Little Rock, AR7 Active Studies

Head and Neck Cancer Clinical Trials in Little Rock, AR

Find 7 actively recruiting head and neck cancer clinical trials in Little Rock, AR. Connect with local research sites and explore new treatment options.

7
Active Trials
4
Sponsors
2,923
Enrolling

Recruiting Head and Neck Cancer Studies in Little Rock

RecruitingLittle Rock, ARNCT05050162

Comparing Cisplatin Every Three Weeks to Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer

This phase II/III trial compares whether cisplatin given weekly with radiation therapy is better tolerated than cisplatin given every three weeks with radiation therapy for the treatment of head and n...

1,714 participants
NRG Oncology
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RecruitingLittle Rock, ARNCT01810913

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

This phase II/III trial studies how well radiation therapy works when given together with cisplatin, docetaxel, cetuximab, and/or atezolizumab after surgery in treating patients with high-risk stage I...

613 participants
National Cancer Institute (NCI)
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RecruitingLittle Rock, ARNCT04671667

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

This phase II trial studies the effect of pembrolizumab alone compared to the usual approach (chemotherapy \[cisplatin and carboplatin\] plus radiation therapy) after surgery in treating patients with...

188 participants
National Cancer Institute (NCI)
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RecruitingLittle Rock, ARNCT06589804

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

This phase III trial compares the effect of adding cetuximab to pembrolizumab versus pembrolizumab alone in treating patients with head and neck squamous cell carcinoma (HNSCC) that has come back afte...

158 participants
National Cancer Institute (NCI)
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RecruitingLittle Rock, ARNCT05952934

Candida Therapeutic Vaccine in Head and Neck Cancer Patients to Reduce Recurrence

This is a Phase II randomized, double-blind, placebo controlled, multi-site study of Candin. It is designed to show the efficacy and safety of a 7-dose regimen of Candin over a two-year period in term...

100 participants
University of Arkansas
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RecruitingLittle Rock, ARNCT06457503

A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer

This study aims to investigate toripalimab with chemotherapy in participants with nasopharyngeal cancer....

100 participants
Coherus Oncology, Inc.
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RecruitingLittle Rock, ARNCT06064097

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

This phase II trial tests effects of nivolumab in combination with chemotherapy drugs prior to radiation therapy patients with nasopharyngeal carcinoma (NPC). Immunotherapy with monoclonal antibodies,...

50 participants
National Cancer Institute (NCI)
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About Head and Neck Cancer Clinical Trials in Little Rock

Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.

There are currently 7 head and neck cancer clinical trials recruiting participants in Little Rock, AR. These studies are seeking a combined 2,923 participants. Research is being sponsored by NRG Oncology, National Cancer Institute (NCI), University of Arkansas and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Head and Neck Cancer Clinical Trials in Little Rock — FAQ

Are there head and neck cancer clinical trials in Little Rock?

Yes, there are 7 head and neck cancer clinical trials currently recruiting in Little Rock, AR. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Little Rock?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Little Rock research site will contact you about next steps.

Are clinical trials in Little Rock free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Little Rock studies also compensate for your time and travel.

What head and neck cancer treatments are being tested?

The 7 active trials in Little Rock are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.

Data updated March 2, 2026 from ClinicalTrials.gov