7 Head and Neck Cancer Clinical Trials in Little Rock, AR (2026)

Q: How do I join a clinical trial in Little Rock?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Little Rock research site will contact you.

Recruiting Head and Neck Cancer Studies in Little Rock

NCT01810913Recruiting

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

This phase II/III trial studies how well radiation therapy works when given together with cisplatin, docetaxel, cetuximab, and/or atezolizumab after surgery in treating patients with high-risk stage I...

Little Rock, ARPHASE2613 participantsNational Cancer Institute (NCI)

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NCT02734537Recruiting

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

This phase II trial studies how well radiation therapy with or without cisplatin works in treating patients with stage III-IVA squamous cell carcinoma of the head and neck who have undergone surgery. ...

Little Rock, ARPHASE2189 participantsECOG-ACRIN Cancer Research Group

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NCT04671667Recruiting

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

This phase II trial studies the effect of pembrolizumab alone compared to the usual approach (chemotherapy \[cisplatin and carboplatin\] plus radiation therapy) after surgery in treating patients with...

Little Rock, ARPHASE2188 participantsNational Cancer Institute (NCI)

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NCT06589804Recruiting

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

This phase III trial compares the effect of adding cetuximab to pembrolizumab versus pembrolizumab alone in treating patients with head and neck squamous cell carcinoma (HNSCC) that has come back afte...

Little Rock, ARPHASE3158 participantsNational Cancer Institute (NCI)

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NCT05952934Recruiting

Candida Therapeutic Vaccine in Head and Neck Cancer Patients to Reduce Recurrence

This is a Phase II randomized, double-blind, placebo controlled, multi-site study of Candin. It is designed to show the efficacy and safety of a 7-dose regimen of Candin over a two-year period in term...

Little Rock, ARPHASE2100 participantsUniversity of Arkansas

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NCT06457503Recruiting

A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer

This study aims to investigate toripalimab with chemotherapy in participants with nasopharyngeal cancer....

Little Rock, ARPHASE4100 participantsCoherus Oncology, Inc.

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NCT06064097Recruiting

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

This phase II trial tests effects of nivolumab in combination with chemotherapy drugs prior to radiation therapy patients with nasopharyngeal carcinoma (NPC). Immunotherapy with monoclonal antibodies,...

Little Rock, ARPHASE250 participantsNational Cancer Institute (NCI)

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About Head and Neck Cancer Clinical Trials in Little Rock

Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.

There are currently 7 head and neck cancer clinical trials recruiting participants in Little Rock, AR. These studies are seeking a combined 1,398 participants. Research is being sponsored by National Cancer Institute (NCI), ECOG-ACRIN Cancer Research Group, University of Arkansas and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Head and Neck Cancer Clinical Trials in Little Rock — FAQ

Are there head and neck cancer clinical trials in Little Rock?

Yes, there are 7 head and neck cancer clinical trials currently recruiting in Little Rock, AR. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Little Rock?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Little Rock research site will contact you about next steps.

Are clinical trials in Little Rock free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Little Rock studies also compensate for your time and travel.

What head and neck cancer treatments are being tested?

The 7 active trials in Little Rock are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.

Data updated July 17, 2026 from ClinicalTrials.gov