Los Angeles, CALIFORNIA6 Active Studies

Myelofibrosis Clinical Trials in Los Angeles, CALIFORNIA

Find 6 actively recruiting myelofibrosis clinical trials in Los Angeles, CALIFORNIA. Connect with local research sites and explore new treatment options.

6
Active Trials
5
Sponsors
1,958
Enrolling

Recruiting Myelofibrosis Studies in Los Angeles

RecruitingLos Angeles, CALIFORNIANCT06479135

Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

This clinical trial is evaluating whether addition of navtemadlin to ruxolitinib treatment will provide more clinical benefit than ruxolitinib alone for patients with Myelofibrosis who have a suboptim...

600 participants
Kartos Therapeutics, Inc.
View Study Details
RecruitingLos Angeles, CALIFORNIANCT03165734

A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis

This study (study ID PAC203 North America; PAC303 ex-North America) is evaluating 200 mg BID of pacritinib compared to physician's choice (P/C) therapy in patients with MF and severe thrombocytopenia ...

399 participants
Swedish Orphan Biovitrum
View Study Details
RecruitingLos Angeles, CALIFORNIANCT03662126

KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment

This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with myelofibrosis (MF) who no longer benefit from treatment with a JAK inhibitor. Inhibition...

385 participants
Kartos Therapeutics, Inc.
View Study Details
RecruitingLos Angeles, CALIFORNIANCT04576156

A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment

The purpose of the study is to evaluate the overall survival of participants treated with imetelstat compared to best available therapy with intermediate-2 or high-risk Myelofibrosis (MF) who are rela...

320 participants
Geron Corporation
View Study Details
RecruitingLos Angeles, CALIFORNIANCT04176198

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

This study is a Phase 1/2, multicenter, dose-escalation, open-label trial to assess safety, tolerability, pharmacokinetics and pharmacodynamics of nuvisertib (TP-3654) in patients with intermediate or...

240 participants
Sumitomo Pharma America, Inc.
View Study Details
RecruitingLos Angeles, CALIFORNIANCT05467800

Study of Canakinumab in Patients With Myelofibrosis

This is an open label, multicenter, phase 2 trial of Canakinumab in patients with primary myelofibrosis (PMF), post essential thrombocythemia/polycythemia vera related MF (Post ET/PV MF). Eligible pat...

14 participants
John Mascarenhas
View Study Details

About Myelofibrosis Clinical Trials in Los Angeles

Myelofibrosis is a serious bone marrow disorder that disrupts normal blood cell production, leading to extensive scarring in the bone marrow. It can cause severe anemia, weakness, and an enlarged spleen. Treatment includes JAK inhibitors, blood transfusions, and stem cell transplant.

There are currently 6 myelofibrosis clinical trials recruiting participants in Los Angeles, CALIFORNIA. These studies are seeking a combined 1,958 participants. Research is being sponsored by Kartos Therapeutics, Inc., Swedish Orphan Biovitrum, Geron Corporation and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Myelofibrosis Clinical Trials in Los Angeles — FAQ

Are there myelofibrosis clinical trials in Los Angeles?

Yes, there are 6 myelofibrosis clinical trials currently recruiting in Los Angeles, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Los Angeles?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Angeles research site will contact you about next steps.

Are clinical trials in Los Angeles free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Los Angeles studies also compensate for your time and travel.

What myelofibrosis treatments are being tested?

The 6 active trials in Los Angeles are testing new therapies including novel drugs, biologics, and treatment approaches for myelofibrosis.

Data updated March 2, 2026 from ClinicalTrials.gov