12 ALS Clinical Trials in Jacksonville, FL (2026)

Q: How do I join a clinical trial in Jacksonville?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Jacksonville research site will contact you.

Recruiting ALS Studies in Jacksonville

NCT05474235Recruiting

Studies in Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Motor Neuron Disorders

The purpose of this study is to collect, from patients with sporadic and familial ALS and their family members, clinical data and blood samples for extraction of DNA, RNA, preparation of lymphocytes, ...

Jacksonville, FL3,000 participantsMayo Clinic

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NCT05137665Recruiting

Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures

The goal of the study is to generate a biorepository of longitudinal biofluids-blood (plasma and serum), cerebral spinal fluid (CSF) and urine linked to genetics and longitudinal clinical information ...

Jacksonville, FL1,000 participantsTarget ALS Foundation, Inc.

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NCT06581861Recruiting

PREVENT ALL ALS Study

The ALL ALS Clinical Research Consortium is establishing research to collect a wide range of samples, clinical information and measurements from Amyotrophic Lateral Sclerosis (ALS) symptomatic, ALS ge...

Jacksonville, FL600 participantsSt. Joseph's Hospital and Medical Center, Phoenix

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NCT07322003Recruiting

Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS

The goal of this clinical trial is to learn if the drug pridopidine works to treat amyotrophic lateral sclerosis in adults. It will also help to learn about the safety of pridopidine. The main questio...

Jacksonville, FLPHASE3500 participantsPrilenia

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NCT07498426Recruiting

A Study to Evaluate the Efficacy of NIO752 in Participants With Progressive Supranuclear Palsy

This Phase III study is intended to evaluate the efficacy and safety of NIO752 in participants with Progressive Supranuclear Palsy (PSP). Eligible participants will be randomized to receive either NIO...

Jacksonville, FLPHASE3300 participantsNovartis Pharmaceuticals

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NCT03833622Recruiting

Shared Decision Making to Improve Goals of Care in the ED

This project will develop and refine a shared decision making (SDM) intervention (decision aid tool) to improve and normalize high quality end of life discussions in the Emergency Department (ED) sett...

Jacksonville, FLNA230 participantsMayo Clinic

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NCT07142291Recruiting

PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS

The purpose of this study is to test the effects of PHENOGENE-1A, which is the treatment under investigation in this study. This research will investigate if PHENOGENE-1A can help people with ALS by m...

Jacksonville, FLPHASE2105 participantsPhenoNet, Inc.

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NCT05116943Recruiting

Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders

The purpose of this study is to collect CSF and blood samples that can be used in future research studies to identify potential biomarkers in blood and cerebrospinal fluid (CSF) collected in Amyotroph...

Jacksonville, FL100 participantsMayo Clinic

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NCT06527222Recruiting

A Study of Ranolazine in ALS

The purpose of this study is to evaluate safety, effect on cramps, function and quality of life of ranolazine versus placebo for the treatment of ALS....

Jacksonville, FLPHASE272 participantsSwathy Chandrashekhar, MBBS

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NCT05395624Recruiting

Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers

This is a Phase 1/2 study to evaluate the safety and tolerability of 18F-OP-801 in subjects with ALS, AD, MS, PD and age-matched HVs. 18F-OP-801 is intended as a biomarker for PET imaging of activated...

Jacksonville, FLPHASE165 participantsAshvattha Therapeutics, Inc.

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NCT06665165Recruiting

AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis

This study is a placebo-controlled Phase I study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of the antisense oligonucleotide (ASO) AMX0114 in adult participants with ...

Jacksonville, FLPHASE148 participantsAmylyx Pharmaceuticals Inc.

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NCT07287397Recruiting

Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS

PIONEER-ALS is a Phase 1/2, multicenter, open-label, ascending dose, uncontrolled, first-in-human study that will evaluate the safety, tolerability and effects on clinical and biomarker endpoints of i...

Jacksonville, FLPHASE112 participantsVector Y Therapeutics

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About ALS Clinical Trials in Jacksonville

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects motor neurons controlling voluntary muscle movement. Also known as Lou Gehrig's disease, it leads to increasing paralysis. Research is actively pursuing disease-modifying treatments and gene therapies.

There are currently 12 als clinical trials recruiting participants in Jacksonville, FL. These studies are seeking a combined 6,032 participants. Research is being sponsored by Mayo Clinic, Target ALS Foundation, Inc., St. Joseph's Hospital and Medical Center, Phoenix and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

ALS Clinical Trials in Jacksonville — FAQ

Are there als clinical trials in Jacksonville?

Yes, there are 12 als clinical trials currently recruiting in Jacksonville, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Jacksonville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Jacksonville research site will contact you about next steps.

Are clinical trials in Jacksonville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Jacksonville studies also compensate for your time and travel.

What als treatments are being tested?

The 12 active trials in Jacksonville are testing new therapies including novel drugs, biologics, and treatment approaches for als.

Data updated September 2, 2026 from ClinicalTrials.gov