Miami, FL10 Active Studies

Head and Neck Cancer Clinical Trials in Miami, FL

Find 10 actively recruiting head and neck cancer clinical trials in Miami, FL. Connect with local research sites and explore new treatment options.

10
Active Trials
10
Sponsors
2,487
Enrolling

Recruiting Head and Neck Cancer Studies in Miami

RecruitingMiami, FLNCT05451004

SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer

This study is being done to answer the following question: Is the chance of cancer spreading or returning the same if radiotherapy to the neck is guided, by using a special imaging study called lymph...

510 participants
Canadian Cancer Trials Group
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RecruitingMiami, FLNCT06699212

A Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab in First-line Treatment of Locoregional Recurrent Squamous Cell Carcinoma of the Head and Neck With No Distant Metastases

The goal of this clinical trial is to learn if ASP-1929 photoimmunotherapy (PIT) in combination with pembrolizumab works to treat recurrent squamous cell cancer of the head and neck (HNSCC) with no di...

412 participants
Rakuten Medical, Inc.
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RecruitingMiami, FLNCT06295731

INBRX-106 in Combination With Pembrolizumab in First-line PD-L1 CPS≥20 HNSCC

This seamless phase 2/3 randomized controlled study will evaluate the efficacy and safety of the hexavalent OX40 agonist antibody INBRX-106 combined with the anti-PD-1 antibody pembrolizumab versus pe...

410 participants
Inhibrx Biosciences, Inc
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RecruitingMiami, FLNCT04534205

A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1

An open-label, controlled, multi-site, interventional, 2-arm, Phase II/III trial of BNT113 in combination with pembrolizumab vs pembrolizumab monotherapy as first line treatment in patients with unres...

350 participants
BioNTech SE
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RecruitingMiami, FLNCT06563479

A Study Comparing Personalized Radiation Therapy With Standard Radiation Therapy in People With HPV-Positive Throat Cancer

The researchers are doing this study to find out if a personalized approach to chemoradiation therapy (which may include a lower dose of radiation) is as effective as the standard chemoradiation thera...

291 participants
Memorial Sloan Kettering Cancer Center
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RecruitingMiami, FLNCT05966194

RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer

The purpose of this study is to determine if RRx-001, which is added on to the cisplatin and radiation treatment, reduces the incidence of severe oral mucositis in patients with head and neck cancers....

216 participants
EpicentRx, Inc.
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RecruitingMiami, FLNCT05962242

HPV DNA-Guided Radiotherapy De-intensification of Head and Neck Squamous Cell Carcinoma

The study will evaluate the safety and effectiveness of a lower than standard dose of radiation for definitive or adjuvant treatment of head and neck squamous cell carcinomas....

90 participants
University of Virginia
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RecruitingMiami, FLNCT04291105

Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients

This is a Phase 2 study designed to determine the preliminary anti-tumor activity and confirm the safety of VV1 in combination with cemiplimab. The study will enroll patients with three distinct separ...

87 participants
Vyriad, Inc.
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RecruitingMiami, FLNCT05814666

Activity and Safety of Danvatirsen and Pembrolizumab in HNSCC

Open-label, Phase II, randomized, controlled study evaluating the efficacy and safety of danvatirsen in combination with pembrolizumab compared with pembrolizumab alone as first-line treatment of pati...

81 participants
Flamingo Therapeutics NV
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RecruitingMiami, FLNCT05893888

Safety and Efficacy Study of PRV111 and PRV211 in Subjects With Oral Squamous Cell Carcinoma

Arm 1 ( Phase 2/3 Run in ): PRV111: Topical Locoregional Delivery Placed Over the Tumor Region Primary Endpoint: Overall Response Rate (ORR) Primary Objective: Demonstrate the safety and efficacy of ...

40 participants
Privo Technologies
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About Head and Neck Cancer Clinical Trials in Miami

Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.

There are currently 10 head and neck cancer clinical trials recruiting participants in Miami, FL. These studies are seeking a combined 2,487 participants. Research is being sponsored by Canadian Cancer Trials Group, Rakuten Medical, Inc., Inhibrx Biosciences, Inc and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Head and Neck Cancer Clinical Trials in Miami — FAQ

Are there head and neck cancer clinical trials in Miami?

Yes, there are 10 head and neck cancer clinical trials currently recruiting in Miami, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Miami?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Miami research site will contact you about next steps.

Are clinical trials in Miami free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Miami studies also compensate for your time and travel.

What head and neck cancer treatments are being tested?

The 10 active trials in Miami are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.

Data updated March 2, 2026 from ClinicalTrials.gov