Los Angeles, CA4 Active Studies

Esophageal Cancer Clinical Trials in Los Angeles, CA

Find 4 actively recruiting esophageal cancer clinical trials in Los Angeles, CA. Connect with local research sites and explore new treatment options.

4
Active Trials
1
Sponsors
900
Enrolling

Recruiting Esophageal Cancer Studies in Los Angeles

RecruitingLos Angeles, CANCT06356311

A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015)

This study will compare how safe and effective sacituzumab tirumotecan is versus the treatment of physician's choice (TPC) in participants with advanced/metastatic gastroesophageal adenocarcinoma. The...

450 participants
Merck Sharp & Dohme LLC
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RecruitingLos Angeles, CANCT05319730

A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)

This is a Phase 1/2, multicenter, randomized, open-label umbrella platform study to evaluate the safety and efficacy of investigational agents with or without pembrolizumab and/or chemotherapy, for th...

230 participants
Merck Sharp & Dohme LLC
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RecruitingLos Angeles, CANCT06469944

Substudy 06C: A Study of Sacituzumab Tirumotecan (MK-2870) With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

This is a phase 1/2, multicenter, open-label umbrella platform study that will evaluate the safety and tolerability of sacituzumab tirumotecan with pembrolizumab and fluoropyrimidine chemotherapy for ...

130 participants
Merck Sharp & Dohme LLC
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RecruitingLos Angeles, CANCT06445972

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

This is a phase 1/2 multicenter, open-label umbrella platform study that will evaluate the safety and efficacy of sacituzumab tirumotecan (MK-2870) plus paclitaxel versus ramucirumab plus paclitaxel, ...

90 participants
Merck Sharp & Dohme LLC
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About Esophageal Cancer Clinical Trials in Los Angeles

Esophageal cancer occurs in the esophagus, the tube connecting the throat to the stomach. The two main types are squamous cell carcinoma and adenocarcinoma. Treatment may include surgery, chemotherapy, radiation, and immunotherapy.

There are currently 4 esophageal cancer clinical trials recruiting participants in Los Angeles, CA. These studies are seeking a combined 900 participants. Research is being sponsored by Merck Sharp & Dohme LLC. Clinical trial participation is free and participants receive study-related medical care at no cost.

Esophageal Cancer Clinical Trials in Los Angeles — FAQ

Are there esophageal cancer clinical trials in Los Angeles?

Yes, there are 4 esophageal cancer clinical trials currently recruiting in Los Angeles, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Los Angeles?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Angeles research site will contact you about next steps.

Are clinical trials in Los Angeles free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Los Angeles studies also compensate for your time and travel.

What esophageal cancer treatments are being tested?

The 4 active trials in Los Angeles are testing new therapies including novel drugs, biologics, and treatment approaches for esophageal cancer.

Data updated March 2, 2026 from ClinicalTrials.gov