Los Angeles, CALIFORNIA6 Active Studies

Liver Cancer Clinical Trials in Los Angeles, CALIFORNIA

Find 6 actively recruiting liver cancer clinical trials in Los Angeles, CALIFORNIA. Connect with local research sites and explore new treatment options.

6
Active Trials
6
Sponsors
6,092
Enrolling

Recruiting Liver Cancer Studies in Los Angeles

RecruitingLos Angeles, CALIFORNIANCT06084234

National Liver Cancer Screening Trial

The National Liver Cancer Screening Trial is an adaptive randomized phase IV Trial comparing ultrasound-based versus biomarker-based screening in 5500 patients with cirrhosis from any etiology or pati...

5,500 participants
University of Texas Southwestern Medical Center
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RecruitingLos Angeles, CALIFORNIANCT05775159

Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary Cancer

GEMINI-Hepatobiliary study will assess the efficacy, safety and tolerability of novel immunomodulators alone and in combination with other anticancer drugs in participants with specified advanced soli...

260 participants
AstraZeneca
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RecruitingLos Angeles, CALIFORNIANCT05440708

A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

The primary objectives of Cohort A Phase 1b are to evaluate the safety and tolerability of TTI-101 orally administered as a single agent to participants with locally advanced or metastatic, and unrese...

178 participants
Tvardi Therapeutics, Incorporated
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RecruitingLos Angeles, CALIFORNIANCT06679985

A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular Carcinoma

The main goals of this study are to evaluate the safety and efficacy of casdozokitug in combination with toripalimab plus bevacizumab and to define a recommended dose for casdozokitug in combination w...

72 participants
Coherus Oncology, Inc.
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RecruitingLos Angeles, CALIFORNIANCT06501625

Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation

The objective of this study is to investigate the safety, tolerability and preliminary activity of ivosidenib in combination with durvalumab and gemcitabine/cisplatin as first-line therapy in particip...

52 participants
Institut de Recherches Internationales Servier
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RecruitingLos Angeles, CALIFORNIANCT06096779

A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-Pugh B7 and B8 Cirrhosis

The purpose of this study is to assess the safety of atezolizumab and bevacizumab, or atezolizumab alone, as first-line treatment in participants with unresectable, locally advanced or metastatic hepa...

30 participants
Genentech, Inc.
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About Liver Cancer Clinical Trials in Los Angeles

Liver cancer most commonly presents as hepatocellular carcinoma (HCC) and is often associated with chronic liver disease or hepatitis. It is one of the fastest-growing causes of cancer death. Treatment options include surgery, liver transplant, ablation, and systemic therapies.

There are currently 6 liver cancer clinical trials recruiting participants in Los Angeles, CALIFORNIA. These studies are seeking a combined 6,092 participants. Research is being sponsored by University of Texas Southwestern Medical Center, AstraZeneca, Tvardi Therapeutics, Incorporated and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Liver Cancer Clinical Trials in Los Angeles — FAQ

Are there liver cancer clinical trials in Los Angeles?

Yes, there are 6 liver cancer clinical trials currently recruiting in Los Angeles, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Los Angeles?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Angeles research site will contact you about next steps.

Are clinical trials in Los Angeles free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Los Angeles studies also compensate for your time and travel.

What liver cancer treatments are being tested?

The 6 active trials in Los Angeles are testing new therapies including novel drugs, biologics, and treatment approaches for liver cancer.

Data updated March 2, 2026 from ClinicalTrials.gov