17 Ankylosing Spondylitis Clinical Trials in Iowa City, IA (2026)

Q: How do I join a clinical trial in Iowa City?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Iowa City research site will contact you.

Recruiting Ankylosing Spondylitis Studies in Iowa City

NCT00900198Recruiting

Collection of Tissue Samples for Cancer Research

Background: -Patients who are being evaluated and/or treated at the NIH Clinical Center and adult patients at participating sites will be entered onto this tissue procurement protocol for collection ...

Iowa City, IA5,000 participantsNational Cancer Institute (NCI)

View Study Details

NCT01193075Recruiting

Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

This is an observational longitudinal study to determine the natural history and genotype-phenotype correlations of disease causing mutations in Charcot Marie Tooth disease (CMT) type 1B (CMT1B), 2A (...

Iowa City, IA5,000 participantsMichael Shy

View Study Details

NCT04543461Recruiting

American Lung Association (ALA) Lung Health Cohort

The ALA-LHC is a longitudinal, multi-center cohort study that will enroll approximately 4,000 young adults between the ages of 25-35 who do not have severe lung disease. The overarching objective of t...

Iowa City, IA4,000 participantsJohns Hopkins University

View Study Details

NCT04124120Recruiting

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

The central hypothesis of ROMA:Women is that the use of multiple arterial grafting (MAG) will improve clinical outcomes and quality of life (QOL) compared to single arterial grafting (SAG). The speci...

Iowa City, IANA2,300 participantsWeill Medical College of Cornell University

View Study Details

NCT06667414Recruiting

Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers

For participation in this epidemiological study, a single-day visit at the study site is required. Participants will be recruited from Huntington Disease clinics, and they will be asked to answer ques...

Iowa City, IA600 participantsHoffmann-La Roche

View Study Details

NCT07218926Recruiting

A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

The purpose of this study is to find out if a new drug, called IDRX-42 (also known as GSK6042981), is effective in treating adults with a type of cancer called Gastrointestinal Stromal Tumors (GIST) w...

Iowa City, IAPHASE3450 participantsGlaxoSmithKline

View Study Details

NCT06026410Recruiting

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

This first-in-human (FIH) dose-escalation and dose-validation/expansion study will assess KO-2806, a farnesyltransferase inhibitor (FTI), as a monotherapy and in combination, in adult patients with ad...

Iowa City, IAPHASE1300 participantsKura Oncology, Inc.

View Study Details

NCT07206225Recruiting

A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

The purpose of this study is to learn how a new medicine called PF-08052667 works when used by itself or together with another medicine called Bacillus Calmette Guerin (BCG), and/or a medicine called ...

Iowa City, IAPHASE1294 participantsPfizer

View Study Details

NCT07630974Recruiting

A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)

Researchers are looking for new ways to treat children with relapsed or refractory solid tumors: * Relapsed means the cancer came back after treatment * Refractory means the cancer did not respond (g...

Iowa City, IAPHASE1134 participantsMerck Sharp & Dohme LLC

View Study Details

NCT06519955Recruiting

Can PLIA Reduce Early Post-operative Pain After PAO Surgery?

The goal of this clinical trial is to compare different peri-incisional local infiltrative anesthesia (PLIA) methods in patients ages 13 to 50 undergoing a periacetabular osteotomy (PAO). The main que...

Iowa City, IAPHASE2120 participantsMichael C Willey

View Study Details

NCT06756932Recruiting

BGB-21447 (Bcl-2 Inhibitor) Combinations for Adults With Hormone-Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Metastatic Breast Cancer

This is a dose escalation and dose expansion study to assess the safety and tolerability of BGB-21447 (a B-cell leukemia/lymphoma 2 inhibitor, Bcl-2i) in combination with fulvestrant, with or without ...

Iowa City, IAPHASE1120 participantsBeOne Medicines

View Study Details

NCT06663358Recruiting

A Multi-Country Observational Study of Safety and Effectiveness of Elfabrio® in Fabry Patients

A multi-centre, multi-country, observational, non-interventional, retrospective and prospective (hybrid) study among Fabry disease participants treated with pegunigalsidase alfa (Elfabrio®) in routine...

Iowa City, IA100 participantsChiesi Farmaceutici S.p.A.

View Study Details

NCT06958536Recruiting

A Study to Investigate Efficacy and Safety of SAR442970 in Patients With Crohn's Disease

This is a phase 2b, randomized, double-blind, 3-arm study for the treatment of Crohn's disease. The primary objective of this study is to assess the efficacy of different doses of SAR442970 compared w...

Iowa City, IAPHASE299 participantsSanofi

View Study Details

NCT07109219Recruiting

Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

The study is intended to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of AZD4512 in patients with relapsed/refractory B-Cell acute lymphoblastic leukemia (r/r B-AL...

Iowa City, IAPHASE183 participantsAstraZeneca

View Study Details

NCT03096418Recruiting

Neoadjuvant Weekly Paclitaxel and Biomarkers of Therapy Response

The hypothesis of this study is that paclitaxel levels increase chromosomal instability (CIN) in tumors and this is lethal to tumors that have pre-existing CIN. Treatment will be administered on an ou...

Iowa City, IAPHASE450 participantsUniversity of Wisconsin, Madison

View Study Details

NCT06207318Recruiting

Acceptance and Commitment Therapy for Patients Undergoing Coronary Artery Bypass Graft Surgery

Heart disease is the leading cause of death globally, accounting for 16% of the world's total deaths. The number of cases is expected to increase as our population ages. Heart disease also results in ...

Iowa City, IANA30 participantsUniversity of Iowa

View Study Details

NCT00567073Recruiting

Pompe Pregnancy Sub-Registry

This Sub-registry is a multicenter, international, longitudinal, observational, and voluntary program designed to track pregnancy outcomes for any pregnant woman enrolled in the Pompe Registry, regard...

Iowa City, IA20 participantsGenzyme, a Sanofi Company

View Study Details

About Ankylosing Spondylitis Clinical Trials in Iowa City

Ankylosing spondylitis is a chronic inflammatory disease primarily affecting the spine and sacroiliac joints, causing pain, stiffness, and potentially spinal fusion. It typically begins in early adulthood. Treatment includes NSAIDs, biologics (TNF and IL-17 inhibitors), and physical therapy.

There are currently 17 ankylosing spondylitis clinical trials recruiting participants in Iowa City, IA. These studies are seeking a combined 18,700 participants. Research is being sponsored by National Cancer Institute (NCI), Michael Shy, Johns Hopkins University and 14 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ankylosing Spondylitis Clinical Trials in Iowa City — FAQ

Are there ankylosing spondylitis clinical trials in Iowa City?

Yes, there are 17 ankylosing spondylitis clinical trials currently recruiting in Iowa City, IA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Iowa City?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Iowa City research site will contact you about next steps.

Are clinical trials in Iowa City free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Iowa City studies also compensate for your time and travel.

What ankylosing spondylitis treatments are being tested?

The 17 active trials in Iowa City are testing new therapies including novel drugs, biologics, and treatment approaches for ankylosing spondylitis.

Data updated July 19, 2026 from ClinicalTrials.gov