29 Rheumatoid Arthritis Clinical Trials in Little Rock, AR (2026)

Q: Are there rheumatoid arthritis clinical trials in Little Rock?

Yes, there are 29 rheumatoid arthritis clinical trials currently recruiting in Little Rock, AR.

Q: How do I join a clinical trial in Little Rock?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Little Rock research site will contact you.

Q: Are clinical trials in Little Rock free?

Yes, clinical trial participation is always free. Study-related treatments, medical tests, and doctor visits are provided at no cost.

Recruiting Rheumatoid Arthritis Studies in Little Rock

NCT00231400Recruiting

Pompe Disease Registry Protocol

The Pompe Registry is a global, multicenter, international, longitudinal, observational, and voluntary program for patients with Pompe disease, designed to track the disease's natural history and outc...

Little Rock, AR2,000 participantsGenzyme, a Sanofi Company

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NCT05589714Recruiting

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

This is an international, multicenter study with two components: Registry * A standardized genetic screening and a prospective, standardized, cross-sectional clinical data collection * Enrollment is...

Little Rock, AR1,500 participantsJaeb Center for Health Research

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NCT06066502Recruiting

Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome

The goal of this interventional study is to compare standard mechanical ventilation to a lung-stress oriented ventilation strategy in patients with Acute Respiratory Distress Syndrome (ARDS). Particip...

Little Rock, ARPHASE31,100 participantsBeth Israel Deaconess Medical Center

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NCT05125302Recruiting

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

Migraine is a common neurological disorder typically characterized by attacks of throbbing, moderate to severe headache, often associated with nausea, vomiting, and sensitivity to light and sound. Mig...

Little Rock, ARPHASE31,059 participantsAbbVie

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NCT05958342Recruiting

CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial

The CAlcium and VAsopressin following Injury Early Resuscitation (CAVALIER) Trial is a proposed 4 year, double-blind, mutli-center, prehospital and early in hospital phase randomized trial designed to...

Little Rock, ARPHASE21,050 participantsJason Sperry

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NCT06070350Recruiting

Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children

The MATIC-2 is a multicenter clinical trial enrolling children who are less than 18 years of age with hemorrhagic shock potentially needing significant blood transfusion. The primary objective of the...

Little Rock, ARPHASE31,000 participantsPhilip Spinella

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NCT07018700Recruiting

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic Migraine

In this clinical trial, participants with episodic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine d...

Little Rock, ARPHASE3990 participantsMerz Therapeutics GmbH

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NCT05354141Recruiting

Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)

To evaluate the safety and efficacy of intravenous (IV) administration of bone marrow mesenchymal stem cell derived extracellular vesicles (EVs), ExoFlo, versus placebo for the treatment of hospitaliz...

Little Rock, ARPHASE3970 participantsDirect Biologics, LLC

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NCT07018713Recruiting

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine

In this clinical trial, participants with chronic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine da...

Little Rock, ARPHASE3780 participantsMerz Therapeutics GmbH

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NCT06994442Recruiting

Optimizing Pain Treatment in Children On Mechanical Ventilation

In this clinical trial, investigators want to learn more about using non-opioid pain medications for children with acute respiratory failure. Right now, doctors give these children opioids to help wit...

Little Rock, ARPHASE3644 participantsWeill Medical College of Cornell University

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NCT06625060Recruiting

A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults

A migraine is a headache with severe throbbing pain or a pulsating sensation, usually on one side of the head. It is often accompanied by feeling or being sick and a sensitivity to bright lights and s...

Little Rock, ARPHASE2641 participantsIpsen

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NCT06701903Recruiting

Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder

This is a multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy, safety, and tolerability of ITI-1284 as monotherapy treatment in patients meeting Diagnostic and Stati...

Little Rock, ARPHASE2570 participantsIntra-Cellular Therapies, Inc.

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NCT07218380Recruiting

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

The purpose of this study is to test a new medicine, vepugratinib, in comparison with placebo, to see if it is safe and can help people with a bladder cancer that is advanced or has spread. Vepugrati...

Little Rock, ARPHASE3450 participantsEli Lilly and Company

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NCT05711394Recruiting

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

A migraine is a moderate to severe headache on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea, vomiting, sensitivity to light and sound, or other sy...

Little Rock, ARPHASE3450 participantsAbbVie

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NCT06810505Recruiting

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

Migraine is a disease that most often causes moderate to severe headache on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea, vomiting, sensitivity to...

Little Rock, ARPHASE3420 participantsAbbVie

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NCT06500455Recruiting

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

This phase III trial compares the effectiveness of fractionated stereotactic radiosurgery (FSRS) to usual care stereotactic radiosurgery (SRS) in treating patients with cancer that has spread from whe...

Little Rock, ARPHASE3269 participantsNRG Oncology

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NCT06872125Recruiting

A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome

The purpose of the study is to evaluate the efficacy, safety, and tolerability of zorevunersen in Patients with Dravet syndrome....

Little Rock, ARPHASE3170 participantsStoke Therapeutics, Inc

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NCT06660394Recruiting

A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)

This (DEEp SEA Study) is a double-blind, randomized, placebo-controlled, multicenter study to investigate the efficacy, safety, and tolerability of LP352 in the treatment of seizures in children and a...

Little Rock, ARPHASE3160 participantsLongboard Pharmaceuticals

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NCT06598943Recruiting

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

The main purpose of this study is to determine the safety and efficacy of eltrekibart and mirikizumab in adult participants with moderately to severely active ulcerative colitis (UC)....

Little Rock, ARPHASE2140 participantsEli Lilly and Company

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NCT05099003Recruiting

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

This phase I/II trial tests the safety, side effects, and best dose of selinexor given in combination with standard radiation therapy in treating children and young adults with newly diagnosed diffuse...

Little Rock, ARPHASE1132 participantsNational Cancer Institute (NCI)

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NCT05932680Recruiting

Limited-duration Teclistamab

This is a single-arm, non-inferiority study in which patients who have achieved a very good partial response (VGPR) or better, according to International Myeloma Working Group (IMWG) response criteria...

Little Rock, ARPHASE275 participantsAbramson Cancer Center at Penn Medicine

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NCT05491525Recruiting

A Study of Vibegron in Pediatric Participants 2 Years to Less Than (<) 18 Years of Age With NDO and on CIC

The purpose of this study is to evaluate the safety, efficacy, and PK of vibegron in pediatric participants with NDO who are regularly using CIC...

Little Rock, ARPHASE271 participantsUrovant Sciences GmbH

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NCT07489651Recruiting

RE104 Safety and Efficacy Study in Generalized Anxiety Disorder

The purpose of this study is to determine if treatment with a single dose of RE104 for Injection reduces anxiety symptoms in participants with Generalized Anxiety Disorder (GAD) as compared to placebo...

Little Rock, ARPHASE264 participantsReunion Neuroscience Inc

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NCT07115004Recruiting

Study to Evaluate Subcutaneous (SC) VGA039 in Patients With Von Willebrand Disease (VWD)

This is a phase 3 study that will evaluate subcutaneous (SC) VGA039 in patients with von Willebrand Disease (VWD)...

Little Rock, ARPHASE360 participantsVega Therapeutics, Inc

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NCT05287126Recruiting

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment of moderately to severely active ulcerative colitis in adolescents (≥ 12 years ...

Little Rock, ARPHASE236 participantsPfizer

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NCT05383274Recruiting

Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters

Single-arm, prospective study assessing semen quality after treatment with the Optilume Urethral DCB in men between 22 and 65 years of age....

Little Rock, ARPHASE434 participantsUrotronic Inc.

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NCT06560918Recruiting

Self-efficacy-based Auditory Rehabilitation With Over-the-Counter Hearing Aids

This goal of this study is to learn if a new audiology treatment process called the self-efficacy-based auditory rehabilitation (SEBAR) can improve confidence and success with over-the-counter (OTC) h...

Little Rock, ARNA27 participantsUniversity of Arkansas

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NCT06422923Recruiting

A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)

This is a multicenter, single arm, open label clinical trial that is designed to test the safety and preliminary efficacy of single administration inhibitory nerve cells called interneurons (NRTX-1001...

Little Rock, ARPHASE110 participantsNeurona Therapeutics

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NCT07674953Recruiting

How Different Levels of CPAP Affect Oxygen Delivery and Lung Expansion in Preterm Infants

With this study, it is expected to learn more about preterm babies on breathing support with nasal continuous positive airway pressure (nCPAP). To gain more information on how much oxygen is actually ...

Little Rock, ARNA10 participantsUniversity of Arkansas

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About Rheumatoid Arthritis Clinical Trials in Little Rock

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting approximately 1.3 million Americans, where the immune system mistakenly attacks joint linings, causing painful swelling, bone erosion, and joint deformity. Early diagnosis and treatment are critical to prevent irreversible damage. Current standard treatments include methotrexate and other DMARDs, TNF inhibitors (etanercept, infliximab), IL-6 inhibitors (tocilizumab), T-cell costimulation modulators (abatacept), and JAK inhibitors (tofacitinib, baricitinib). Clinical trials are now exploring next-generation targeted therapies, dual-pathway inhibitors, and treatment strategies aimed at achieving sustained remission rather than just symptom control. Patients with inadequate response to conventional DMARDs or biologics are commonly eligible for enrollment.

There are currently 29 rheumatoid arthritis clinical trials recruiting participants in Little Rock, AR. These studies are seeking a combined 14,882 participants. Research is being sponsored by Genzyme, a Sanofi Company, Jaeb Center for Health Research, Beth Israel Deaconess Medical Center and 21 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Rheumatoid Arthritis Clinical Trials in Little Rock — FAQ

Are there rheumatoid arthritis clinical trials in Little Rock?

Yes, there are 29 rheumatoid arthritis clinical trials currently recruiting in Little Rock, AR. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Little Rock?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Little Rock research site will contact you about next steps.

Are clinical trials in Little Rock free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Little Rock studies also compensate for your time and travel.

What rheumatoid arthritis treatments are being tested?

The 29 active trials in Little Rock are testing new therapies including novel drugs, biologics, and treatment approaches for rheumatoid arthritis.

Data updated July 19, 2026 from ClinicalTrials.gov