Recruiting Esophageal Cancer Studies in Houston
Effectiveness and Performance of an Optical Biopsy Technology for Esophageal Cancer in Brazil and the United States
In a previous clinical trial in China and the United States (US), the investigators developed and validated a mobile, high-resolution microendoscope (mHRME) for screening and surveillance of esophagea...
Substudy 06C: A Study of Sacituzumab Tirumotecan (MK-2870) With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)
This is a phase 1/2, multicenter, open-label umbrella platform study that will evaluate the safety and tolerability of sacituzumab tirumotecan with pembrolizumab and fluoropyrimidine chemotherapy for ...
Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)
This is a phase 1/2 multicenter, open-label umbrella platform study that will evaluate the safety and efficacy of sacituzumab tirumotecan (MK-2870) plus paclitaxel versus ramucirumab plus paclitaxel, ...
A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer
Esophageal cancer, which has a low 5-year overall survival rate (\<20%) is increasing in incidence. Previous studies have shown that Hedgehog, AKT, and angiogenic signaling pathways are activated in a...
A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer
The purpose of this study to find out whether adding trastuzumab and pembrolizumab to standard chemotherapy is an effective treatment for resectable HER2+ esophagogastric cancer....
About Esophageal Cancer Clinical Trials in Houston
Esophageal cancer occurs in the esophagus, the tube connecting the throat to the stomach. The two main types are squamous cell carcinoma and adenocarcinoma. Treatment may include surgery, chemotherapy, radiation, and immunotherapy.
There are currently 5 esophageal cancer clinical trials recruiting participants in Houston, TX. These studies are seeking a combined 547 participants. Research is being sponsored by Baylor College of Medicine, Merck Sharp & Dohme LLC, VA Office of Research and Development and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.
Esophageal Cancer Clinical Trials in Houston — FAQ
Are there esophageal cancer clinical trials in Houston?
Yes, there are 5 esophageal cancer clinical trials currently recruiting in Houston, TX. Browse the studies on this page to find one that fits.
How do I join a clinical trial in Houston?
Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Houston research site will contact you about next steps.
Are clinical trials in Houston free?
Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Houston studies also compensate for your time and travel.
What esophageal cancer treatments are being tested?
The 5 active trials in Houston are testing new therapies including novel drugs, biologics, and treatment approaches for esophageal cancer.
Data updated March 2, 2026 from ClinicalTrials.gov