11 Rheumatoid Arthritis Clinical Trials in Lancaster, PA (2026)

Q: How do I join a clinical trial in Lancaster?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Lancaster research site will contact you.

Recruiting Rheumatoid Arthritis Studies in Lancaster

NCT07018700Recruiting

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic Migraine

In this clinical trial, participants with episodic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine d...

Lancaster, PAPHASE3990 participantsMerz Therapeutics GmbH

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NCT07196748Recruiting

A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this protocol is to evaluate the efficacy (how well it works), safety and tolerability of oral icotrokinra as therapy in adult and adolescent participants with moderately to severely ac...

Lancaster, PAPHASE3882 participantsJanssen Research & Development, LLC

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NCT07018713Recruiting

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine

In this clinical trial, participants with chronic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine da...

Lancaster, PAPHASE3780 participantsMerz Therapeutics GmbH

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NCT07012395Recruiting

A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

This is a Phase 2, multicenter, proof-of-concept platform study in adult participants with moderately to severely active ulcerative colitis (UC). The primary goal of the study is to assess the efficac...

Lancaster, PAPHASE2645 participantsSpyre Therapeutics, Inc.

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NCT06588855Recruiting

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction therapy with Afimkibart (RO7790121) compared with placebo in participants with mo...

Lancaster, PAPHASE3350 participantsHoffmann-La Roche

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NCT05488340Recruiting

A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial)

This is a Phase 2 superiority study of LBP-EC01, a recombinant bacteriophage cocktail, with an initial open-label 3-arm pharmacokinetic (PK) lead-in portion of 30 patients to evaluate the optimal dosi...

Lancaster, PAPHASE2318 participantsLocus Biosciences

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NCT07186101Recruiting

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

The main purpose of the study is to evaluate the effectiveness and safety of LY4268989 when given with mirikizumab compared to mirikizumab alone in adult participants with moderately to severely activ...

Lancaster, PAPHASE2252 participantsEli Lilly and Company

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NCT06979336Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

The purpose of this study is to evaluate the efficacy of RO7837195 compared with placebo in participants with moderately to severely active ulcerative colitis for whom prior treatment with conventiona...

Lancaster, PAPHASE2224 participantsGenentech, Inc.

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NCT06029972Recruiting

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis

The goal of this study is to learn if tilpisertib fosmecarbil (formerly known as GS-5290) is effective and safe in treating participants with moderate to severe ulcerative colitis. The study will comp...

Lancaster, PAPHASE2176 participantsGilead Sciences

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NCT06598943Recruiting

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

The main purpose of this study is to determine the safety and efficacy of eltrekibart and mirikizumab in adult participants with moderately to severely active ulcerative colitis (UC)....

Lancaster, PAPHASE2140 participantsEli Lilly and Company

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NCT06975722Recruiting

A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

This is a phase 2b, randomized, double-blind, 3-arm study for the treatment of Ulcerative Colitis. The primary objective of this study is to assess the efficacy of different doses of SAR442970 compare...

Lancaster, PAPHASE299 participantsSanofi

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About Rheumatoid Arthritis Clinical Trials in Lancaster

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting approximately 1.3 million Americans, where the immune system mistakenly attacks joint linings, causing painful swelling, bone erosion, and joint deformity. Early diagnosis and treatment are critical to prevent irreversible damage. Current standard treatments include methotrexate and other DMARDs, TNF inhibitors (etanercept, infliximab), IL-6 inhibitors (tocilizumab), T-cell costimulation modulators (abatacept), and JAK inhibitors (tofacitinib, baricitinib). Clinical trials are now exploring next-generation targeted therapies, dual-pathway inhibitors, and treatment strategies aimed at achieving sustained remission rather than just symptom control. Patients with inadequate response to conventional DMARDs or biologics are commonly eligible for enrollment.

There are currently 11 rheumatoid arthritis clinical trials recruiting participants in Lancaster, PA. These studies are seeking a combined 4,856 participants. Research is being sponsored by Merz Therapeutics GmbH, Janssen Research & Development, LLC, Spyre Therapeutics, Inc. and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Rheumatoid Arthritis Clinical Trials in Lancaster — FAQ

Are there rheumatoid arthritis clinical trials in Lancaster?

Yes, there are 11 rheumatoid arthritis clinical trials currently recruiting in Lancaster, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Lancaster?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Lancaster research site will contact you about next steps.

Are clinical trials in Lancaster free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Lancaster studies also compensate for your time and travel.

What rheumatoid arthritis treatments are being tested?

The 11 active trials in Lancaster are testing new therapies including novel drugs, biologics, and treatment approaches for rheumatoid arthritis.

Data updated July 19, 2026 from ClinicalTrials.gov