33 Osteogenesis Imperfecta Clinical Trials in Jacksonville, FL (2026)

Q: How do I join a clinical trial in Jacksonville?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Jacksonville research site will contact you.

Recruiting Osteogenesis Imperfecta Studies in Jacksonville

NCT05112614Recruiting

Role of Gut Microbiome in Cancer Therapy

This study examines how gut microbiome can affect cancer therapy in cancer patients undergoing cancer therapy or stem cell transplant. The human microbiome affects the way some cancer drugs are metabo...

Jacksonville, FL3,000 participantsMayo Clinic

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NCT03013998Recruiting

Study of Biomarker-Based Treatment of Acute Myeloid Leukemia

This screening and multi-sub-study Phase 1b/2 trial will establish a method for genomic screening followed by assigning and accruing simultaneously to a multi-study "Master Protocol (BAML-16-001-M1)."...

Jacksonville, FL3,000 participantsBeat AML, LLC

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NCT07412002Recruiting

Quality of End-of-Life Care for Children With Cancer

This study examines the role of access to care, patient/family interactions with the healthcare system, and stress in explaining variations in quality of end of life care. The data collected from this...

Jacksonville, FL2,425 participantsChildren's Oncology Group

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NCT02958462Recruiting

Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

This clinical trial tests next generation sequencing (NGS) for the detection of precursor features of pre-myeloid cancers and bone marrow failure syndromes. NGS is a procedure that looks at relevant c...

Jacksonville, FL2,000 participantsMayo Clinic

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NCT07126496Recruiting

A Virtual Community Health Educator for Increasing Clinical Trial Referrals Among Cancer Patients and Their Caregivers

This clinical trial studies how well a virtual community health educator (vCHE) works in increasing clinical trial referrals for patients with cancer and their caregivers. Low enrollment of underrepre...

Jacksonville, FL2,000 participantsMayo Clinic

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NCT04561518Recruiting

ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

The purpose of this study is to: * Describe epidemiological and clinical characteristics, natural history and real-world clinical management of ATTR amyloidosis patients * Characterize the safety and...

Jacksonville, FL1,500 participantsAlnylam Pharmaceuticals

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NCT06353191Recruiting

Biomarkers to Predict Cancer Therapy-related Cardiotoxicity

This study evaluates why some cancer patients but not others experience changes in heart function following treatment with chemotherapy....

Jacksonville, FL1,000 participantsMayo Clinic

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NCT06198010Recruiting

A Collaborative Intervention for Improving Cancer Pain Management in Cancer Survivors

This clinical trial tests a collaborative pain management intervention (ASCENT) for improving cancer pain in cancer survivors. Cancer pain is prevalent, under-treated, and remains a major cause of suf...

Jacksonville, FL660 participantsMayo Clinic

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NCT06207188Recruiting

Identification and Differentiation of Thyroid Nodules by Acoustic Imaging and Viscoelastic Parameters

This study is being done to identify and differentiate thyroid nodules by acoustic imaging and viscoelastic parameters....

Jacksonville, FL650 participantsMayo Clinic

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NCT06563895Recruiting

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

Transthyretin amyloidosis (ATTR) is a disease where the normally occurring transthyretin (TTR) protein falls apart and forms amyloid, a sticky plaque- like substance that accumulates in different orga...

Jacksonville, FL587 participantsEidos Therapeutics, a BridgeBio company

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NCT07022678Recruiting

Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia

This phase III trial compares the effect of xylitol dental wipes to dental wipes without xylitol for the reduction of bloodstream infection in children with acute myeloid leukemia (AML). Xylitol is a ...

Jacksonville, FL556 participantsChildren's Oncology Group

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NCT05208047Recruiting

(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors

This is a Phase 3, open-label, international, multicenter study of CGT9486 in combination with sunitinib. This is a multi-part study that will enroll approximately 482 patients. Part 1 consists of two...

Jacksonville, FL482 participantsCogent Biosciences, Inc.

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NCT07218926Recruiting

A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

The purpose of this study is to find out if a new drug, called IDRX-42 (also known as GSK6042981), is effective in treating adults with a type of cancer called Gastrointestinal Stromal Tumors (GIST) w...

Jacksonville, FL450 participantsGlaxoSmithKline

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NCT05735184Recruiting

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

Ziftomenib is an investigational drug in development for the treatment of patients with acute myeloid leukemia (AML) with certain genetic alterations. This protocol has 3 separate arms that will inve...

Jacksonville, FL420 participantsKura Oncology, Inc.

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NCT05619588Recruiting

Exactech Vantage Total Ankle System Post Market Clinical Follow-Up - US Only

The objectives of this study are to evaluate the performance and safety of the Vantage Total Ankle System. This study will follow subjects for a period of up to 10 years post-surgery....

Jacksonville, FL370 participantsExactech

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NCT07608354Recruiting

A Study to Evaluate the Efficacy and Safety of Concomitant Use of Eplontersen and ALXN2220 Compared With Eplontersen and Placebo for Adults Participants With ATTR-CM

The purpose of this randomised, double-blind, placebo-controlled, multicenter study is to evaluate the efficacy and safety of concomitant use of eplontersen and ALXN2220 compared with eplontersen and ...

Jacksonville, FL326 participantsAstraZeneca

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NCT07276581Recruiting

A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis

Phase II study in participants with moderately-to-severely active rheumatoid Arthritis (RA) to evaluate efficacy and safety of AZD1163....

Jacksonville, FL320 participantsAstraZeneca

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NCT06651177Recruiting

Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder

The primary objective of this research study is to evaluate the effect of tirzepatide, relative to placebo, as an adjunct to BUP on retention, substance use, and sleep outcomes in individuals with OUD...

Jacksonville, FL310 participantsT. John Winhusen, PhD

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NCT02074839Recruiting

Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

The purpose of this Phase I, multicenter study is to evaluate the safety, pharmacokinetics, pharmacodynamics and clinical activity of AG-120 in advanced hematologic malignancies that harbor an IDH1 mu...

Jacksonville, FL291 participantsInstitut de Recherches Internationales Servier

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NCT07285213Recruiting

Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal Antibody

The purpose of this study is to evaluate the efficacy and safety of AZD5148 for prevention of recurrence of Clostridioides difficile infection in Individuals 18 years of age and above....

Jacksonville, FL230 participantsAstraZeneca

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NCT05732103Recruiting

A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

The goal of this phase 1/2 multicenter, open-label, single-arm dose escalation and expansion study is to assess the safety, tolerability, pharmacokinetic and pharmacodynamic profile of CTX-712 in pati...

Jacksonville, FL225 participantsChordia Therapeutics, Inc.

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NCT06393712Recruiting

A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy

The purpose of the study is to evaluate the effect of ALN-APP on measures of CAA disease progression and to characterize the safety, tolerability, and pharmacodynamics (PD) of ALN-APP in adult patient...

Jacksonville, FL200 participantsAlnylam Pharmaceuticals

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NCT06630234Recruiting

A Master Protocol to Evaluate DCC-3009 in Gastrointestinal Stromal Tumor (GIST)

The purpose of this Phase 1/2 master protocol study is to evaluate if DCC-3009 is safe, tolerable and works effectively in the treatment of GIST. The study will use a modular approach with each module...

Jacksonville, FL120 participantsDeciphera Pharmaceuticals, LLC

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NCT05711667Recruiting

A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

This phase III single arm trial determines whether taking prophylactic letermovir will reduce the likelihood of infection with cytomegalovirus (CMV) in children and adolescents after stem cell transpl...

Jacksonville, FL105 participantsChildren's Oncology Group

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NCT05890729Recruiting

A Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis

A phase 1b/2 study of XTMAB-16 in patients with pulmonary sarcoidosis...

Jacksonville, FL94 participantsXentria, Inc.

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NCT06401044Recruiting

A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease

The primary objective of Part A of this study is to investigate the safety and tolerability of AMG 732 after single subcutaneous (SC) doses. The primary objective of Part B of this study is to investi...

Jacksonville, FL88 participantsAmgen

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NCT06279572Recruiting

Immune Profile of Acute Myeloid Leukemia Patients Receiving Azacitidine Plus Venetoclax Induction Chemotherapy

This study investigates the immune profile of patients receiving treatment with venetoclax plus azacitidine for acute myeloid leukemia (AML). Studying the information gathered from the immune profile ...

Jacksonville, FL80 participantsMayo Clinic

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NCT07406633Recruiting

KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (SynerGIST-1st Line)

This study will test an experimental drug called KQB198 in combination with imatinib. The goal is to determine if this combination is safe and tolerable and assess how effective the combination is at ...

Jacksonville, FL46 participantsKumquat Biosciences Inc.

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NCT06640010Recruiting

Using Induced-Pluripotent Stem Cells to Model Cancer Therapy-Related Adverse Events

This study is being done to find out if patient blood samples can be used to perform individualized modeling of cancer therapy-related side effects....

Jacksonville, FL30 participantsMayo Clinic

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NCT07285044Recruiting

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

This phase II trial studies whether providing cancer treatment in the home is preferred over the traditional clinic setting and if it improves treatment satisfaction in cancer patients living in the F...

Jacksonville, FL27 participantsMayo Clinic

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NCT04167696Recruiting

Study in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Patients to Determine the Recommended Dose of CYAD-02

An open-label, phase I, multi-center study to determine in relapsed/refractory (r/r) acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) patients the recommended dose of CYAD-02 after a non...

Jacksonville, FL27 participantsCelyad Oncology SA

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NCT07545837Recruiting

Health and Wellness Coaching to Improve Adherence to Healthy Habits and Treatment Plans in Papillary and Follicular Thyroid Cancer Survivors

This clinical trial evaluates the impact of a patient-centered health and wellness coaching (HWC) intervention on adherence to treatment plans and healthy lifestyle practices in patients with papillar...

Jacksonville, FL20 participantsMayo Clinic

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NCT06262126Recruiting

Virtual Reality for Non-cardiac Chest Pain

The purpose of this study is to determine if virtual reality (VR) will improve symptoms in non-cardiac chest pain (NCCP)....

Jacksonville, FL10 participantsMayo Clinic

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About Osteogenesis Imperfecta Clinical Trials in Jacksonville

Osteogenesis imperfecta is a group of genetic disorders mainly affecting the bones, causing them to break easily, often from little or no apparent cause. It is caused by defects in collagen production. Treatment includes bisphosphonates, physical therapy, and surgical rodding.

There are currently 33 osteogenesis imperfecta clinical trials recruiting participants in Jacksonville, FL. These studies are seeking a combined 21,649 participants. Research is being sponsored by Mayo Clinic, Beat AML, LLC, Children's Oncology Group and 15 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Osteogenesis Imperfecta Clinical Trials in Jacksonville — FAQ

Are there osteogenesis imperfecta clinical trials in Jacksonville?

Yes, there are 33 osteogenesis imperfecta clinical trials currently recruiting in Jacksonville, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Jacksonville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Jacksonville research site will contact you about next steps.

Are clinical trials in Jacksonville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Jacksonville studies also compensate for your time and travel.

What osteogenesis imperfecta treatments are being tested?

The 33 active trials in Jacksonville are testing new therapies including novel drugs, biologics, and treatment approaches for osteogenesis imperfecta.

Data updated July 13, 2026 from ClinicalTrials.gov