Recruiting Major Depressive Disorder Studies in Los Angeles
Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD
Efficacy, Safety, and Tolerability of two administrations of COMP360 in participants with treatment-resistant depression (TRD)...
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
X-NOVA2 is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of azetukalner as a monotherapy in adult participants ...
Study of ALTO-300 in MDD
The purpose of this study is to determine efficacy differences between ALTO-300 and placebo, used adjunctively to an antidepressant, related to patient characteristics....
Psilocybin for Major Depressive Disorder (MDD)
Approximately 240 eligible adult participants (≥18 years old) who meet Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR) criteria for Major Depressive Disorder (MDD) will be enrolled. P...
NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
The study will evaluate the efficacy of NBI-1065845 compared with placebo as an adjunctive treatment in participants with MDD on improving symptoms of depression....
GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder
The goal of this clinical trial is to learn if GATE-251 works to treat depression in adults. It will also learn about the safety of GATE-251. The main questions it aims to answer are: Does GATE-251 r...
About Major Depressive Disorder Clinical Trials in Los Angeles
Major depressive disorder (MDD) is a severe form of depression characterized by persistent sadness, loss of interest, and impaired daily functioning. Treatment-resistant depression (TRD) affects patients who do not respond to standard therapies. Novel treatments like ketamine, psilocybin, and neuromodulation are being studied.
There are currently 6 major depressive disorder clinical trials recruiting participants in Los Angeles, CALIFORNIA. These studies are seeking a combined 1,943 participants. Research is being sponsored by COMPASS Pathways, Xenon Pharmaceuticals Inc., Alto Neuroscience and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.
Major Depressive Disorder Clinical Trials in Los Angeles — FAQ
Are there major depressive disorder clinical trials in Los Angeles?
Yes, there are 6 major depressive disorder clinical trials currently recruiting in Los Angeles, CALIFORNIA. Browse the studies on this page to find one that fits.
How do I join a clinical trial in Los Angeles?
Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Angeles research site will contact you about next steps.
Are clinical trials in Los Angeles free?
Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Los Angeles studies also compensate for your time and travel.
What major depressive disorder treatments are being tested?
The 6 active trials in Los Angeles are testing new therapies including novel drugs, biologics, and treatment approaches for major depressive disorder.
Data updated March 2, 2026 from ClinicalTrials.gov