12 Spinal Muscular Atrophy Clinical Trials in Louisville, KY (2026)

Q: How do I join a clinical trial in Louisville?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Louisville research site will contact you.

Recruiting Spinal Muscular Atrophy Studies in Louisville

NCT06095583Recruiting

Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)

The Study is a Phase 3, randomized, three-arm, double-blind, placebo-controlled, multi-regional clinical research study to evaluate the safety and efficacy use of toripalimab alone or in combination w...

Louisville, KY756 participantsShanghai Junshi Bioscience Co., Ltd.

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NCT05005403Recruiting

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues...

Louisville, KY694 participantsAbbVie

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NCT07472517Recruiting

DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemotherapy

This study is open to adults with advanced small cell lung cancer (SCLC). The purpose of this study is to find out if a study medicine called obrixtamig plus standard treatment (atezolizumab, carbopla...

Louisville, KY670 participantsBoehringer Ingelheim

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NCT07037758Recruiting

A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)

The primary objective for dose exploration and dose expansion is to evaluate the safety and tolerability of tarlatamab in combination with AB248. The primary objective for dose exploration only is to...

Louisville, KY380 participantsAmgen

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NCT05142189Recruiting

Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer

This first-in-human (FIH) study for BNT116 aims to establish the safety profile and a safe dose for BNT116 monotherapy as well as for BNT116 in combination with approved medicinal products and/or in c...

Louisville, KY320 participantsBioNTech SE

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NCT00682032Recruiting

The Effect of Beta-glucan in Non-Small Cell Lung Cancer

The purpose of this study is to determine how beta-glucan affects the immune system in subjects with non-small cell lung cancer....

Louisville, KY300 participantsUniversity of Louisville

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NCT06324201Recruiting

The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.

Observational, multi-center, non-randomized, post-market study. This is a nested sub-study of the REAL AF Registry. Consecutive symptomatic drug refractory paroxysmal atrial fibrillation (PAF) patient...

Louisville, KY250 participantsHeart Rhythm Clinical and Research Solutions, LLC

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NCT04270591Recruiting

Assessment of Anti-tumor and Safety in Glumetinib in Patients With c-MET-positive Non-Small Cell Lung Cancer

Indication:Patients with Advanced c-MET-positive Non-Small Cell Lung Cancer Phase Ib (China only): Approximately 90 patients Phase Ⅱ (globally): Approximately 78 evaluable patients; addition of at...

Louisville, KY183 participantsHaihe Biopharma Co., Ltd.

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NCT06681220Recruiting

Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC

Randomized phase 2, multicenter, biomarker directed clinical trial with a safety lead-in to assess the efficacy of Stenoparib plus Temozolomide (TMZ) in relapsed Small Cell Lung Cancer patients. Parti...

Louisville, KY166 participantsVA Office of Research and Development

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NCT07407933Recruiting

A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors

This is a phase Ib/II, multicenter, open-label study of YL201 combined with atezolizumab. The study will include 2 parts. Part 1 of the study is a dose escalation in participants with previously untre...

Louisville, KY118 participantsMediLink Therapeutics (Suzhou) Co., Ltd.

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NCT06046495Recruiting

A Study of the Oral EGFR Inhibitor PLB1004 in Non-Small Cell Lung Cancer

This is a Phase I, multicenter, open-label, dose escalation and dose expansion study to assess the safety and pharmacokinetic profile of PLB1004, a mono-anilino-pyrimidine compound, given alone in NSC...

Louisville, KY81 participantsAvistone Biotechnology Co., Ltd.

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NCT07250958Recruiting

Dome-Only Aneurysm Coiling in Severe Aneurysmal Subarachnoid Hemorrhage

The DOME study is a clinical trial exploring a new treatment approach for patients who suffered a severe brain bleed due to an aneurysm....

Louisville, KY30 participantsUniversity of Louisville

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About Spinal Muscular Atrophy Clinical Trials in Louisville

Spinal muscular atrophy (SMA) is a genetic neuromuscular disorder that causes loss of motor neurons, leading to progressive muscle weakness and atrophy. It is the leading genetic cause of infant death. Revolutionary gene therapies and SMN-enhancing drugs have transformed treatment.

There are currently 12 spinal muscular atrophy clinical trials recruiting participants in Louisville, KY. These studies are seeking a combined 3,948 participants. Research is being sponsored by Shanghai Junshi Bioscience Co., Ltd., AbbVie, Boehringer Ingelheim and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Spinal Muscular Atrophy Clinical Trials in Louisville — FAQ

Are there spinal muscular atrophy clinical trials in Louisville?

Yes, there are 12 spinal muscular atrophy clinical trials currently recruiting in Louisville, KY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Louisville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Louisville research site will contact you about next steps.

Are clinical trials in Louisville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Louisville studies also compensate for your time and travel.

What spinal muscular atrophy treatments are being tested?

The 12 active trials in Louisville are testing new therapies including novel drugs, biologics, and treatment approaches for spinal muscular atrophy.

Data updated July 13, 2026 from ClinicalTrials.gov