31 Breast Cancer Clinical Trials in Middletown, CT (2026)

Q: How do I join a clinical trial in Middletown?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Middletown research site will contact you.

Recruiting Breast Cancer Studies in Middletown

NCT07308717Recruiting

Gabapentin And Breast Surgery Decision Architecture Randomization Trial (GABS-DART) Protocol

This study aims to assess whether gabapentin should be a standard component of peri-operative pain control in mastectomy patients at Memorial Sloan Kettering Cancer Center....

Middletown, CT1,896 participantsMemorial Sloan Kettering Cancer Center

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NCT06954337Recruiting

MATCH-UP: MAking Telehealth-Delivery of Cancer Care at Home Effective and Safe-Upscaled: A Pragmatic Cluster Randomized Trial

Many people with cancer spend a lot of time and money traveling to and from the doctor's office for cancer care. MSK's goal is to make getting cancer care easier by cutting down the need to make in-pe...

Middletown, CT1,750 participantsMemorial Sloan Kettering Cancer Center

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NCT02743858Recruiting

Lymphedema Surveillance Study

This study is being done to find out how many women develop lymphedema after an axillary lymph node dissection. The investigators also want to look for reasons why some women get lymphedema and others...

Middletown, CT1,250 participantsMemorial Sloan Kettering Cancer Center

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NCT07294703Recruiting

Factors Associated With Breast Cancer Risks and Outcomes

The purpose of this study is to learn more about risks and outcomes of breast cancer in people with different backgrounds. Tissue and blood will be collected from participants for research purposes. P...

Middletown, CT750 participantsMemorial Sloan Kettering Cancer Center

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NCT06721065Recruiting

A Study of Language Interpretation Solutions for People With Breast Cancer

The study will be conducted in 2 overlapping phases. In Phase 1, there will be a 3-arm randomized controlled trial of Remote Simultaneous Medical Interpreting/RSMI (Arm 1), versus Remote Consecutive M...

Middletown, CT700 participantsMemorial Sloan Kettering Cancer Center

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NCT00823654Recruiting

Serum Biomarkers to Characterize the Effects of Therapy on Ovarian Reserve in Premenopausal Women With Early-stage Breast Cancer or BRCA Mutations

The purpose of this study is to learn more about the effects of your BRCA mutation on the ovaries. The BRCA gene can make it hard to conceive a child in the future. It may also bring on early menopaus...

Middletown, CT609 participantsMemorial Sloan Kettering Cancer Center

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NCT03572374Recruiting

Talking to Employers and Medical Staff About Breast Cancer Treatment and Your Job

The purpose of this study is learn more about how being treated for breast cancer affects patients' employment. Researchers are testing an early version of a mobile app designed to help breast cancer ...

Middletown, CT546 participantsMemorial Sloan Kettering Cancer Center

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NCT01788839Recruiting

Longitudinal Sexual and Reproductive Health Study of Women With Breast Cancer and Lymphoma

The purpose of this study is to see how cancer treatment affects sexual and reproductive function. The patient will also be asked to participate in blood draws to see if and how cancer treatment affec...

Middletown, CT475 participantsMemorial Sloan Kettering Cancer Center

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NCT06334354Recruiting

A Study of Changes in Thinking Related to Aging and Cancer in Breast Cancer Survivors (TRAC)

The purpose of this study is to look at how differences in cognitive (mental) function develop over time in breast cancer survivors compared to volunteers without a history of cancer (healthy voluntee...

Middletown, CT420 participantsMemorial Sloan Kettering Cancer Center

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NCT07220967Recruiting

A Study of Antibiotic Delivery to Prevent Infection After Breast Tissue Expander Placement

The researchers are doing this study to find out whether Stimulan Rapid Cure works to reduce the risk of infections in people getting tissue expanders placed during mastectomy. The researchers will al...

Middletown, CT392 participantsMemorial Sloan Kettering Cancer Center

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NCT06144164Recruiting

A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer

The purpose of this study to test whether a comprehensive program may help the lymph fluid to drain out of the arm and prevent lymphedema in participants with breast cancer....

Middletown, CT285 participantsMemorial Sloan Kettering Cancer Center

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NCT04084730Recruiting

Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer

The purpose of this study is to determine if the dose of radiation therapy that is effective in producing a treatment response, delivered over a shorter treatment period, is a safe approach that cause...

Middletown, CT280 participantsMemorial Sloan Kettering Cancer Center

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NCT06099769Recruiting

A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer

The researchers are doing this study to find out if the study drug, enzalutamide, alone or combined with the study drug, mifepristone, is effective in treating advanced or metastatic androgen receptor...

Middletown, CT201 participantsMemorial Sloan Kettering Cancer Center

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NCT07053085Recruiting

A Study of Surgery and Radiotherapy in People With Breast Cancer

The researchers are doing this study to see if the combination of surgery, locoregional radiation therapy, SBRT (stereotactic body radiation therapy), and the usual approach is more effective in treat...

Middletown, CT178 participantsMemorial Sloan Kettering Cancer Center

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NCT07483307Recruiting

A Study of the Impact of Endocrine Therapy on Surgical Outcomes in People With Lobular Breast Cancer

The purpose of this study is to look at how effective neoadjuvant (before surgery) endocrine therapy (NET) is in participants with invasive lobular carcinoma (ILC) who have breast-conserving surgery (...

Middletown, CT176 participantsMemorial Sloan Kettering Cancer Center

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NCT03351348Recruiting

Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control

The purpose of this study is to compare using FDA-approved bupivacaine (a numbing medicine), along with the usual medications for post-operative pain control to using the usual medications for postope...

Middletown, CT165 participantsMemorial Sloan Kettering Cancer Center

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NCT05716893Recruiting

Study of Aerobic Training for People Receiving Chemotherapy for Breast Cancer

In this study, investigators will compare standard Aerobic Training/AT with adaptive Aerobic Training/AT. Standard AT will be a fixed (unchanging) amount of walking each week, while adaptive AT will a...

Middletown, CT140 participantsMemorial Sloan Kettering Cancer Center

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NCT07335354Recruiting

A Study of a Decision Tool for People Considering Breast Reconstruction Surgery

The purpose of this study is to find out whether it is practical (feasible) to do a larger study looking at the effectiveness of the Breast Reconstruction Decision Aid Tool (RECONJOINT) for breast rec...

Middletown, CT131 participantsMemorial Sloan Kettering Cancer Center

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NCT05590949Recruiting

Observational Study of Bone Complications in People With Post-menopausal Breast Cancer Who Have Stopped Treatment With Denosumab and Aromatase Inhibitors

The purpose of this study to gather information about changes in the bones after stopping treatment with aromatase inhibitor/AI and denosumab. The study team will collect information from 5 standard c...

Middletown, CT100 participantsMemorial Sloan Kettering Cancer Center

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NCT07459673Recruiting

HERizon-Breast: A ctDNA-Guided Adaptive Study of Sequential Anti-HER2 Therapies and CNS Prophylaxis to Induce Long-Term Remission

Thie purpose of this study is to find out whether a personalized treatment approach-using a series of ctDNA tests along with standard imaging scans to help decide when to step up (escalate) or decreas...

Middletown, CT60 participantsMemorial Sloan Kettering Cancer Center

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NCT05412225Recruiting

A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer

The purpose of this study to test an alternative treatment approach that involves giving participants radiotherapy before their mastectomy (preoperative radiotherapy) and performing immediate reconstr...

Middletown, CT60 participantsMemorial Sloan Kettering Cancer Center

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NCT07042581Recruiting

A Study of Revaree Plus in People With Breast Cancer

The purpose of this study is to find out whether Revaree Plus is effective at improving vaginal health for people who are having symptoms of vaginal dryness during breast cancer treatment....

Middletown, CT60 participantsMemorial Sloan Kettering Cancer Center

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NCT06110793Recruiting

A Study of Lenvatinib, Pembrolizumab, and Fulvestrant in People With Breast Cancer

The purpose of this study is to test whether the combination of lenvatinib, pembrolizumab, and fulvestrant is a safe and effective treatment that causes few or mild side effects in people with ER+/HER...

Middletown, CT56 participantsMemorial Sloan Kettering Cancer Center

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NCT05570253Recruiting

A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer

The researchers are doing this study to find out whether the study drug, SDX-7320, when combined with the standard chemotherapy eribulin, is an effective treatment for people with TNBC and metabolic d...

Middletown, CT55 participantsMemorial Sloan Kettering Cancer Center

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NCT05534438Recruiting

A Study on Adding Precisely Targeted Radiation Therapy (Stereotactic Body Radiation Therapy) to the Usual Treatment Approach (Drug Therapy) in People With Breast Cancer

The purpose of this study is to see if using Stereotactic Body Radiation Therapy/SBRT to treat a single metastatic site where cancer has worsened may be an effective treatment for people with oligomet...

Middletown, CT46 participantsMemorial Sloan Kettering Cancer Center

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NCT04683679Recruiting

A Study of Radiation Therapy With Pembrolizumab and Olaparib or Other Radiosensitizers in Women Who Have Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancer

The purpose of this study is to find out whether adding pembrolizumab, with or without olaparib, to standard radiation therapy is a safe and effective treatment for metastatic breast cancer, , and to ...

Middletown, CT34 participantsMemorial Sloan Kettering Cancer Center

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NCT06557148Recruiting

A Study Comparing Cancer Imaging Approaches in People With Lobular Breast Cancer

The purpose of this study to compare two types of cancer imaging scans to see which is better at detecting and monitoring metastatic ILC. This study will compare PET/CT (positron emission tomography/c...

Middletown, CT30 participantsMemorial Sloan Kettering Cancer Center

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NCT06246968Recruiting

A Study of Pembrolizumab and Cryoablation in People With Breast Cancer

Participants will have a confirmed diagnosis of metastatic breast cancer and will receive pembrolizumab in combination with cryoablation OR pembrolizumab alone. Participants will be randomly assigned....

Middletown, CT30 participantsMemorial Sloan Kettering Cancer Center

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NCT06678269Recruiting

A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer

The purpose of this study is to test different doses of abemaciclib to find the best dose in participants while receiving hormone therapy and radiation therapy....

Middletown, CT28 participantsMemorial Sloan Kettering Cancer Center

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NCT05837767Recruiting

A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue

The purpose of this study is to find out whether lattice radiation therapy (LRT) is an effective radiation therapy technique when compared to standard stereotactic body radiation therapy (SBRT). The s...

Middletown, CT26 participantsMemorial Sloan Kettering Cancer Center

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NCT07218250Recruiting

A Study of a One-Time Counseling Session to Help Reduce Depression, Anxiety, and Distress in People With Breast Cancer

The purpose of this study is to see if a Single Counseling Session for Cancer can help reduce psychosocial distress and improve quality of life in people with breast cancer who are waiting to receive ...

Middletown, CT26 participantsMemorial Sloan Kettering Cancer Center

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About Breast Cancer Clinical Trials in Middletown

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 31 breast cancer clinical trials recruiting participants in Middletown, CT. These studies are seeking a combined 10,955 participants. Research is being sponsored by Memorial Sloan Kettering Cancer Center. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in Middletown — FAQ

Are there breast cancer clinical trials in Middletown?

Yes, there are 31 breast cancer clinical trials currently recruiting in Middletown, CT. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Middletown?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Middletown research site will contact you about next steps.

Are clinical trials in Middletown free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Middletown studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 31 active trials in Middletown are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated July 13, 2026 from ClinicalTrials.gov