La Jolla, CA5 Active Studies

Depression Clinical Trials in La Jolla, CA

Find 5 actively recruiting depression clinical trials in La Jolla, CA. Connect with local research sites and explore new treatment options.

5
Active Trials
5
Sponsors
1,310
Enrolling

Recruiting Depression Studies in La Jolla

RecruitingLa Jolla, CANCT05711940

Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD

Efficacy, Safety, and Tolerability of two administrations of COMP360 in participants with treatment-resistant depression (TRD)...

568 participants
COMPASS Pathways
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RecruitingLa Jolla, CANCT06308653

Psilocybin for Major Depressive Disorder (MDD)

Approximately 240 eligible adult participants (≥18 years old) who meet Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR) criteria for Major Depressive Disorder (MDD) will be enrolled. P...

240 participants
Usona Institute
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RecruitingLa Jolla, CANCT06564818

"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"

The purpose of this study is to examine the efficacy, safety, and tolerability of CYB003 compared to matching placebo as adjunctive treatment in participants with MDD....

220 participants
Cybin IRL Limited
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RecruitingLa Jolla, CANCT06524830

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

This Phase 2 study (protocol number VLS-01-203) will determine the efficacy, safety, and tolerability of short-term treatment with a VLS-01 transmucosal buccal film (VLS-01-BU) in patients with treatm...

142 participants
atai Therapeutics, Inc.
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RecruitingLa Jolla, CANCT06941844

A Phase 3 Trial of MM120 for Major Depressive Disorder (Emerge)

A Phase 3 Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating MM120 Compared to Placebo in Major Depressive Disorder - Emerge...

140 participants
Mind Medicine, Inc.
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About Depression Clinical Trials in La Jolla

Depression (major depressive disorder) is a common and serious mood disorder that negatively affects how you feel, think, and handle daily activities. It affects over 280 million people globally. Treatment includes psychotherapy, antidepressant medications, and brain stimulation therapies.

There are currently 5 depression clinical trials recruiting participants in La Jolla, CA. These studies are seeking a combined 1,310 participants. Research is being sponsored by COMPASS Pathways, Usona Institute, Cybin IRL Limited and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Depression Clinical Trials in La Jolla — FAQ

Are there depression clinical trials in La Jolla?

Yes, there are 5 depression clinical trials currently recruiting in La Jolla, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in La Jolla?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the La Jolla research site will contact you about next steps.

Are clinical trials in La Jolla free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many La Jolla studies also compensate for your time and travel.

What depression treatments are being tested?

The 5 active trials in La Jolla are testing new therapies including novel drugs, biologics, and treatment approaches for depression.

Data updated March 2, 2026 from ClinicalTrials.gov