4 Substance Use Disorder Clinical Trials in Lexington, MA (2026)

Q: How do I join a clinical trial in Lexington?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Lexington research site will contact you.

Recruiting Substance Use Disorder Studies in Lexington

NCT07223398Recruiting

Shared Decision Making to Treat Or Prevent (STOP) HIV in Criminal Legal Involved Populations (R33)

This study seeks to compare the effectiveness of two Patient Navigation models of care to evaluate the proportion who initiate PrEP/ART and substance use/substance use disorder (SU/SUD) treatment. A s...

Lexington, MA400 participantsYale University

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NCT06712602Recruiting

PT150 Drug for Use in Alcohol Use Disorder

The goal of this study is to learn if PT150 can reduce the behavioral and physical effects of stress, alcohol, and alcohol use in people with alcohol use disorder....

Lexington, MA34 participantsPop Test Oncology LLC

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NCT06326684Recruiting

Suvorexant and Alcohol

This research will translate findings from preclinical research and provide the initial clinical evidence that orexin antagonism reduces motivation for alcohol, as well as other alcohol-associated mal...

Lexington, MA30 participantsWilliam Stoops

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NCT05729932Recruiting

Cannabis and Opioid Use Disorder

This study plans to enroll participants with opioid use disorder who are not currently seeking treatment to assess the effects of cannabis on opioid withdrawal and other related outcomes....

Lexington, MA15 participantsShanna Babalonis, PhD

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About Substance Use Disorder Clinical Trials in Lexington

Substance use disorder is a condition where the use of substances leads to health issues, disability, and failure to meet responsibilities. It encompasses alcohol, opioid, stimulant, and other drug addictions. Treatment includes behavioral therapy, medication-assisted treatment, and support programs.

There are currently 4 substance use disorder clinical trials recruiting participants in Lexington, MA. These studies are seeking a combined 479 participants. Research is being sponsored by Yale University, Pop Test Oncology LLC, William Stoops and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Substance Use Disorder Clinical Trials in Lexington — FAQ

Are there substance use disorder clinical trials in Lexington?

Yes, there are 4 substance use disorder clinical trials currently recruiting in Lexington, MA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Lexington?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Lexington research site will contact you about next steps.

Are clinical trials in Lexington free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Lexington studies also compensate for your time and travel.

What substance use disorder treatments are being tested?

The 4 active trials in Lexington are testing new therapies including novel drugs, biologics, and treatment approaches for substance use disorder.

Data updated July 13, 2026 from ClinicalTrials.gov