100 Active Studies

Atrial Fibrillation Clinical Trials Near You

Also searched as: AFib, irregular heartbeat, arrhythmia, AF clinical trials

Find 100 actively recruiting atrial fibrillation research studies near you. Connect with study sites, check eligibility, and explore new treatment options.

100Active Trials
173+Locations
157,308Participants Needed

Recruiting Studies

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Data: ClinicalTrials.gov · Source of record for eligibility and locations

Top Cities for Atrial Fibrillation Clinical Trials

Atrial Fibrillation clinical trials are recruiting across 173 cities. Here are the cities with the most active studies:

Atrial Fibrillation Trial Phases

NA(42 studies)
PHASE4(6 studies)
PHASE3(6 studies)
PHASE2(6 studies)
PHASE1(2 studies)
EARLY_PHASE1(1 study)

72 research organizations are sponsoring atrial fibrillation trials.

About Atrial Fibrillation

Atrial fibrillation (AFib) is the most common type of heart arrhythmia, causing an irregular and often rapid heartbeat. It significantly increases the risk of stroke, heart failure, and other complications. Treatment includes blood thinners, heart rate or rhythm control medications, and procedures like ablation.

Clinical trials are advancing new treatments for atrial fibrillation. Currently, 100 studies are recruiting a combined 157,308 participants across the United States. Research is being conducted by 72 organizations including Heart Rhythm Clinical and Research Solutions, LLC, Medtronic, American Heart Association and 69 others.

2026 Atrial Fibrillation Research Landscape

As of July 2026, the atrial fibrillation clinical trial landscape includes 100 actively recruiting studies across 173 cities in the United States. These studies are collectively seeking 157,308 participants, with an average enrollment target of 1,573 per study.

The research spans multiple phases of development: 42 studies are in NA, 6 studies are in PHASE4, 6 studies are in PHASE3, 6 studies are in PHASE2, 2 studies are in PHASE1, 1 study is in EARLY_PHASE1. The presence of Phase 3 trials indicates that some atrial fibrillation treatments are in late-stage testing and may be approaching regulatory review.

Research is being led by 72 different organizations, including Heart Rhythm Clinical and Research Solutions, LLC, Medtronic, American Heart Association, VA Office of Research and Development, AtriCure, Inc., and 67 others. The large number of sponsors reflects significant research interest and investment in atrial fibrillation treatment advancement.

Geographically, atrial fibrillation trials are most concentrated in Jonesboro, Arkansas (17 trials); Boston, Massachusetts (17 trials); New York, New York (15 trials); Birmingham, Alabama (13 trials); Los Angeles, California (11 trials) and 7 other cities.

Featured Atrial Fibrillation Studies

Highlighted recruiting studies for atrial fibrillation, selected by enrollment size and research scope.

RecruitingNCT04088071

Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias

The primary purpose of this Registry is to assess procedural safety and long-term effectiveness of catheter ablations in the treatment of subjects with PAF, PsAF, and VA. The Registry will utilize real world clinical data obtained from the use of commercially available CARTO™ technologies under the authority of a health care practitioner within a legitimate practitioner-subject relationship. Data ...

Sponsor: Heart Rhythm Clinical and Research Solutions, LLC· 20,000 participants· 10 locations (Birmingham, Mobile, Chandler, Tucson)
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RecruitingNCT00271180

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

The main purpose of the Product Performance Report (formerly referred to as System Longevity Study) is to evaluate long-term performance of Medtronic market-released cardiac rhythm products by analyzing product survival probabilities.

Sponsor: Medtronic· 20,000 participants· 10 locations (Birmingham, Anchorage, Chandler, Jonesboro)
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RecruitingNCT06245187

Get With the Guidelines Atrial Fibrillation Registry

Get With The Guidelines-Atrial Fibrillation is designed to assist hospital care teams in consistently providing the latest evidence-based treatment for their AFib patients. At the same time, it offers a means of monitoring the quality of AFib care in U.S. hospitals and building a database for continued research and further quality improvement.

Sponsor: American Heart Association· 17,198 participants· 1 location (Dallas)
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Frequently Asked Questions About Atrial Fibrillation Clinical Trials

Are there atrial fibrillation clinical trials near me?

Yes, there are 100 atrial fibrillation clinical trials currently recruiting across 173+ cities in the United States, including Jonesboro, Arkansas; Boston, Massachusetts; New York, New York. Browse the studies above to find one at a location convenient for you.

How do I join a atrial fibrillation clinical trial?

To join a atrial fibrillation clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.

Are atrial fibrillation clinical trials free?

Yes, participation in atrial fibrillation clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.

What types of atrial fibrillation treatments are being studied?

Current atrial fibrillation clinical trials are testing a range of approaches across NA (42 studies), PHASE4 (6 studies), PHASE3 (6 studies), PHASE2 (6 studies), PHASE1 (2 studies), EARLY_PHASE1 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 72 research organizations.

Is it safe to participate in atrial fibrillation clinical trials?

Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.

Data updated July 17, 2026 from ClinicalTrials.gov

About This Data

Data: ClinicalTrials.gov · Source of record for eligibility and locations

Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.

Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.

Page reviewed by the HelloStudys Research Team · Last updated July 17, 2026 · Data from ClinicalTrials.gov