Jacksonville, FL7 Active Studies

Head and Neck Cancer Clinical Trials in Jacksonville, FL

Find 7 actively recruiting head and neck cancer clinical trials in Jacksonville, FL. Connect with local research sites and explore new treatment options.

7
Active Trials
6
Sponsors
1,811
Enrolling

Recruiting Head and Neck Cancer Studies in Jacksonville

RecruitingJacksonville, FLNCT05451004

SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer

This study is being done to answer the following question: Is the chance of cancer spreading or returning the same if radiotherapy to the neck is guided, by using a special imaging study called lymph...

510 participants
Canadian Cancer Trials Group
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RecruitingJacksonville, FLNCT06790966

Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

This is a global, multi-center, Phase 3 study that is randomized 2:1, controlled, and open label to evaluate PDS0101 (Versamune + HPVMix) in combination with pembrolizumab vs. pembrolizumab monotherap...

351 participants
PDS Biotechnology Corp.
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RecruitingJacksonville, FLNCT05541016

De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA

This phase II trial examines the use of blood-based biomarkers is to help inform decision making for treatment and radiation therapy for patients with human papillomavirus (HPV) positive oropharyngeal...

320 participants
Mayo Clinic
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RecruitingJacksonville, FLNCT05268614

Risk Adapted De-Intensification of Radio-Chemotherapy for Oropharyngeal Squamous Cell Carcinoma

This study builds on the results of several prior studies that we have been involved with to test the hypothesis that Risk-Adapted De-Intensification of Radiation Therapy and chemotherapy based on HPV...

250 participants
University of Florida
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RecruitingJacksonville, FLNCT05075980

Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT Study

This clinical trial studies how well intensity modulated proton therapy (IMPT) or intensity modulated X-ray (radiation) therapy (IMRT) works after surgery in treating patients with head and neck cance...

174 participants
Mayo Clinic
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RecruitingJacksonville, FLNCT04870762

Customized 3D Printed Oral Stents During Head and Neck Radiotherapy

This clinical trial studies the effect of customized 3 dimensional (3D) printed oral tents on patients with head and neck cancer who are receiving radiotherapy. Oral stents are made from the impressio...

119 participants
M.D. Anderson Cancer Center
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RecruitingJacksonville, FLNCT04291105

Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients

This is a Phase 2 study designed to determine the preliminary anti-tumor activity and confirm the safety of VV1 in combination with cemiplimab. The study will enroll patients with three distinct separ...

87 participants
Vyriad, Inc.
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About Head and Neck Cancer Clinical Trials in Jacksonville

Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.

There are currently 7 head and neck cancer clinical trials recruiting participants in Jacksonville, FL. These studies are seeking a combined 1,811 participants. Research is being sponsored by Canadian Cancer Trials Group, PDS Biotechnology Corp., Mayo Clinic and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Head and Neck Cancer Clinical Trials in Jacksonville — FAQ

Are there head and neck cancer clinical trials in Jacksonville?

Yes, there are 7 head and neck cancer clinical trials currently recruiting in Jacksonville, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Jacksonville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Jacksonville research site will contact you about next steps.

Are clinical trials in Jacksonville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Jacksonville studies also compensate for your time and travel.

What head and neck cancer treatments are being tested?

The 7 active trials in Jacksonville are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.

Data updated March 2, 2026 from ClinicalTrials.gov