14 Pulmonary Hypertension Clinical Trials in Lexington, VA (2026)

Q: How do I join a clinical trial in Lexington?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Lexington research site will contact you.

Recruiting Pulmonary Hypertension Studies in Lexington

NCT06091865Recruiting

A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

This study is researching an experimental drug called odronextamab, referred to as study drug, when used in combination with chemotherapy. The study is focused on patients with Diffuse Large B-cell Ly...

Lexington, VA904 participantsRegeneron Pharmaceuticals

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NCT06911632Recruiting

Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

MOMENTOUS is a multi-center, randomized study to prospectively evaluate the performance of an ECG-based AI device to predict whether participants with interstitial lung disease (ILD) are at high risk ...

Lexington, VA900 participantsTempus AI

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NCT06051409Recruiting

A Study of Olverembatinib in Patients With Newly Diagnosed Ph+ ALL (POLARIS-1)

A global multicenter, open-label, randomized and registrational Phase 3 study to evaluate efficacy and safety of olverembatinib combined with chemotherapy versus investigator's choice of tyrosine kina...

Lexington, VA350 participantsAscentage Pharma Group Inc.

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NCT07226596Recruiting

Non-Abstinence Outcomes in Methamphetamine Use Disorder

Reduced drug use is a clinically meaningful target for treatment development, but few studies have evaluated the positive impacts produced by this behavioral change, preventing adoption of this endpoi...

Lexington, VA300 participantsWilliam Stoops

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NCT05139017Recruiting

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

The purpose of this Phase 2/3, randomized, multisite, open-label, dose confirmation, and expansion study is to evaluate the safety, and efficacy of zilovertamab vedotin (ZV) in combination with standa...

Lexington, VA290 participantsMerck Sharp & Dohme LLC

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NCT06581198Recruiting

A Study of Rapcabtagene Autoleucel in Systemic Lupus Erythematosus (SLE) Patients With Active, Refractory Lupus Nephritis (LN)

The purpose of this study is to evaluate the efficacy and safety of rapcabtagene autoleucel (administered once following lymphodepletion) versus Standard of Care (SOC) in patients with systemic lupus ...

Lexington, VA179 participantsNovartis Pharmaceuticals

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NCT07281079Recruiting

A Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome

This Phase 3, randomized, double-blind, parallel-group (2-arm), placebo-controlled, multicenter study will evaluate the efficacy and safety of NNZ-2591 compared to placebo in pediatric participants wi...

Lexington, VA160 participantsNeuren Pharmaceuticals Limited

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NCT05952024Recruiting

Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

The study will measure the safety, tolerability, and efficacy with acalabrutinib in combination with rituximab in treatment-naïve elderly and/or frail patients with diffuse large B-cell lymphoma (DLBC...

Lexington, VA80 participantsAstraZeneca

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NCT05778188Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia

Hypoxic-ischemic encephalopathy (HIE) affects approximately 4,000 to 12,000 persons annually in the United States. Mortality from HIE has been reported up to 60%, with at least 25% of survivors left w...

Lexington, VA70 participantsReAlta Life Sciences, Inc.

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NCT05172245Recruiting

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

This phase I/Ib trial tests the safety and best dose of ipatasertib in combination with the usual treatment approach using chemotherapy together with radiation therapy ("chemo-radiation") in patients ...

Lexington, VA46 participantsNational Cancer Institute (NCI)

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NCT06830980Recruiting

Transcranial Magnetic Stimulation for Methamphetamine Use Disorder in PLWH

The purpose of this study is to learn more about how accelerated theta burst stimulation affects methamphetamine craving and brain activity. Theta burst stimulation is a unique transcranial magnetic s...

Lexington, VA30 participantsGopalkumar Rakesh

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NCT06789159Recruiting

A Phase Ib Study of VK-2019 in Patients With Relapsed or Refractory EBV+ Diffuse Large B-cell Lymphomas (DLBCL)

This is a Phase Ib in adult patients with relapsed or refractory EBV-positive DLBCL using daily oral dosing of VK-2019 in three dose escalation cohorts: 600 mg/day, 1200 mg/day, 1800 mg/day for 28 day...

Lexington, VA30 participantsPierluigi Porcu

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NCT06631053Recruiting

FIT Exercise in 30d of ULLS-induced Muscle Disuse

This study aims to determine how flywheel-based inertial training (FIT) implemented according to principles of velocity-based training (VBT) and High-Intensity Interval Training (HIIT) affects disuse-...

Lexington, VA16 participantsLance Bollinger

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NCT06683365Recruiting

Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

This phase I double-blind study focuses on the safety and feasibility of implanting autologous peripheral nerve tissue (PNT) into the substantia nigra area of the brain in persons who have been diagno...

Lexington, VA7 participantsCraig van Horne, MD, PhD

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About Pulmonary Hypertension Clinical Trials in Lexington

Pulmonary hypertension is a type of high blood pressure that affects the arteries in the lungs and the right side of the heart. It can lead to heart failure if untreated. Treatment includes vasodilators, endothelin receptor antagonists, and PDE-5 inhibitors.

There are currently 14 pulmonary hypertension clinical trials recruiting participants in Lexington, VA. These studies are seeking a combined 3,362 participants. Research is being sponsored by Regeneron Pharmaceuticals, Tempus AI, Ascentage Pharma Group Inc. and 11 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pulmonary Hypertension Clinical Trials in Lexington — FAQ

Are there pulmonary hypertension clinical trials in Lexington?

Yes, there are 14 pulmonary hypertension clinical trials currently recruiting in Lexington, VA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Lexington?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Lexington research site will contact you about next steps.

Are clinical trials in Lexington free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Lexington studies also compensate for your time and travel.

What pulmonary hypertension treatments are being tested?

The 14 active trials in Lexington are testing new therapies including novel drugs, biologics, and treatment approaches for pulmonary hypertension.

Data updated July 13, 2026 from ClinicalTrials.gov