16 Advanced Solid Tumors Clinical Trials in Louisville, KY (2026)

Q: How do I join a clinical trial in Louisville?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Louisville research site will contact you.

Recruiting Advanced Solid Tumors Studies in Louisville

NCT06635785Recruiting

Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

BIPAVE-001 is a Phase 1-2 study for evaluating the safety, pharmacokinetics (PK), and efficacy of AI-081 in solid tumors....

Louisville, KYPHASE1387 participantsOncoC4, Inc.

View Study Details

NCT06004245Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

This is a first-in-human, Phase I, open-label, multicenter, dose-escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary anti-tumo...

Louisville, KYPHASE1280 participantsVividion Therapeutics, Inc.

View Study Details

NCT06459973Recruiting

A Clinical Study of YL205 in Patients With Advanced Solid Tumors

This study is a multicenter, open-label, phase I/II study of YL205 in China to evaluate the safety, tolerability, PK characteristics and preliminary efficacy of YL205 in the following selected patient...

Louisville, KYPHASE1252 participantsMediLink Therapeutics (Suzhou) Co., Ltd.

View Study Details

NCT06219941Recruiting

AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2

The purpose of this study is to assess the safety, tolerability, efficacy, pharmacokinetics (PK), and immunogenicity of AZD0901 as monotherapy and in combination with anti-cancer agents in participant...

Louisville, KYPHASE2224 participantsAstraZeneca

View Study Details

NCT05719558Recruiting

A Study of ASP1002 in Adults for Treatment of Solid Tumors

The main aims of this study are: * To check the safety of ASP1002 in people with certain solid tumors. * To check if the people can tolerate ASP1002. * To find a suitable dose of ASP1002. This study ...

Louisville, KYPHASE1210 participantsAstellas Pharma Global Development, Inc.

View Study Details

NCT06060613Recruiting

Safety and Efficacy of OBX-115 in Advanced Solid Tumors

This is a study to investigate the safety and efficacy of an investigational OBX-115 regimen in adult participants with advanced solid tumors....

Louisville, KYPHASE1208 participantsObsidian Therapeutics, Inc.

View Study Details

NCT07169734Recruiting

A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetic, pharmacodynamic, preliminary anti-tumor activity, and to determine the recommended Phase II dose (RP2D) of the ALE.P...

Louisville, KYPHASE1180 participantsAlentis Therapeutics AG

View Study Details

NCT06747585Recruiting

A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors

Louisville, KYPHASE1170 participantsAlentis Therapeutics AG

View Study Details

NCT05270213Recruiting

Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors

RBS2418 (investigational product) is a specific immune modulator, working through ectonucleotide pyrophosphatase/phosphodiesterase I (ENPP1), designed to lead to anti-tumor immunity by increasing endo...

Louisville, KYPHASE1164 participantsRiboscience, LLC.

View Study Details

NCT06898450Recruiting

A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

The goal of this clinical trial is to learn if NDI-219216 is safe for patients, and if NDI-219216 might be a possible treatment for advanced solid tumors in the later phases of the study. The main qu...

Louisville, KYPHASE1134 participantsNimbus Wadjet, Inc.

View Study Details

NCT06028074Recruiting

Safety and Tolerability Study of GIM-122 in Subjects With Advanced Solid Malignancies

GIM-122 is a first-in-class, humanized immunoglobulin G1 kappa dual functioning monoclonal antibody (DFA). This phase 1 / 2 study plans to evaluate the safety, tolerability, pharmacokinetics and clini...

Louisville, KYPHASE1111 participantsGeorgiamune Inc

View Study Details

NCT04969315Recruiting

TT-10 (PORT-6) and TT-4 (PORT-7) as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors

The goal of this clinical trial is to evaluate TT-10, TT-4 and TT-10 + TT-4, (Dual Blockade) in participants with advanced selected solid tumors, who have failed or are not eligible for standard of ca...

Louisville, KYPHASE190 participantsPortage Biotech

View Study Details

NCT05635643Recruiting

Study of CHS-114 in Participants With Advanced Solid Tumors

This is a Phase 1, open-label, first-in-human, dose-escalation and expansion study of CHS-114, a monoclonal antibody that targets CCR8, as a monotherapy in patients with solid tumors....

Louisville, KYPHASE187 participantsCoherus Oncology, Inc.

View Study Details

NCT06352359Recruiting

Safety, Pharmacokinetics (PK), and Efficacy of ONC 841 in Advanced Solid Tumors

This is a Phase I/II open label study of intravenous (IV) infusion of ONC-841 as a single agent or in combination in patients with advanced/metastatic solid tumors. The study will evaluate seven dose ...

Louisville, KYPHASE172 participantsOncoC4, Inc.

View Study Details

NCT06750185Recruiting

Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors

This is a first-in-human (FIH), open-label, multiple-site, dose escalation study which will evaluate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of increasing doses of BNT317 i...

Louisville, KYPHASE139 participantsBioNTech SE

View Study Details

NCT05487170Recruiting

A Study of RNK05047 in Subjects With Advanced Solid Tumors/Diffuse Large B-cell Lymphoma (CHAMP-1)

This is a first in human, Phase 1/2 open-label multi-center, dose escalation and expansion study to evaluate the safety, tolerability, PK, PD and efficacy of RNK05047 when administered an intravenous ...

Louisville, KYPHASE132 participantsRanok Therapeutics (Hangzhou) Co., Ltd.

View Study Details

About Advanced Solid Tumors Clinical Trials in Louisville

Advanced solid tumors refer to cancers that have grown beyond the original site or spread to distant organs. Many clinical trials enroll patients with various types of advanced solid tumors to test novel therapies. These trials often investigate immunotherapy, targeted therapy, and combination approaches.

There are currently 16 advanced solid tumors clinical trials recruiting participants in Louisville, KY. These studies are seeking a combined 2,640 participants. Research is being sponsored by OncoC4, Inc., Vividion Therapeutics, Inc., MediLink Therapeutics (Suzhou) Co., Ltd. and 11 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Advanced Solid Tumors Clinical Trials in Louisville — FAQ

Are there advanced solid tumors clinical trials in Louisville?

Yes, there are 16 advanced solid tumors clinical trials currently recruiting in Louisville, KY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Louisville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Louisville research site will contact you about next steps.

Are clinical trials in Louisville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Louisville studies also compensate for your time and travel.

What advanced solid tumors treatments are being tested?

The 16 active trials in Louisville are testing new therapies including novel drugs, biologics, and treatment approaches for advanced solid tumors.

Data updated July 17, 2026 from ClinicalTrials.gov