Garden Grove, CALIFORNIA5 Active Studies

Depression Clinical Trials in Garden Grove, CALIFORNIA

Find 5 actively recruiting depression clinical trials in Garden Grove, CALIFORNIA. Connect with local research sites and explore new treatment options.

5
Active Trials
4
Sponsors
1,958
Enrolling

Recruiting Depression Studies in Garden Grove

RecruitingGarden Grove, CALIFORNIANCT06029439

Study to Assess the Safety and Effectiveness of NMRA-335140-501

This is a 52-week open-label extension (OLE) study that will evaluate the safety, tolerability, and effectiveness of NMRA-335140 in participants with major depressive disorder (MDD). Participants who ...

1,000 participants
Neumora Therapeutics, Inc.
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RecruitingGarden Grove, CALIFORNIANCT07065240

A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

This is a randomized, parallel-group, double-blind, placebo-controlled, monotherapy study to evaluate the efficacy, safety, and tolerability of SPT-300 (GlyphAllo) in adults with major depressive diso...

360 participants
Seaport Therapeutics
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RecruitingGarden Grove, CALIFORNIANCT06058013

Study to Assess the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive Disorder

This is a randomized, double-blind, placebo-controlled, multicenter study to evaluate the effects of NMRA-335140 (formerly BTRX-335140) on symptoms of depression in participants with Major Depressive ...

332 participants
Neumora Therapeutics, Inc.
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RecruitingGarden Grove, CALIFORNIANCT06524830

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

This Phase 2 study (protocol number VLS-01-203) will determine the efficacy, safety, and tolerability of short-term treatment with a VLS-01 transmucosal buccal film (VLS-01-BU) in patients with treatm...

142 participants
atai Therapeutics, Inc.
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RecruitingGarden Grove, CALIFORNIANCT06785012

A Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive Disorder

The purpose of this study is to evaluate how well JNJ-89495120 works (anti-depressant effects) and how well it is tolerated as compared to placebo on reducing the symptoms of depression in participant...

124 participants
Janssen Research & Development, LLC
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About Depression Clinical Trials in Garden Grove

Depression (major depressive disorder) is a common and serious mood disorder that negatively affects how you feel, think, and handle daily activities. It affects over 280 million people globally. Treatment includes psychotherapy, antidepressant medications, and brain stimulation therapies.

There are currently 5 depression clinical trials recruiting participants in Garden Grove, CALIFORNIA. These studies are seeking a combined 1,958 participants. Research is being sponsored by Neumora Therapeutics, Inc., Seaport Therapeutics, atai Therapeutics, Inc. and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Depression Clinical Trials in Garden Grove — FAQ

Are there depression clinical trials in Garden Grove?

Yes, there are 5 depression clinical trials currently recruiting in Garden Grove, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Garden Grove?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Garden Grove research site will contact you about next steps.

Are clinical trials in Garden Grove free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Garden Grove studies also compensate for your time and travel.

What depression treatments are being tested?

The 5 active trials in Garden Grove are testing new therapies including novel drugs, biologics, and treatment approaches for depression.

Data updated March 2, 2026 from ClinicalTrials.gov