6 Atrial Fibrillation Clinical Trials in Naples, FL (2026)

Q: How do I join a clinical trial in Naples?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Naples research site will contact you.

Recruiting Atrial Fibrillation Studies in Naples

NCT06436924Recruiting

Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day

SAFE HV is an observational, prospective, multi-center, non-randomized study evaluating real-world clinical experience of centers where a single procedural physician schedules eight or more left atria...

Naples, FL678 participantsHeart Rhythm Clinical and Research Solutions, LLC

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NCT07298473Recruiting

Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)

Conquer-AF is a prospective, multi-center, interventional, non-randomized clinical study that will enroll up to 400 subjects at up to 30 sites across the United States, Europe, and Australia. Subject...

Naples, FLNA400 participantsMedtronic Cardiac Ablation Solutions

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NCT06735534Recruiting

Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System

The ReMATCH Study is a prospective, single arm, open label, multi-center, study utilizing the FARAPULSE PFA System, including the FARAWAVE and FARAPOINT PFA Catheters....

Naples, FLNA376 participantsBoston Scientific Corporation

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NCT07308847Recruiting

Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With the Sphere-360™ Catheter and Affera™ Mapping and Ablation System (Horizon 360)

The study is a prospective, single-arm, pre-market clinical study and will enroll up to 300 subjects at up to 26 sites in the United States (US) for analysis of primary objectives. No single site may ...

Naples, FLNA300 participantsMedtronic Cardiac Ablation Solutions

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NCT06324201Recruiting

The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.

Observational, multi-center, non-randomized, post-market study. This is a nested sub-study of the REAL AF Registry. Consecutive symptomatic drug refractory paroxysmal atrial fibrillation (PAF) patient...

Naples, FL250 participantsHeart Rhythm Clinical and Research Solutions, LLC

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NCT06529978Recruiting

Endocardial Mapping With the CoreMap EP Mapping System

This is a global, multi-site, prospective, feasibility study....

Naples, FLNA245 participantsCoreMap Inc.

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About Atrial Fibrillation Clinical Trials in Naples

Atrial fibrillation (AFib) is the most common type of heart arrhythmia, causing an irregular and often rapid heartbeat. It significantly increases the risk of stroke, heart failure, and other complications. Treatment includes blood thinners, heart rate or rhythm control medications, and procedures like ablation.

There are currently 6 atrial fibrillation clinical trials recruiting participants in Naples, FL. These studies are seeking a combined 2,249 participants. Research is being sponsored by Heart Rhythm Clinical and Research Solutions, LLC, Medtronic Cardiac Ablation Solutions, Boston Scientific Corporation and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Atrial Fibrillation Clinical Trials in Naples — FAQ

Are there atrial fibrillation clinical trials in Naples?

Yes, there are 6 atrial fibrillation clinical trials currently recruiting in Naples, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Naples?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Naples research site will contact you about next steps.

Are clinical trials in Naples free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Naples studies also compensate for your time and travel.

What atrial fibrillation treatments are being tested?

The 6 active trials in Naples are testing new therapies including novel drugs, biologics, and treatment approaches for atrial fibrillation.

Data updated July 19, 2026 from ClinicalTrials.gov