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Evaluate REC-4881 in Patients With FAP

(TUPELO)

Sponsored by Recursion Pharmaceuticals Inc.

Quick Self-Assessment

See if you qualify and express your interest

Preparing your pre-screening questions...

Current Status

Recruiting

Auto-verified from ClinicalTrials.gov

Verified Dec 4, 2025

Phase

Clinical Trial

Sponsor

Recursion Pharmaceuticals Inc.

Enrollment Target

67

Start Date

Jul 2023

๐Ÿ“Š
1 of 67 participants interested
1% interest

Express Your Interest Today

Interested in learning more? Complete the form below.

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Advance Medical Science

    Contribute to groundbreaking research

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel (varies by study)

  • Help Others

    Benefit future patients

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3In-person assessment if eligible
  4. 4Begin participation

About This Study

This is a multicenter, two-part trial in participants with Familial Adenomatous Polyposis (FAP).

Who Can Participate

Inclusion Criteria

Male or female and โ‰ฅ 55 years of age 2. Have provided written informed consent to participate in the study 3. Diagnosis of phenotypic classical FAP with disease involvement of the duodenum or the residual colon/rectum/pouch as the primary disease site. 4. Genetic diagnosis of FAP with APC gene mutation (Part 2 only). 5. Has undergone colectomy or subtotal colectomy 6. Spigelman Classification Stage II or higher. 7. Investigator/Participant agrees to leave polyps โ‰ค10 mm unresected during endoscopies performed at Screening and while on study 8. Have no significant cardiovascular abnormalities at Screening: 1. Left ventricular ejection fraction \>50% as determined on screening echocardiogram 2. A QT interval corrected for heart rate using the Fridericia formula (QTcF) \< 450 msec in men and \<470 msec in women. 9. Have no significant hematopoietic abnormalities at Screening: 1. White blood cell count (WBC) โ‰ฅ 3,000/mm3 (non-black populations); 2,700/mm3 (

โ“ Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility during the screening process.

Study Details

๐Ÿ“‹

Study Type

INTERVENTIONAL

๐Ÿ‘ฅ

Target Enrollment

67 participants

โšง

Gender

ALL

๐Ÿข

Sponsor

Recursion Pharmaceuticals Inc.

Study Locations

Choose your preferred location or select flexible during enrollment

ACTIVE_NOT_RECRUITING

Scottsdale

Arizona

Location available
View Scottsdale location page
WITHDRAWN

Tucson

Arizona

Location available
View Tucson location page
WITHDRAWN

San Diego

California

Location available
View San Diego location page
WITHDRAWN

Naples

Florida

Location available
View Naples location page
ACTIVE_NOT_RECRUITING

Orlando

Florida

Location available
View Orlando location page
WITHDRAWN

New Albany

Indiana

Location available
View New Albany location page
TERMINATED

Marrero

Louisiana

Location available
View Marrero location page
RECRUITING

Grand Rapids

Michigan

Location available
View Grand Rapids location page
RECRUITING

Rochester

Minnesota

Location available
View Rochester location page

๐Ÿ“ And 8 more locations available

Frequently Asked Questions

Q:What is a clinical trial?

A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.

Q:Will I be compensated?

Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.

Q:Will I receive a placebo instead of treatment?

When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.

Q:Can I leave a trial if I change my mind?

Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.

Q:How long does a clinical trial last?

Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.

Still have questions? Our study coordinators are here to help.

Ready to Make a Difference?

Express your interest in this groundbreaking clinical trial

๐Ÿ”’ Secure ยท ๐Ÿฅ Expert Care

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Looking for Familial Adenomatous Polyposis Treatment in Scottsdale?

Join others in Arizona exploring innovative treatment options through clinical research

Familial Adenomatous Polyposis Treatment Options in Scottsdale, Arizona

If you're searching for Familial Adenomatous Polyposis treatment in Scottsdale, participating in a clinical research study may provide access to innovative approaches under expert medical supervision. This study is actively recruiting participants in Scottsdale, Tucson, San Diego and surrounding areas.

Clinical trials offer participants the opportunity to receive cutting-edge treatments while contributing to medical research that may help future patients with Familial Adenomatous Polyposis. All study-related care is provided at no cost to participants.

Local Sites
3 locations in Arizona
Now Enrolling
Up to 67 participants
Quick Start
Screening available now

Why Consider a Clinical Trial for Familial Adenomatous Polyposis?

Potential Benefits

  • โœ“Access to new treatment approaches before public availability
  • โœ“Close monitoring by experienced medical professionals
  • โœ“Study-related care provided at no cost
  • โœ“Contribute to medical research for Familial Adenomatous Polyposis

What to Expect

  • โ†’Initial screening to determine eligibility
  • โ†’Regular check-ups and monitoring visits
  • โ†’Possible compensation for time and travel
  • โ†’You can withdraw at any time

Frequently Asked Questions About This Familial Adenomatous Polyposis Study

Important Clinical Trial Information

This information is provided for educational purposes and does not constitute medical advice. Clinical trial participation involves potential risks and benefits. Eligibility requirements apply and will be assessed during the screening process.

Study identifier: NCT05552755. For complete study details, visit ClinicalTrials.gov. Always consult with your healthcare provider before making decisions about your medical care or participating in clinical research.