24 Lung Cancer Clinical Trials in Middletown, CT (2026)

Q: How do I join a clinical trial in Middletown?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Middletown research site will contact you.

Recruiting Lung Cancer Studies in Middletown

NCT06424327Recruiting

A Registry for People With Lung Cancer

Participants will complete questionnaires before surgery, between 2 to 4 weeks after surgery, and 6 months after surgery....

Middletown, CT600 participantsMemorial Sloan Kettering Cancer Center

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NCT04410796Recruiting

Osimertinib Alone or With Chemotherapy for EGFR-Mutant Lung Cancers

This study will compare the effectiveness of osimertinib alone with the combination of osimertinib and chemotherapy (carboplatin and pemetrexed) in people with metastatic lung cancer that has a change...

Middletown, CT571 participantsMemorial Sloan Kettering Cancer Center

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NCT06717334Recruiting

A Study of Lung Cancer Screening in People With Unexplained Weight Loss

The researchers are doing this study to see if people with unexplained weight loss who have lung cancer screening are more likely to have or develop lung cancer than people without unexplained weight ...

Middletown, CT409 participantsMemorial Sloan Kettering Cancer Center

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NCT05967689Recruiting

A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.

The purpose of this study is to evaluate the safety, efficacy and pharmacokinetics (PK) of zipalertinib in participants with locally advanced or metastatic Non-Small Cell Lung Cancer (NSCLC) harboring...

Middletown, CT220 participantsTaiho Oncology, Inc.

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NCT06033248Recruiting

Using Urine Samples to Identify Lung Cancer

The researchers are doing this study to test the ability of an animal biosensor platform (ABP) to detect NSCLC. Participants in this study will either be diagnosed with NSCLC, suspected to have NSCLC,...

Middletown, CT210 participantsMemorial Sloan Kettering Cancer Center

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NCT05424029Recruiting

Extracellular Vesicles and Particles (EVP) as Biomarkers of Recurrence in Non-Small Cell Lung Cancer

The purpose of this study is to find out if fluid rinsed from peoples' airways (bronchial washing samples) during routine surgery to remove (resect) their non-small cell lung cancer (NSCLC) tumors con...

Middletown, CT200 participantsMemorial Sloan Kettering Cancer Center

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NCT07690917Recruiting

A Study of a New PET Scanner in People With Cancer

The researchers are doing this study to test the capabilities of a new total-body PET scanner called the Biograph Vision Quadra. The researchers want to learn whether this scanner can produce better P...

Middletown, CT90 participantsMemorial Sloan Kettering Cancer Center

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NCT01639508Recruiting

Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity

The purpose of this phase II study is to find out what effects cabozantinib (XL184) has, good and/or bad, in patients whose tumors one of the following gene changes RET, ROS1, or NTRK fusion, or incre...

Middletown, CT86 participantsMemorial Sloan Kettering Cancer Center

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NCT06957314Recruiting

A Study of Hospital-at-Home for People Receiving Tarlatamab

The purpose of this study is to find out whether a Hospital-at-Home (HaH) program is a more efficient way to monitor people's health after receiving tarlatamab than monitoring in the hospital (inpatie...

Middletown, CT70 participantsMemorial Sloan Kettering Cancer Center

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NCT05657873Recruiting

A Study of Targeted Radiation Therapy in People With Non-Small Cell Lung Cancer (NSCLC)

The purpose of this study is to see whether adding liver stereotactic ablative radiotherapy/L-SABR to standard drug therapy is better than standard drug therapy alone for people with metastatic non-sm...

Middletown, CT68 participantsMemorial Sloan Kettering Cancer Center

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NCT07535437Recruiting

A Study of Ivonescimab in Combination With Dato-DXd or Osimertinib in People With Non-Small Cell Lung Cancer

The researchers are doing this study to find out whether ivonescimab in combination with datopotamab deruxtecan- (Dato-DXd) or osimertinib are safe and effective treatments in people with non-small ce...

Middletown, CT66 participantsMemorial Sloan Kettering Cancer Center

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NCT04991025Recruiting

Adding Certolizumab to Chemotherapy + Nivolumab in People Who Have Lung Cancer That Can Be Treated With Surgery

The purpose of the study is to explore adding the study drug certolizumab to standard chemotherapy as it may reduce the inflammation caused by the cancer and make the chemotherapy more effective in sh...

Middletown, CT60 participantsMemorial Sloan Kettering Cancer Center

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NCT07218601Recruiting

Using E-Nose Technology to Track Treatment Response in People With Non-Small Cell Lung Cancer

The researchers are doing this study to test the ability of a new technology called breathprinting, or electronic nose (E-Nose), to measure changes in certain chemicals in the breath before and after ...

Middletown, CT60 participantsMemorial Sloan Kettering Cancer Center

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NCT06741085Recruiting

A Study of Stereotactic Radiosurgery (SRS) and Standard Treatment in People With Lung Cancer That Has Spread to the Brain

The researchers are doing this study is to find out whether treating brain metastasis with SRS after 3 months of therapy with osimertinib is better than treating with osimertinib alone in people with ...

Middletown, CT56 participantsMemorial Sloan Kettering Cancer Center

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NCT06007937Recruiting

A Study of Lorlatinib in Combination With Ramucirumab in People With Lung Cancer

This study will test the safety of the combination of ramucirumab and lorlatinib. The researchers will test one or two different doses of lorlatinib in combination with ramucirumab to find the drug co...

Middletown, CT56 participantsMemorial Sloan Kettering Cancer Center

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NCT07535463Recruiting

A Study of Ivonescimab, Chemotherapy, and Stereotactic Radiosurgery for People With Non-Small Cell Lung Cancer

The researchers are doing this study to test the safety of ivonescimab given in combination with standard chemotherapy and stereotactic radiosurgery (SRS) in people with non-small cell lung cancer (NS...

Middletown, CT53 participantsMemorial Sloan Kettering Cancer Center

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NCT06582771Recruiting

A Study of Sotorasib in People with Non-Small Cell Lung Cancer

The researchers are doing this study to see if sotorasib is a safe and effective treatment for people with advanced non-small cell lung cancer (NSCLC) with a KRAS G12C mutation who have not received t...

Middletown, CT39 participantsMemorial Sloan Kettering Cancer Center

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NCT07594522Recruiting

A Study of Ivonescimab in People With Non-Small Cell Lung Cancer

The researchers are doing this study to find out whether ivonescimab after receiving standard stereotactic body radiotherapy (SBRT) is an effective treatment in people with Non-Small Cell Lung Cancer ...

Middletown, CT36 participantsMemorial Sloan Kettering Cancer Center

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NCT07323732Recruiting

A Study of BIO 300 and Thoracic Radiation Therapy in People With Non-Small Cell Lung Cancer and Interstitial Lung Disease

The purpose of this study to find out whether giving BIO 300 in combination with thoracic radiation therapy is effective in preventing pneumonitis in people with non-small cell lung cancer (NSCLC) and...

Middletown, CT25 participantsMemorial Sloan Kettering Cancer Center

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NCT06807632Recruiting

A Study of Valemetostat in Combination With Atezolizumab in People With Lung Cancer

This study will test whether valemetostat in combination with atezolizumab is a safe treatment that causes few or mild side effects in people with extensive-stage small cell lung cancer (SCLC). The re...

Middletown, CT24 participantsMemorial Sloan Kettering Cancer Center

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NCT07619339Recruiting

A Study of Tepotinib and Ivonescimab in People With Non-Small Cell Lung Cancer

The researchers are doing this study to find out whether the combination of tepotinib and ivonescimab is a safe and effective treatment for people with non-small cell lung cancer (NSCLC) that is posit...

Middletown, CT16 participantsMemorial Sloan Kettering Cancer Center

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NCT07428044Recruiting

A Study of Trastuzumab Deruxtecan in People With Non-Small Cell Lung Cancer

The purpose of this study is to find out how many people with HER2-amplified or HER2-mutated non-small cell lung cancer (NSCLC) experience a decrease in tumor viability when they receive trastuzumab d...

Middletown, CT14 participantsMemorial Sloan Kettering Cancer Center

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NCT05607108Recruiting

A Study of ZEN003694 in People With Squamous Cell Lung Cancer

The purpose of this study is to find out whether ZEN003694 is an effective treatment for people with advanced squamous cell lung cancer with a mutation in the NSD3 gene. ZEN003694 is a type of drug c...

Middletown, CT13 participantsMemorial Sloan Kettering Cancer Center

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NCT06863233Recruiting

A Study of CD8+ T Cell Imaging During Treatment in People With Non-Small Cell Lung Cancer

The purpose of this study to learn whether PET/CT (positron emission tomography/computed tomography) scans using an imaging agent (radiotracer) called zirconium Zr 89 crefmirlimab berdoxam is a safe a...

Middletown, CT5 participantsMemorial Sloan Kettering Cancer Center

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About Lung Cancer Clinical Trials in Middletown

Lung cancer is the leading cause of cancer death worldwide, starting in the cells of the lungs. The two main types are non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Treatments include surgery, chemotherapy, radiation, immunotherapy, and targeted drugs.

There are currently 24 lung cancer clinical trials recruiting participants in Middletown, CT. These studies are seeking a combined 3,047 participants. Research is being sponsored by Memorial Sloan Kettering Cancer Center, Taiho Oncology, Inc.. Clinical trial participation is free and participants receive study-related medical care at no cost.

Lung Cancer Clinical Trials in Middletown — FAQ

Are there lung cancer clinical trials in Middletown?

Yes, there are 24 lung cancer clinical trials currently recruiting in Middletown, CT. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Middletown?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Middletown research site will contact you about next steps.

Are clinical trials in Middletown free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Middletown studies also compensate for your time and travel.

What lung cancer treatments are being tested?

The 24 active trials in Middletown are testing new therapies including novel drugs, biologics, and treatment approaches for lung cancer.

Data updated July 13, 2026 from ClinicalTrials.gov