20 Osteogenesis Imperfecta Clinical Trials in Indianapolis, IN (2026)

Q: Are there osteogenesis imperfecta clinical trials in Indianapolis?

Yes, there are 20 osteogenesis imperfecta clinical trials currently recruiting in Indianapolis, IN.

Q: How do I join a clinical trial in Indianapolis?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Indianapolis research site will contact you.

Q: Are clinical trials in Indianapolis free?

Yes, clinical trial participation is always free. Study-related treatments, medical tests, and doctor visits are provided at no cost.

Recruiting Osteogenesis Imperfecta Studies in Indianapolis

NCT07135323Recruiting

AvertD Post-Approval Study

A Prospective Post-Approval Study of AvertD to Evaluate Device Performance, Prescribing Impact, and Labeling Comprehension in the Intended Use Population...

Indianapolis, IN4,000 participantsPrescient Medicine Holdings, Inc.

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NCT03328611Recruiting

MCJR Joint Replacement Clinical Outcomes Database

The purpose of this research study is to develop a database of information regarding the diagnosis, treatment, and outcome of participants who have had a joint replacement. The more information gather...

Indianapolis, IN2,000 participantsMidwest Center for Joint Replacement

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NCT06465810Recruiting

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

The MaesTTRo study aims to enroll a global cohort of patients with transthyretin (ATTR) amyloidosis to longitudinally observe the natural course of the disease and describe real-world treatment patter...

Indianapolis, IN1,850 participantsAstraZeneca

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NCT03511118Recruiting

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Over half of women in the US who are breastfeeding their infants take prescription drugs. You are being asked to participate in this study because you are breastfeeding your infant and are currently t...

Indianapolis, IN1,600 participantsDuke University

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NCT02523118Recruiting

OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages

The purpose of this observational study is to find the best measures to define how well a person with eosinophilic disorder is doing. People with EoE, EoG, EoN and EoC normally undergo endoscopy and/o...

Indianapolis, IN1,350 participantsChildren's Hospital Medical Center, Cincinnati

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NCT05750498Recruiting

A-LiNK: Improving Outcomes in Autoimmune Liver Disease

The Autoimmune Liver disease Network for Kids (A-LiNK) is a multi-institutional group with the mission to deliver the best care to kids with pediatric autoimmune liver disease (AILD). This study will...

Indianapolis, IN800 participantsChildren's Hospital Medical Center, Cincinnati

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NCT07278375Recruiting

Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome

The goal of this observational study is to learn how two medicines used in routine care-buprenorphine and morphine-affect recovery in newborns (≥36 weeks' gestation) with Neonatal Opioid Withdrawal Sy...

Indianapolis, IN796 participantsHELP for NOWS Consortium

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NCT06532877Recruiting

Telephone Support in Advanced Gastrointestinal Cancer

The goal of this clinical trial is to see if telephone support programs help patients and their family caregivers adjust to advanced gastrointestinal cancer. A new telephone counseling program that in...

Indianapolis, IN488 participantsIndiana University

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NCT05361941Recruiting

Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth In/near Infected Bone Cavities

This is a pivotal, prospective, multi-center, randomized, concurrent control, patient and assessor-blinded study with two arms: a treatment arm (where subjects will be treated with the EP Granules wit...

Indianapolis, IN204 participantsElute, Inc.

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NCT05711667Recruiting

A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

This phase III single arm trial determines whether taking prophylactic letermovir will reduce the likelihood of infection with cytomegalovirus (CMV) in children and adolescents after stem cell transpl...

Indianapolis, IN105 participantsChildren's Oncology Group

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NCT07062588Recruiting

Osteogenesis Imperfecta Trial of AGA2115 for ADUlts With COL1A1 and/or COL1A2 GeNetic Variations (IDUN)

This study will determine the effect of treatment of AGA2115 in adults with Type I, III, or IV osteogenesis imperfecta versus placebo....

Indianapolis, IN80 participantsAngitia Incorporated Limited

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NCT05435547Recruiting

Preoperative Corticosteroids in Autoimmune Thyroid Disease

This study proposes to randomize patients about to undergo surgery for their autoimmune, inflammatory thyroid disease, and determine if a short course of corticosteroids decreases the inflammation of ...

Indianapolis, IN76 participantsIndiana University

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NCT07366086Recruiting

Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis Imperfecta

The primary objective of this trial is to evaluate the safety of romosozumab in participants with osteogenesis imperfecta (OI) that have completed Study 20200105, regardless of whether they received i...

Indianapolis, IN71 participantsAmgen

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NCT07556341Recruiting

Point-of-care Ultrasound Utility in the Free Clinic Setting

The goal of this observational study is to learn about the clinical utility of point-of-care ultrasound (POCUS) in patients receiving care in a free clinic or street medicine setting in Indianapolis. ...

Indianapolis, IN50 participantsIndiana University

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NCT06250309Recruiting

Mediterranean Diet Versus Western Diet on Fatigue in Autoimmune Hepatitis Patients

This is a single-center, proof-of-concept pilot study which uses a cross-over design to compare two dietary interventions/treatments: Western Diet (WD) vs Mediterranean (MD) and impact on quality-of-l...

Indianapolis, IN48 participantsIndiana University

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NCT07012044Recruiting

A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

This phase I trial tests the safety, side effects, and best dose of ASTX727 and filgrastim for the treatment of children with high risk acute myeloid leukemia that has come back after a period of impr...

Indianapolis, IN47 participantsNational Cancer Institute (NCI)

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NCT06538558Recruiting

Study to Assess the Use of Tezampanel for Opioid Withdrawal Syndrome in Treatment-Seeking Patients With Opioid Use Disorder

This study is examining the use of Tezampanel (TZP) for treatment of Opioid Withdrawal Syndrome (OWS) in participants with Opioid Use Disorder (OUD). Participants will receive TZP or placebo (PBO) dai...

Indianapolis, IN40 participantsProniras Corporation

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NCT06247787Recruiting

A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

This phase I trial tests the safety, side effects, and best dose of imetelstat in combination with fludarabine and cytarabine in treating patients with acute myeloid leukemia (AML), myelodysplastic sy...

Indianapolis, IN36 participantsChildren's Oncology Group

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NCT04925479Recruiting

Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia

The aim of this study is to support development of asciminib in the pediatric population (1 to \<18 years) previously treated with one or more TKIs. Full extrapolation of the efficacy of asciminib fro...

Indianapolis, IN34 participantsNovartis Pharmaceuticals

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NCT06197672Recruiting

Chimeric Antigen Receptor T Cell Redirected to Target CD4 Positive Relapsed Refractory Acute Myeloid Leukemia (AML ) as a Bridge to Allogeneic Stem Cell Transplant

This study is designed as a single arm open label traditional Phase I, 3+3, study of CD4-redirected chimeric antigen receptor engineered T-cells (CD4CAR) in subjects with relapsed or refractory AML. T...

Indianapolis, IN30 participantsHuda Salman

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About Osteogenesis Imperfecta Clinical Trials in Indianapolis

Osteogenesis imperfecta is a group of genetic disorders mainly affecting the bones, causing them to break easily, often from little or no apparent cause. It is caused by defects in collagen production. Treatment includes bisphosphonates, physical therapy, and surgical rodding.

There are currently 20 osteogenesis imperfecta clinical trials recruiting participants in Indianapolis, IN. These studies are seeking a combined 13,705 participants. Research is being sponsored by Prescient Medicine Holdings, Inc., Midwest Center for Joint Replacement, AstraZeneca and 12 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Osteogenesis Imperfecta Clinical Trials in Indianapolis — FAQ

Are there osteogenesis imperfecta clinical trials in Indianapolis?

Yes, there are 20 osteogenesis imperfecta clinical trials currently recruiting in Indianapolis, IN. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Indianapolis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Indianapolis research site will contact you about next steps.

Are clinical trials in Indianapolis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Indianapolis studies also compensate for your time and travel.

What osteogenesis imperfecta treatments are being tested?

The 20 active trials in Indianapolis are testing new therapies including novel drugs, biologics, and treatment approaches for osteogenesis imperfecta.

Data updated July 13, 2026 from ClinicalTrials.gov