Jacksonville, FLORIDA11 Active Studies

Advanced Solid Tumors Clinical Trials in Jacksonville, FLORIDA

Find 11 actively recruiting advanced solid tumors clinical trials in Jacksonville, FLORIDA. Connect with local research sites and explore new treatment options.

11
Active Trials
10
Sponsors
2,825
Enrolling

Recruiting Advanced Solid Tumors Studies in Jacksonville

RecruitingJacksonville, FLORIDANCT04657068

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

This clinical trial is evaluating a drug called ART0380 in participants with advanced or metastatic solid tumors. The main goals of this study are to: * Find the recommended dose of ART0380 that can ...

597 participants
Artios Pharma Ltd
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RecruitingJacksonville, FLORIDANCT05824975

A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and therapeutic activity of GI-102 as a single agent and in combination with conventional anti-cancer drugs, pembro...

358 participants
GI Innovation, Inc.
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RecruitingJacksonville, FLORIDANCT05315700

Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

The purpose of this study is to establish the recommended Phase 2 dose (RP2D) and/or maximum tolerated dose (MTD), safety, pharmacokinetics (PK), pharmacodynamics (PD), and antitumor activity of ORIC-...

350 participants
ORIC Pharmaceuticals
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RecruitingJacksonville, FLORIDANCT05597839

Study of DF9001 in Patients With Advanced Solid Tumors

DF9001-001 is a study of a new molecule that targets natural killer (NK) cells and T-cell activation signals to specific receptors on cancer cells. The study will occur in two phases. The first phase ...

242 participants
Dragonfly Therapeutics
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RecruitingJacksonville, FLORIDANCT06682793

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

The goal of this study is to test A2B395, an allogeneic logic-gated Tmod™ CAR T-cell product in subjects with solid tumors including colorectal cancer (CRC), non-small cell lung cancer (NSCLC), head a...

240 participants
A2 Biotherapeutics Inc.
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RecruitingJacksonville, FLORIDANCT06051695

A Study to Evaluate the Safety and Efficacy of A2B694, a Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

The goal of this study is to test A2B694, an autologous logic-gated Tmod™ CAR T-cell product in subjects with solid tumors including colorectal cancer (CRC), pancreatic cancer (PANC), non-small cell l...

230 participants
A2 Biotherapeutics Inc.
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RecruitingJacksonville, FLORIDANCT04939610

A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

Fibroblast activation protein (FAP) is a cell surface protein that is highly expressed on the surface of cancer-associated fibroblasts (CAFs) present in the tumor microenvironment of most epithelial c...

222 participants
Novartis Pharmaceuticals
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RecruitingJacksonville, FLORIDANCT05969860

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

This clinical trial studies the effect of cancer directed therapy given at-home versus in the clinic for patients with cancer that may have spread from where it first started to nearby tissue, lymph n...

200 participants
Mayo Clinic
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RecruitingJacksonville, FLORIDANCT04896697

Vilastobart (XTX101) Monotherapy and Vilastobart and Atezolizumab Combination Therapy in Advanced Solid Tumors

This is a first-in-human, Phase 1/2, multicenter, open-label study designed to evaluate the safety and tolerability of vilastobart (XTX101) as monotherapy and vilastobart (XTX101) and atezolizumab com...

136 participants
Xilio Development, Inc.
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RecruitingJacksonville, FLORIDANCT05394103

Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors

Multicenter, open-label, dose-escalation, safety, tolerability, PK and pharmacodynamic study with a dose expansion at the RP2D to evaluate safety and potential antitumor activity of Q901 as a monother...

130 participants
Qurient Co., Ltd.
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RecruitingJacksonville, FLORIDANCT06395519

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

This is a two-part, open-label, multicenter, dose escalation and dose expansion study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PDx), and anti- tumor acti...

120 participants
858 Therapeutics, Inc.
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About Advanced Solid Tumors Clinical Trials in Jacksonville

Advanced solid tumors refer to cancers that have grown beyond the original site or spread to distant organs. Many clinical trials enroll patients with various types of advanced solid tumors to test novel therapies. These trials often investigate immunotherapy, targeted therapy, and combination approaches.

There are currently 11 advanced solid tumors clinical trials recruiting participants in Jacksonville, FLORIDA. These studies are seeking a combined 2,825 participants. Research is being sponsored by Artios Pharma Ltd, GI Innovation, Inc., ORIC Pharmaceuticals and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Advanced Solid Tumors Clinical Trials in Jacksonville — FAQ

Are there advanced solid tumors clinical trials in Jacksonville?

Yes, there are 11 advanced solid tumors clinical trials currently recruiting in Jacksonville, FLORIDA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Jacksonville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Jacksonville research site will contact you about next steps.

Are clinical trials in Jacksonville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Jacksonville studies also compensate for your time and travel.

What advanced solid tumors treatments are being tested?

The 11 active trials in Jacksonville are testing new therapies including novel drugs, biologics, and treatment approaches for advanced solid tumors.

Data updated March 2, 2026 from ClinicalTrials.gov