Indianapolis, INDIANA7 Active Studies

Spinal Muscular Atrophy Clinical Trials in Indianapolis, INDIANA

Find 7 actively recruiting spinal muscular atrophy clinical trials in Indianapolis, INDIANA. Connect with local research sites and explore new treatment options.

7
Active Trials
7
Sponsors
1,192
Enrolling

Recruiting Spinal Muscular Atrophy Studies in Indianapolis

RecruitingIndianapolis, INDIANANCT06211036

Study Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) Following Platinum, Etoposide and Durvalumab

The primary objective of this study is to compare the efficacy of tarlatamab plus durvalumab with durvalumab alone on prolonging overall survival (OS)....

550 participants
Amgen
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RecruitingIndianapolis, INDIANANCT04317534

Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

A randomized trial of adjuvant Pembrolizumab following surgical resection versus observation following surgical resection in patients with stage I non-small cell lung cancer (NSCLC) with primary tumor...

244 participants
Greg Durm, MD
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RecruitingIndianapolis, INDIANANCT05882058

DAREONâ„¢-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

This study is open to adults with small cell lung cancer and other neuroendocrine tumours. The study is in people with advanced cancer for whom previous treatment was not successful or no standard tre...

174 participants
Boehringer Ingelheim
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RecruitingIndianapolis, INDIANANCT04367311

Adjuvant Treatment With Cisplatin-based Chemotherapy Plus Concomitant Atezolizumab in Patients With Stage I (Tumors ≥ 4cm), IIA, IIB, and Select Stage III [Any T1-3 N1-2 and T4N0-2] Resected Non-small Cell Lung Cancer (NSCLC) and the Clearance of Circulating Tumor DNA (ctDNA)

The vast majority of patients with stage I (tumors ≥ 4cm), IIA, IIB (and select stage III) NSCLC are managed with upfront surgery, followed by adjuvant chemotherapy. However, relapse rates remain high...

100 participants
Nasser Hanna
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RecruitingIndianapolis, INDIANANCT04919382

Temozolomide and Atezolizumab as Second or Third Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

This phase II trial studies the effects of temozolomide and atezolizumab as second or third line treatment for patients with small cell lung cancer that has spread to other places in the body (metasta...

56 participants
Dwight Owen
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RecruitingIndianapolis, INDIANANCT05903092

MOnaliZumab in Combination With durvAlumab (MEDI4736) Plus Platinum-based chemotheRapy for First-line Treatment of Extensive Stage Small Cell Lung Cancer

The study treatment will consist of a platinum drug (carboplatin or cisplatin per investigator's choice) plus etoposide plus durvalumab plus monalizumab every 3 weeks for 4 cycles. After 4 cycles, sub...

38 participants
Hirva Mamdani
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RecruitingIndianapolis, INDIANANCT04699838

Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer

The primary objective of this single arm study is to estimate the progression free survival of previously-untreated patients with extensive stage small cell lung cancer. Patients will receive initial ...

30 participants
Muhammad Furqan
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About Spinal Muscular Atrophy Clinical Trials in Indianapolis

Spinal muscular atrophy (SMA) is a genetic neuromuscular disorder that causes loss of motor neurons, leading to progressive muscle weakness and atrophy. It is the leading genetic cause of infant death. Revolutionary gene therapies and SMN-enhancing drugs have transformed treatment.

There are currently 7 spinal muscular atrophy clinical trials recruiting participants in Indianapolis, INDIANA. These studies are seeking a combined 1,192 participants. Research is being sponsored by Amgen, Greg Durm, MD, Boehringer Ingelheim and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Spinal Muscular Atrophy Clinical Trials in Indianapolis — FAQ

Are there spinal muscular atrophy clinical trials in Indianapolis?

Yes, there are 7 spinal muscular atrophy clinical trials currently recruiting in Indianapolis, INDIANA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Indianapolis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Indianapolis research site will contact you about next steps.

Are clinical trials in Indianapolis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Indianapolis studies also compensate for your time and travel.

What spinal muscular atrophy treatments are being tested?

The 7 active trials in Indianapolis are testing new therapies including novel drugs, biologics, and treatment approaches for spinal muscular atrophy.

Data updated March 2, 2026 from ClinicalTrials.gov