5 Head and Neck Cancer Clinical Trials in Jacksonville, FL (2026)

Q: How do I join a clinical trial in Jacksonville?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Jacksonville research site will contact you.

Recruiting Head and Neck Cancer Studies in Jacksonville

NCT06788990Recruiting

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

Ficerafusp alfa is directed against two targets, Epidermal Growth Factor Receptor (EGFR) and Transforming Growth Factor beta (TGF-β). This study intends to evaluate the safety and efficacy of ficeraf...

Jacksonville, FLPHASE2650 participantsBicara Therapeutics

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NCT05451004Recruiting

SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer

This study is being done to answer the following question: Is the chance of cancer spreading or returning the same if radiotherapy to the neck is guided, by using a special imaging study called lymph...

Jacksonville, FLPHASE3510 participantsCanadian Cancer Trials Group

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NCT04892173Recruiting

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

This is a global, open-label, randomized, 2-arm, Investigator's choice Phase 3 (Pivotal Stage) study to investigate the efficacy and safety of JNJ-90301900 (NBTXR3) / radiation therapy (RT)±cetuximab ...

Jacksonville, FLPHASE3500 participantsJohnson & Johnson Enterprise Innovation Inc.

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NCT05541016Recruiting

De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA

This phase II trial examines the use of blood-based biomarkers is to help inform decision making for treatment and radiation therapy for patients with human papillomavirus (HPV) positive oropharyngeal...

Jacksonville, FLPHASE2455 participantsMayo Clinic

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NCT05268614Recruiting

Risk Adapted De-Intensification of Radio-Chemotherapy for Oropharyngeal Squamous Cell Carcinoma

This study builds on the results of several prior studies that we have been involved with to test the hypothesis that Risk-Adapted De-Intensification of Radiation Therapy and chemotherapy based on HPV...

Jacksonville, FLPHASE2250 participantsUniversity of Florida

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About Head and Neck Cancer Clinical Trials in Jacksonville

Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.

There are currently 5 head and neck cancer clinical trials recruiting participants in Jacksonville, FL. These studies are seeking a combined 2,365 participants. Research is being sponsored by Bicara Therapeutics, Canadian Cancer Trials Group, Johnson & Johnson Enterprise Innovation Inc. and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Head and Neck Cancer Clinical Trials in Jacksonville — FAQ

Are there head and neck cancer clinical trials in Jacksonville?

Yes, there are 5 head and neck cancer clinical trials currently recruiting in Jacksonville, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Jacksonville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Jacksonville research site will contact you about next steps.

Are clinical trials in Jacksonville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Jacksonville studies also compensate for your time and travel.

What head and neck cancer treatments are being tested?

The 5 active trials in Jacksonville are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.

Data updated October 15, 2026 from ClinicalTrials.gov