Gainesville, FLORIDA5 Active Studies

Spinal Muscular Atrophy Clinical Trials in Gainesville, FLORIDA

Find 5 actively recruiting spinal muscular atrophy clinical trials in Gainesville, FLORIDA. Connect with local research sites and explore new treatment options.

5
Active Trials
4
Sponsors
1,290
Enrolling

Recruiting Spinal Muscular Atrophy Studies in Gainesville

RecruitingGainesville, FLORIDANCT06875310

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

This is a trial to evaluate the efficacy, safety, and tolerability of adagrasib plus pembrolizumab plus platinum-doublet chemotherapy versus placebo plus pembrolizumab plus platinum-doublet chemothera...

630 participants
Mirati Therapeutics Inc.
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RecruitingGainesville, FLORIDANCT06211036

Study Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) Following Platinum, Etoposide and Durvalumab

The primary objective of this study is to compare the efficacy of tarlatamab plus durvalumab with durvalumab alone on prolonging overall survival (OS)....

550 participants
Amgen
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RecruitingGainesville, FLORIDANCT05794139

Safety and Efficacy of NMD670 in Ambulatory Adult Patients With Type 3 Spinal Muscular Atrophy

The purpose of this study is to evaluate the efficacy, safety, tolerability and pharmacokinetics of NMD670 in the treatment of ambulatory adults with spinal muscular atrophy type 3...

54 participants
NMD Pharma A/S
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RecruitingGainesville, FLORIDANCT05861986

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy

This is an open-label, single-arm, multicenter clinical study to evaluate the effectiveness and safety of risdiplam administered as an early intervention in pediatric participants with spinal muscular...

28 participants
Hoffmann-La Roche
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RecruitingGainesville, FLORIDANCT05861999

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy

This is an open-label, single-arm, multicenter clinical study to evaluate the effectiveness and safety of risdiplam administered in pediatric participants with SMA and 2 SMN2 copies who previously rec...

28 participants
Hoffmann-La Roche
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About Spinal Muscular Atrophy Clinical Trials in Gainesville

Spinal muscular atrophy (SMA) is a genetic neuromuscular disorder that causes loss of motor neurons, leading to progressive muscle weakness and atrophy. It is the leading genetic cause of infant death. Revolutionary gene therapies and SMN-enhancing drugs have transformed treatment.

There are currently 5 spinal muscular atrophy clinical trials recruiting participants in Gainesville, FLORIDA. These studies are seeking a combined 1,290 participants. Research is being sponsored by Mirati Therapeutics Inc., Amgen, NMD Pharma A/S and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Spinal Muscular Atrophy Clinical Trials in Gainesville — FAQ

Are there spinal muscular atrophy clinical trials in Gainesville?

Yes, there are 5 spinal muscular atrophy clinical trials currently recruiting in Gainesville, FLORIDA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Gainesville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Gainesville research site will contact you about next steps.

Are clinical trials in Gainesville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Gainesville studies also compensate for your time and travel.

What spinal muscular atrophy treatments are being tested?

The 5 active trials in Gainesville are testing new therapies including novel drugs, biologics, and treatment approaches for spinal muscular atrophy.

Data updated March 2, 2026 from ClinicalTrials.gov