23 Leukemia Clinical Trials in Memphis, TN (2026)

Q: How do I join a clinical trial in Memphis?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Memphis research site will contact you.

Recruiting Leukemia Studies in Memphis

NCT00730678Recruiting

Pharmacogenetic Determinants Of Treatment Response In Children

To investigate whether genetic polymorphisms in genes encoding proteins involved in the metabolism or effects of drugs or environmental agents influence the disposition or effects of these xenobiotic ...

Memphis, TN8,800 participantsSt. Jude Children's Research Hospital

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NCT03050268Recruiting

Familial Investigations of Childhood Cancer Predisposition

NOTE: This is a research study and is not meant to be a substitute for clinical genetic testing. Families may never receive results from the study or may receive results many years from the time they ...

Memphis, TN1,500 participantsSt. Jude Children's Research Hospital

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NCT06289673Recruiting

Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

The goal of this study is to provide sufficient therapy during the time a patients' B-cell Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LLy) risk category is being determined. The ter...

Memphis, TNPHASE4850 participantsSt. Jude Children's Research Hospital

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NCT06745882Recruiting

Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/ NSCLC

This is a non-registrational, cohort study enrolling eligible Black patients diagnosed with histologically or cytologically, advanced/metastatic NSCLC without known EGFR/ALK/ROS1 tumor mutations, and ...

Memphis, TNPHASE2318 participantsH. Lee Moffitt Cancer Center and Research Institute

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NCT07227597Recruiting

A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)

Researchers are looking for new ways to treat extensive-stage small cell lung cancer (ES-SCLC). ES-SCLC is a type of lung cancer that has spread throughout the lung, to the other lung, or to other par...

Memphis, TNPHASE1170 participantsMerck Sharp & Dohme LLC

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NCT07531095Recruiting

Study of Tarlatamab + ZL-1310 +/- Anti-programmed Death Ligand 1 (Anti-PD-L1) in Small Cell Lung Cancer (SCLC)

The primary objective of this trial is to evaluate the safety and tolerability of tarlatamab in combination with ZL-1310 with or without durvalumab and to determine the maximum tolerated combination d...

Memphis, TNPHASE1160 participantsAmgen

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NCT06533748Recruiting

Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma

This is a Phase II clinical trial testing the use of two antigen-directed therapies, inotuzumab and blinatumomab, as part of induction therapy for children and young adults with newly diagnosed B-cell...

Memphis, TNPHASE2128 participantsSt. Jude Children's Research Hospital

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NCT05763290Recruiting

Childhood Cancer Survivors' Affective Response to Exercise

The primary objective of this study is to assess the feasibility of administering the Personalized Single-Category Implicit Association Test (PSC-IAT) to young adult survivors of childhood cancer. Pa...

Memphis, TN125 participantsSt. Jude Children's Research Hospital

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NCT04318678Recruiting

CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)

The CD123-CAR T-cell therapy is a new treatment that is being investigated for treatment of AML/myelodysplastic syndrome (MDS), T- or B- acute lymphoblastic leukemia (ALL) or blastic plasmacytoid dend...

Memphis, TNPHASE1108 participantsSt. Jude Children's Research Hospital

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NCT06579469Recruiting

Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy

This study is being done to learn more about the short-term and long-term side effects of CAR-T cell therapy. Specifically, researchers want to know how often patients get infections, have delays in r...

Memphis, TN100 participantsSt. Jude Children's Research Hospital

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NCT06390319Recruiting

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

This is a clinical trial testing whether the addition of one of two chemotherapy agents, dasatinib or venetoclax, can improve outcomes for children and young adults with newly diagnosed T-cell acute l...

Memphis, TNPHASE2100 participantsSt. Jude Children's Research Hospital

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NCT07048535Recruiting

CAR T-cell Long-Term Follow-Up, Quality of Life and Adverse Reactions

To learn more about the long-term health in patients treated for B-Cell Acute Lymphoblastic Leukemia (B-ALL) with Cluster of Differentiation antigen 19 (CD19) -redirected chimeric antigen receptor (C...

Memphis, TN80 participantsSt. Jude Children's Research Hospital

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NCT07257419Recruiting

CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

The purpose of this study is to learn more about newer methods of transplanting blood cells donated by a partially matched family member to children with high-risk CD19 positive leukemia ALL. Primary...

Memphis, TNPHASE170 participantsSt. Jude Children's Research Hospital

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NCT06686472Recruiting

Evaluation of TL-925 for the Treatment of Allergic Conjunctivitis

In this prospective, Phase 2, randomized, double-masked, vehicle controlled study, approximately 66 eligible subjects will be randomized 1:1 to receive either TL-925 or placebo as topical ophthalmic e...

Memphis, TNPHASE266 participantsTelios Pharma, Inc.

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NCT04881240Recruiting

Study of CD19 Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia

This is a Phase I clinical study evaluating the safety and maximum tolerated dose of a novel CAR T-cell product: allogeneic memory (CD45RA- negative) T-cells expressing a CD19-specific CAR 41BBz (CD19...

Memphis, TNPHASE160 participantsSt. Jude Children's Research Hospital

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NCT07012044Recruiting

A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

This phase I trial tests the safety, side effects, and best dose of ASTX727 and filgrastim for the treatment of children with high risk acute myeloid leukemia that has come back after a period of impr...

Memphis, TNPHASE147 participantsNational Cancer Institute (NCI)

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NCT05101551Recruiting

Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

This is a Phase 1, open label, multicenter, dose finding study with dose expansion intended to evaluate the safety and tolerability of talazoparib in combination with conventional chemotherapy. Prelim...

Memphis, TNPHASE134 participantsNorman J. Lacayo

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NCT06777979Recruiting

CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic Leukemia

This study is a phase I study designed to evaluate the safety of CD19-CD22-CAR T cells. Primary Objective: To determine the safety profile and propose the recommended phase 2 dose (RP2D) of autologo...

Memphis, TNPHASE130 participantsSt. Jude Children's Research Hospital

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NCT06810583Recruiting

A Prospective Trial of Dalbavancin-Based Prophylaxis in Children and Adolescents With High-Risk Leukemia

This is a single-arm pilot clinical trial evaluating dalbavancin-based prophylaxis in children and adolescents with acute myeloid leukemia or relapsed lymphoblastic leukemia receiving myelosuppressive...

Memphis, TNPHASE129 participantsSt. Jude Children's Research Hospital

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NCT06847269Recruiting

CAR T CELL Therapy for Pediatric, Adolescent and Young Adult Patients With CD19-Positive Leukemia

CAR19PK is a research study evaluating the use of lymphodepleting chemotherapy and chimeric antigen receptor (CAR) T cell therapy, a type of cellular therapy, for the treatment of refractory and/or re...

Memphis, TNPHASE225 participantsSt. Jude Children's Research Hospital

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NCT06177067Recruiting

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

This is a research study to find out if adding a new study drug called revumenib to commonly used chemotherapy drugs is safe and if they have beneficial effects in treating patients with acute myeloid...

Memphis, TNPHASE124 participantsSt. Jude Children's Research Hospital

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NCT07228741Recruiting

Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity

This is a 28-week, single-arm, open-label phase II clinical trial evaluating the combination of Tirzepatide and remote, supervised, tailored resistance exercise training to achieve weight loss in adul...

Memphis, TNPHASE220 participantsSt. Jude Children's Research Hospital

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NCT06376162Recruiting

Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

The primary objective of the study is to determine the recommended phase 2 dose (RP2D) of ziftomenib in combination with chemotherapy (FLA) in children with relapsed or refractory KMT2A-r, NUP98-r, or...

Memphis, TNPHASE120 participantsPedAL BCU, LLC

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About Leukemia Clinical Trials in Memphis

Leukemia is a group of blood cancers that develop in the bone marrow and result in abnormal white blood cells. Types include acute myeloid (AML), acute lymphoblastic (ALL), chronic myeloid (CML), and chronic lymphocytic (CLL). Treatment varies by type and may include chemotherapy, targeted therapy, and stem cell transplant.

There are currently 23 leukemia clinical trials recruiting participants in Memphis, TN. These studies are seeking a combined 12,864 participants. Research is being sponsored by St. Jude Children's Research Hospital, H. Lee Moffitt Cancer Center and Research Institute, Merck Sharp & Dohme LLC and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Leukemia Clinical Trials in Memphis — FAQ

Are there leukemia clinical trials in Memphis?

Yes, there are 23 leukemia clinical trials currently recruiting in Memphis, TN. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Memphis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Memphis research site will contact you about next steps.

Are clinical trials in Memphis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Memphis studies also compensate for your time and travel.

What leukemia treatments are being tested?

The 23 active trials in Memphis are testing new therapies including novel drugs, biologics, and treatment approaches for leukemia.

Data updated July 18, 2026 from ClinicalTrials.gov