Recruiting Depression Studies in Irvine
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
X-NOVA2 is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of azetukalner as a monotherapy in adult participants ...
Study to Assess the Effects of Oral NMRA-335140 in Participants With Major Depressive Disorder
This randomized, double-blind, placebo-controlled, multicenter study will evaluate the effects of NMRA-335140 (formerly BTRX-335140) on symptoms of depression in participants with Major Depressive Dis...
GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder
The goal of this clinical trial is to learn if GATE-251 works to treat depression in adults. It will also learn about the safety of GATE-251. The main questions it aims to answer are: Does GATE-251 r...
About Depression Clinical Trials in Irvine
Depression (major depressive disorder) is a common and serious mood disorder that negatively affects how you feel, think, and handle daily activities. It affects over 280 million people globally. Treatment includes psychotherapy, antidepressant medications, and brain stimulation therapies.
There are currently 3 depression clinical trials recruiting participants in Irvine, CALIFORNIA. These studies are seeking a combined 946 participants. Research is being sponsored by Xenon Pharmaceuticals Inc., Neumora Therapeutics, Inc., Syndeio Biosciences, Inc. Clinical trial participation is free and participants receive study-related medical care at no cost.
Depression Clinical Trials in Irvine — FAQ
Are there depression clinical trials in Irvine?
Yes, there are 3 depression clinical trials currently recruiting in Irvine, CALIFORNIA. Browse the studies on this page to find one that fits.
How do I join a clinical trial in Irvine?
Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Irvine research site will contact you about next steps.
Are clinical trials in Irvine free?
Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Irvine studies also compensate for your time and travel.
What depression treatments are being tested?
The 3 active trials in Irvine are testing new therapies including novel drugs, biologics, and treatment approaches for depression.
Data updated March 2, 2026 from ClinicalTrials.gov