Grand Rapids, MICHIGAN19 Active Studies

Alzheimers Disease Clinical Trials in Grand Rapids, MICHIGAN

Find 19 actively recruiting alzheimers disease clinical trials in Grand Rapids, MICHIGAN. Connect with local research sites and explore new treatment options.

19
Active Trials
17
Sponsors
5,652
Enrolling

Recruiting Alzheimers Disease Studies in Grand Rapids

RecruitingGrand Rapids, MICHIGANNCT04626635

A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers

This study is researching an investigational drug called REGN7075 by itself and in combination with cemiplimab with or without chemotherapy. The study is focused on patients with certain solid tumors ...

933 participants
Regeneron Pharmaceuticals
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RecruitingGrand Rapids, MICHIGANNCT05768139

First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

Study STX-478-101 is a multipart, open-label, phase 1/2 study evaluating the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of STX-478 (LY4064809) in participants with...

720 participants
Eli Lilly and Company
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RecruitingGrand Rapids, MICHIGANNCT05844982

Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 Mg) Intravitreal Implants Vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

This randomized controlled trial will evaluate the effect of intravitreal faricimab or fluocinolone acetonide (FAc) intravitreal implant compared with observation on long-term visual acuity following ...

600 participants
Jaeb Center for Health Research
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RecruitingGrand Rapids, MICHIGANNCT05489211

Study of Dato-Dxd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

TROPION-PanTumor03 will investigate the safety, tolerability, and anti-tumour activity of Datopotamab Deruxtecan (Dato-DXd) as Monotherapy and in Combination with Anticancer Agents in Patients with Ad...

582 participants
AstraZeneca
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RecruitingGrand Rapids, MICHIGANNCT07070232

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

This study will evaluate the safety, efficacy, optimal dose, and pharmacokinetics (PK) of BNT326 as monotherapy (Part 1) and as combination treatment with immunotherapeutic agents (Part 2) in particip...

550 participants
BioNTech SE
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RecruitingGrand Rapids, MICHIGANNCT07197827

A Study of YL242 in Subjects With Advanced Solid Tumors

This is a multicenter, open-label study to evaluate the safety and tolerability of YL242 monotherapy and combination in participants with advanced solid malignant tumors....

424 participants
MediLink Therapeutics (Suzhou) Co., Ltd.
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RecruitingGrand Rapids, MICHIGANNCT06730750

A Study of BMS-986490 With or Without Bevacizumab in Advanced Solid Tumors

This is a study of BMS-986490 as a monotherapy and in combination with bevacizumab in participants with select advanced solid tumors known to express CEACAM5....

360 participants
Bristol-Myers Squibb
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RecruitingGrand Rapids, MICHIGANNCT06685068

A Phase 1/2 Study of GEN1286 in Patients With Advanced Solid Tumors

The purpose of this trial is to evaluate the safety, tolerability, pharmacokinetics (PK), anti-tumor activity and immunogenic potential of GEN1286 in participants with advanced solid tumors. This tri...

260 participants
Genmab
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RecruitingGrand Rapids, MICHIGANNCT04046497

Artificial Intelligence to Measure Adherence to Oral Medication

The aims of this project is to use an artificial intelligence (AI) smartphone app to provide support for medication adherence by patients with first episode psychosis....

200 participants
Northwell Health
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RecruitingGrand Rapids, MICHIGANNCT05985655

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

The primary purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK) and anti-tumor activity of GTAEXS617-001 in participants with advanced solid tumors....

165 participants
Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.
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RecruitingGrand Rapids, MICHIGANNCT07023731

A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation

This is a study to evaluate the safety and potential anti-tumor activity of an investigational agent called ARV-806 in Adults with Advanced Cancer having a specific KRAS mutation. This is an open-labe...

159 participants
Arvinas Inc.
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RecruitingGrand Rapids, MICHIGANNCT06413680

A First-In Human (FIH) Trial to Find Out if REGN10597 is Safe and How Well it Works for Adult Participants With Advanced Solid Organ Malignancies

This study is researching an experimental drug called REGN10597 (called "study drug"). The study is focused on patients with certain solid tumors that are in an advanced stage. The aim of the study i...

150 participants
Regeneron Pharmaceuticals
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RecruitingGrand Rapids, MICHIGANNCT06469944

Substudy 06C: A Study of Sacituzumab Tirumotecan (MK-2870) With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

This is a phase 1/2, multicenter, open-label umbrella platform study that will evaluate the safety and tolerability of sacituzumab tirumotecan with pembrolizumab and fluoropyrimidine chemotherapy for ...

130 participants
Merck Sharp & Dohme LLC
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RecruitingGrand Rapids, MICHIGANNCT05902988

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

This is a first-in-human phase I/II study to examine the safety, tolerability and preliminary efficacy of VLS-1488 in subjects with advanced cancers....

120 participants
Volastra Therapeutics, Inc.
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RecruitingGrand Rapids, MICHIGANNCT06833008

A Study to Assess a New Medicine Called IPN01195 When Administered Alone in Adults With Advanced Solid Tumours

The purpose of this study is to determine the appropriate dosage, safety and effectiveness of a new study drug IPN01195 in adults with advanced solid tumours. The participants in this study will have...

85 participants
Ipsen
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RecruitingGrand Rapids, MICHIGANNCT05552755

Evaluate REC-4881 in Patients With FAP

This is a multicenter, two-part trial in participants with Familial Adenomatous Polyposis (FAP)....

67 participants
Recursion Pharmaceuticals Inc.
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RecruitingGrand Rapids, MICHIGANNCT07115043

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors...

60 participants
AstraZeneca
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RecruitingGrand Rapids, MICHIGANNCT06730347

A Study of Lorigerlimab in Participants With Advanced Solid Tumors

Study CP-MGD019-03 is an open-label study of lorigerlimab in participants with platinum-resistant ovarian cancer (PROC) or clear cell gynecologic cancer (CCGC). Approximately 60 participants will be e...

60 participants
MacroGenics
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RecruitingGrand Rapids, MICHIGANNCT06943521

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

This is a First In Human (FIH), multicenter, open-label, Phase I/II study to evaluate safety, tolerability, Pharmacokinetics (PK), pharmacodynamics, and efficacy of MT-4561 in patients with advanced s...

27 participants
Mitsubishi Tanabe Pharma America Inc.
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About Alzheimers Disease Clinical Trials in Grand Rapids

Alzheimer's disease is a progressive brain disorder that destroys memory, thinking skills, and the ability to carry out daily tasks. It is the most common cause of dementia, affecting over 6.7 million Americans age 65 and older. The disease is characterized by amyloid-beta plaques and tau tangles in the brain. Recent FDA approvals of anti-amyloid antibodies like lecanemab (Leqembi) and donanemab have opened a new era of disease-modifying treatments. Clinical trials are now exploring next-generation amyloid-clearing therapies, tau-targeting treatments, anti-inflammatory approaches, and combination strategies. Early-stage patients with mild cognitive impairment or early Alzheimer's are frequently sought for enrollment, and many trials now use blood-based biomarkers for screening.

There are currently 19 alzheimers disease clinical trials recruiting participants in Grand Rapids, MICHIGAN. These studies are seeking a combined 5,652 participants. Research is being sponsored by Regeneron Pharmaceuticals, Eli Lilly and Company, Jaeb Center for Health Research and 14 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Alzheimers Disease Clinical Trials in Grand Rapids — FAQ

Are there alzheimers disease clinical trials in Grand Rapids?

Yes, there are 19 alzheimers disease clinical trials currently recruiting in Grand Rapids, MICHIGAN. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Grand Rapids?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Grand Rapids research site will contact you about next steps.

Are clinical trials in Grand Rapids free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Grand Rapids studies also compensate for your time and travel.

What alzheimers disease treatments are being tested?

The 19 active trials in Grand Rapids are testing new therapies including novel drugs, biologics, and treatment approaches for alzheimers disease.

Data updated March 2, 2026 from ClinicalTrials.gov