10 Bipolar Disorder Clinical Trials in Little Rock, AR (2026)

Q: How do I join a clinical trial in Little Rock?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Little Rock research site will contact you.

Recruiting Bipolar Disorder Studies in Little Rock

NCT06929273Recruiting

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

This is a phase 3, open-label extension study to assess the long-term safety of KarXT for the treatment of mania or mania with mixed features in Bipolar-I disorder (BP-I) The primary objective of the...

Little Rock, ARPHASE3450 participantsBristol-Myers Squibb

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NCT07140913Recruiting

A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine

The purpose of this study is to evaluate the efficacy and safety of adjunctive KarXT for the treatment of mania in participants with Bipolar-I Disorder....

Little Rock, ARPHASE3424 participantsBristol-Myers Squibb

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NCT07172516Recruiting

A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)

X-CEED is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of azetukalner in adult participants diagnosed with bipolar I or II disorder wh...

Little Rock, ARPHASE3400 participantsXenon Pharmaceuticals Inc.

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NCT06372964Recruiting

Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients

This is a multicenter, randomized, double-blind, placebo-controlled study in pediatric patients who are experiencing major depressive episodes (MDEs) associated with a primary diagnosis of bipolar I o...

Little Rock, ARPHASE3384 participantsIntra-Cellular Therapies, Inc.

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NCT06462612Recruiting

Study of Lumateperone in the Treatment of Patients With Bipolar Mania

This is a multicenter, randomized, double-blind, placebo-controlled, study in the acute treatment of patients with a diagnosis of bipolar I disorder with manic episodes or manic episodes with mixed fe...

Little Rock, ARPHASE3350 participantsIntra-Cellular Therapies, Inc.

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NCT07494305Recruiting

Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.

Phase II study for patients with Bipolar 1 Disorder experiencing major depressive episode. Patient eligible for enrollment will be randomized (like flipping a coin) to either active drug (LB-102 or pl...

Little Rock, ARPHASE2320 participantsLB Pharmaceuticals Inc.

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NCT06951711Recruiting

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)

This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, inpatient study in participants with bipolar disorder experiencing an acute episode of mania or mania with mixed features....

Little Rock, ARPHASE3274 participantsBristol-Myers Squibb

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NCT06951698Recruiting

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder

The purpose of this study is to evaluate the efficacy and safety of KarXT for the treatment of manic episodes in Bipolar-I Disorder...

Little Rock, ARPHASE3274 participantsBristol-Myers Squibb

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NCT07046494Recruiting

Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Bipolar I Disorder

This is a clinical research study for an investigational drug called RAP-219 in participants with bipolar I disorder. This study is being conducted to determine if RAP-219 is safe and effective in par...

Little Rock, ARPHASE2250 participantsRapport Therapeutics Inc.

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NCT06656416Recruiting

ALTO-100 in Bipolar Disorder With Depression (BD-D)

The purpose of this study is to assess antidepressant efficacy differences between ALTO-100 and placebo during the Double-Blind period in patients with bipolar disorder I or II with current major depr...

Little Rock, ARPHASE2200 participantsAlto Neuroscience

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About Bipolar Disorder Clinical Trials in Little Rock

Bipolar disorder is a mental health condition marked by extreme mood swings including emotional highs (mania or hypomania) and lows (depression). It affects about 2.8% of adults in the U.S. Treatment typically involves mood stabilizers, antipsychotics, and psychotherapy.

There are currently 10 bipolar disorder clinical trials recruiting participants in Little Rock, AR. These studies are seeking a combined 3,326 participants. Research is being sponsored by Bristol-Myers Squibb, Xenon Pharmaceuticals Inc., Intra-Cellular Therapies, Inc. and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Bipolar Disorder Clinical Trials in Little Rock — FAQ

Are there bipolar disorder clinical trials in Little Rock?

Yes, there are 10 bipolar disorder clinical trials currently recruiting in Little Rock, AR. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Little Rock?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Little Rock research site will contact you about next steps.

Are clinical trials in Little Rock free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Little Rock studies also compensate for your time and travel.

What bipolar disorder treatments are being tested?

The 10 active trials in Little Rock are testing new therapies including novel drugs, biologics, and treatment approaches for bipolar disorder.

Data updated July 18, 2026 from ClinicalTrials.gov