Little Rock, AR8 Active Studies

Bipolar Disorder Clinical Trials in Little Rock, AR

Find 8 actively recruiting bipolar disorder clinical trials in Little Rock, AR. Connect with local research sites and explore new treatment options.

8
Active Trials
5
Sponsors
2,406
Enrolling

Recruiting Bipolar Disorder Studies in Little Rock

RecruitingLittle Rock, ARNCT07172516

A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)

X-CEED is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of azetukalner in adult participants diagnosed with bipolar I or II disorder wh...

400 participants
Xenon Pharmaceuticals Inc.
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RecruitingLittle Rock, ARNCT06372964

Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients

This is a multicenter, randomized, double-blind, placebo-controlled study in pediatric patients who are experiencing major depressive episodes (MDEs) associated with a primary diagnosis of bipolar I o...

384 participants
Intra-Cellular Therapies, Inc.
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RecruitingLittle Rock, ARNCT06462612

Study of Lumateperone in the Treatment of Patients With Bipolar Mania

This is a multicenter, randomized, double-blind, placebo-controlled, study in the acute treatment of patients with a diagnosis of bipolar I disorder with manic episodes or manic episodes with mixed fe...

350 participants
Intra-Cellular Therapies, Inc.
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RecruitingLittle Rock, ARNCT06929273

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

This is a phase 3, open-label extension study to assess the long-term safety of KarXT for the treatment of mania or mania with mixed features in Bipolar-I disorder (BP-I) The primary objective of the...

300 participants
Bristol-Myers Squibb
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RecruitingLittle Rock, ARNCT06951698

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder

The purpose of this study is to evaluate the efficacy and safety of KarXT for the treatment of manic episodes in Bipolar-I Disorder...

274 participants
Bristol-Myers Squibb
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RecruitingLittle Rock, ARNCT06951711

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)

This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, inpatient study in participants with bipolar disorder experiencing an acute episode of mania or mania with mixed features....

274 participants
Bristol-Myers Squibb
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RecruitingLittle Rock, ARNCT07046494

Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Bipolar I Disorder

This is a clinical research study for an investigational drug called RAP-219 in participants with bipolar I disorder. This study is being conducted to determine if RAP-219 is safe and effective in par...

224 participants
Rapport Therapeutics Inc.
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RecruitingLittle Rock, ARNCT06656416

ALTO-100 in Bipolar Disorder With Depression (BD-D)

The purpose of this study is to assess antidepressant efficacy differences between ALTO-100 and placebo during the Double-Blind period in patients with bipolar disorder I or II with current major depr...

200 participants
Alto Neuroscience
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About Bipolar Disorder Clinical Trials in Little Rock

Bipolar disorder is a mental health condition marked by extreme mood swings including emotional highs (mania or hypomania) and lows (depression). It affects about 2.8% of adults in the U.S. Treatment typically involves mood stabilizers, antipsychotics, and psychotherapy.

There are currently 8 bipolar disorder clinical trials recruiting participants in Little Rock, AR. These studies are seeking a combined 2,406 participants. Research is being sponsored by Xenon Pharmaceuticals Inc., Intra-Cellular Therapies, Inc., Bristol-Myers Squibb and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Bipolar Disorder Clinical Trials in Little Rock — FAQ

Are there bipolar disorder clinical trials in Little Rock?

Yes, there are 8 bipolar disorder clinical trials currently recruiting in Little Rock, AR. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Little Rock?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Little Rock research site will contact you about next steps.

Are clinical trials in Little Rock free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Little Rock studies also compensate for your time and travel.

What bipolar disorder treatments are being tested?

The 8 active trials in Little Rock are testing new therapies including novel drugs, biologics, and treatment approaches for bipolar disorder.

Data updated March 2, 2026 from ClinicalTrials.gov