Glendale, AZ8 Active Studies

Depression Clinical Trials in Glendale, AZ

Find 8 actively recruiting depression clinical trials in Glendale, AZ. Connect with local research sites and explore new treatment options.

8
Active Trials
8
Sponsors
3,450
Enrolling

Recruiting Depression Studies in Glendale

RecruitingGlendale, AZNCT06029439

Study to Assess the Safety and Effectiveness of NMRA-335140-501

This is a 52-week open-label extension (OLE) study that will evaluate the safety, tolerability, and effectiveness of NMRA-335140 in participants with major depressive disorder (MDD). Participants who ...

1,000 participants
Neumora Therapeutics, Inc.
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RecruitingGlendale, AZNCT06559306

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

The purpose of this study is to know how well seltorexant works, and also to evaluate safety and maintenance effect of seltorexant compared with placebo as an adjunctive therapy to an antidepressant i...

752 participants
Janssen Research & Development, LLC
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RecruitingGlendale, AZNCT06775379

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

X-NOVA2 is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of azetukalner as a monotherapy in adult participants ...

450 participants
Xenon Pharmaceuticals Inc.
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RecruitingGlendale, AZNCT07065240

A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

This is a randomized, parallel-group, double-blind, placebo-controlled, monotherapy study to evaluate the efficacy, safety, and tolerability of SPT-300 (GlyphAllo) in adults with major depressive diso...

360 participants
Seaport Therapeutics
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RecruitingGlendale, AZNCT05922878

Study of ALTO-300 in MDD

The purpose of this study is to determine efficacy differences between ALTO-300 and placebo, used adjunctively to an antidepressant, related to patient characteristics....

321 participants
Alto Neuroscience
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RecruitingGlendale, AZNCT06633016

Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)

The goal of this clinical trial is to learn if ABX-002 added to an existing antidepressant treatment will benefit depression symptoms in adults with moderate to severe major depressive disorder who ha...

230 participants
Autobahn Therapeutics, Inc.
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RecruitingGlendale, AZNCT06836063

Study to Evaluate Efficacy and Safety of Ropanicant in MDD Patients

The primary objective is to evaluate the efficacy of Ropanicant at two different dosage levels compared to placebo in patients with Major Depressive Disorder (MDD)....

195 participants
Suven Life Sciences Limited
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RecruitingGlendale, AZNCT06524830

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

This Phase 2 study (protocol number VLS-01-203) will determine the efficacy, safety, and tolerability of short-term treatment with a VLS-01 transmucosal buccal film (VLS-01-BU) in patients with treatm...

142 participants
atai Therapeutics, Inc.
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About Depression Clinical Trials in Glendale

Depression (major depressive disorder) is a common and serious mood disorder that negatively affects how you feel, think, and handle daily activities. It affects over 280 million people globally. Treatment includes psychotherapy, antidepressant medications, and brain stimulation therapies.

There are currently 8 depression clinical trials recruiting participants in Glendale, AZ. These studies are seeking a combined 3,450 participants. Research is being sponsored by Neumora Therapeutics, Inc., Janssen Research & Development, LLC, Xenon Pharmaceuticals Inc. and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Depression Clinical Trials in Glendale — FAQ

Are there depression clinical trials in Glendale?

Yes, there are 8 depression clinical trials currently recruiting in Glendale, AZ. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Glendale?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Glendale research site will contact you about next steps.

Are clinical trials in Glendale free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Glendale studies also compensate for your time and travel.

What depression treatments are being tested?

The 8 active trials in Glendale are testing new therapies including novel drugs, biologics, and treatment approaches for depression.

Data updated March 2, 2026 from ClinicalTrials.gov