5 Myelofibrosis Clinical Trials in Houston, TX (2026)

Q: How do I join a clinical trial in Houston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Houston research site will contact you.

Recruiting Myelofibrosis Studies in Houston

NCT05280509Recruiting

Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib

This study evaluates TL-895, a potent, orally-available and highly selective irreversible tyrosine kinase inhibitor for the treatment of Myelofibrosis. Participants must have MF (PMF, Post PV MF, or P...

Houston, TX70 participantsTelios Pharma, Inc.

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NCT06517875Recruiting

Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent Myelofibrosis

The purpose of this Phase 2 study is to evaluate the efficacy and safety of momelotinib (MMB) in combination with luspatercept (LUSPA) in participants with transfusion dependence (TD) primary myelofib...

Houston, TX68 participantsGlaxoSmithKline

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NCT07128381Recruiting

Phase I/II Clinical Trial of Axatilimab, a CSF1R Monoclonal Antibody, in Combination With Ruxolitinib as Therapy for Patients With Myelofibrosis (MF) and Chronic Myelomonocytic Leukemia (CMML)

* To find the recommended dose of axatilimab given alone and in combination with ruxolitinib in patients with MF and CMML. * To learn if axatilimab given in combination with ruxolitinib can help to co...

Houston, TX66 participantsM.D. Anderson Cancer Center

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NCT05980806Recruiting

A Study of Selinexor Monotherapy in Subjects with JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia

The main purpose of this study with corresponding optional expansion is to evaluate the efficacy of selinexor in JAKi-naïve participants with myelofibrosis (MF) and moderate thrombocytopenia based on ...

Houston, TX58 participantsKaryopharm Therapeutics Inc

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NCT05423691Recruiting

Leading in MPNs Beyond Ruxolitinib in Combo With T-Regs

To assess the safety and tolerability of CK0804 as add-on therapy in participants with myelofibrosis, with suboptimal response to ruxolitinib...

Houston, TX24 participantsCellenkos, Inc.

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About Myelofibrosis Clinical Trials in Houston

Myelofibrosis is a serious bone marrow disorder that disrupts normal blood cell production, leading to extensive scarring in the bone marrow. It can cause severe anemia, weakness, and an enlarged spleen. Treatment includes JAK inhibitors, blood transfusions, and stem cell transplant.

There are currently 5 myelofibrosis clinical trials recruiting participants in Houston, TX. These studies are seeking a combined 286 participants. Research is being sponsored by Telios Pharma, Inc., GlaxoSmithKline, M.D. Anderson Cancer Center and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Myelofibrosis Clinical Trials in Houston — FAQ

Are there myelofibrosis clinical trials in Houston?

Yes, there are 5 myelofibrosis clinical trials currently recruiting in Houston, TX. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Houston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Houston research site will contact you about next steps.

Are clinical trials in Houston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Houston studies also compensate for your time and travel.

What myelofibrosis treatments are being tested?

The 5 active trials in Houston are testing new therapies including novel drugs, biologics, and treatment approaches for myelofibrosis.

Data updated July 13, 2026 from ClinicalTrials.gov