lifelong insulin therapy. Research is exploring artificial pancreas systems, immunotherapy, and beta cell replacement.

There are currently 11 type 1 diabetes clinical trials recruiting participants in Gainesville, FL. These studies are seeking a combined 5,776 participants. Research is being sponsored by University of Florida, Medtronic MiniMed, Inc., Sanofi and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Type 1 Diabetes Clinical Trials in Gainesville — FAQ

Are there type 1 diabetes clinical trials in Gainesville?

Yes, there are 11 type 1 diabetes clinical trials currently recruiting in Gainesville, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Gainesville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Gainesville research site will contact you about next steps.

Are clinical trials in Gainesville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Gainesville studies also compensate for your time and travel.

What type 1 diabetes treatments are being tested?

The 11 active trials in Gainesville are testing new therapies including novel drugs, biologics, and treatment approaches for type 1 diabetes.

Data updated October 19, 2026 from ClinicalTrials.gov