5 Melanoma Clinical Trials in Louisville, KY (2026)

Q: How do I join a clinical trial in Louisville?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Louisville research site will contact you.

Recruiting Melanoma Studies in Louisville

NCT05727904Recruiting

Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

This is a Phase 3, multicenter, open-label, randomized, parallel group, treatment study to assess the efficacy and safety of lifileucel in combination with pembrolizumab compared with pembrolizumab al...

Louisville, KYPHASE3670 participantsIovance Biotherapeutics, Inc.

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NCT01638676Recruiting

A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients

The main purpose of this study is to evaluate the safety of Vemurafenib in combination with Metformin in melanoma patients. The phase II part of the study will also evaluate the clinical activity of t...

Louisville, KYPHASE155 participantsUniversity of Louisville

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NCT05361174Recruiting

A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

This is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma or advanced non-small-cell lung cancer (NSCLC)....

Louisville, KYPHASE153 participantsIovance Biotherapeutics, Inc.

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NCT04513028Recruiting

Beta Glucan's Effect on Pembrolizumab Immunologic Response in Stage III-IV Melanoma

The purpose of this study is to determine how beta-glucan affects the immune system in subjects with melanoma....

Louisville, KYNA30 participantsKelly McMasters

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NCT03842943Recruiting

Neoadjuvant Combination Immunotherapy for Stage III Melanoma

Determine safety and efficacy of pre-operative combination immunotherapy with Talimogene Laherparepvec (T-VEC)/Pembrolizumab given prior to complete lymph node dissection in resectable stage 3 cutaneo...

Louisville, KYPHASE228 participantsUniversity of Louisville

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About Melanoma Clinical Trials in Louisville

Melanoma is the most serious type of skin cancer, developing from the pigment-producing cells known as melanocytes. While less common than other skin cancers, melanoma is more likely to spread. Immunotherapy and targeted therapy have revolutionized melanoma treatment.

There are currently 5 melanoma clinical trials recruiting participants in Louisville, KY. These studies are seeking a combined 836 participants. Research is being sponsored by Iovance Biotherapeutics, Inc., University of Louisville, Kelly McMasters. Clinical trial participation is free and participants receive study-related medical care at no cost.

Melanoma Clinical Trials in Louisville — FAQ

Are there melanoma clinical trials in Louisville?

Yes, there are 5 melanoma clinical trials currently recruiting in Louisville, KY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Louisville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Louisville research site will contact you about next steps.

Are clinical trials in Louisville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Louisville studies also compensate for your time and travel.

What melanoma treatments are being tested?

The 5 active trials in Louisville are testing new therapies including novel drugs, biologics, and treatment approaches for melanoma.

Data updated July 17, 2026 from ClinicalTrials.gov