Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Peripheral Artery Disease Clinical Trials
Peripheral Artery Disease clinical trials are recruiting across 114 cities. Here are the cities with the most active studies:
Peripheral Artery Disease Trial Phases
45 research organizations are sponsoring peripheral artery disease trials.
About Peripheral Artery Disease
Peripheral artery disease (PAD) is a circulatory condition where narrowed arteries reduce blood flow to the limbs, especially the legs. Common symptoms include leg pain when walking (claudication). Treatment includes lifestyle changes, medications, and sometimes procedures to improve blood flow.
Clinical trials are advancing new treatments for peripheral artery disease. Currently, 66 studies are recruiting a combined 45,725 participants across the United States. Research is being conducted by 45 organizations including Baylor Research Institute, Regeneron Pharmaceuticals, Population Health Research Institute and 42 others.
2026 Peripheral Artery Disease Research Landscape
As of July 2026, the peripheral artery disease clinical trial landscape includes 66 actively recruiting studies across 114 cities in the United States. These studies are collectively seeking 45,725 participants, with an average enrollment target of 693 per study.
The research spans multiple phases of development: 39 studies are in NA, 8 studies are in PHASE3, 5 studies are in PHASE2, 4 studies are in PHASE4, 2 studies are in PHASE1, 1 study is in EARLY_PHASE1. The presence of Phase 3 trials indicates that some peripheral artery disease treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 45 different organizations, including Baylor Research Institute, Regeneron Pharmaceuticals, Population Health Research Institute, Boston Scientific Corporation, Eli Lilly and Company, and 40 others. The large number of sponsors reflects significant research interest and investment in peripheral artery disease treatment advancement.
Geographically, peripheral artery disease trials are most concentrated in Chicago, Illinois (10 trials); Omaha, Nebraska (7 trials); Minneapolis, Minnesota (6 trials); Boston, Massachusetts (5 trials); Detroit, Michigan (5 trials) and 7 other cities.
Featured Peripheral Artery Disease Studies
Highlighted recruiting studies for peripheral artery disease, selected by enrollment size and research scope.
Multi-Center Registry for Peripheral Arterial Disease Interventions and Outcomes
XLPAD is an observational study designed to evaluate the effectiveness and use of stent and non-stent based therapies among PAD patients. The study will create a registry that will include entry of procedural and clinical follow-up information into an online data collection software, REDCAP.Data available since Jan 1 2005 will be included in the registry, until 14,000 patients have been included. ...
Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease
This study is researching 2 different experimental drugs called REGN7508 and REGN9933. The study is focused on people who have Peripheral Artery Disease (PAD), which means that the blood vessels in their arms and legs have become too narrow. People with PAD have a higher risk of getting blood clots after procedures like Lower Extremity Revascularization (LER), a procedure to improve blood flow in ...
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk
The Low dose ColchicinE in pAtients with peripheral Artery DiseasE to address residual vascular Risk (LEADER-PAD) trial will evaluate if anti-inflammatory therapy with colchicine will reduce vascular events in patients with symptomatic peripheral artery disease.
Frequently Asked Questions About Peripheral Artery Disease Clinical Trials
Are there peripheral artery disease clinical trials near me?
Yes, there are 66 peripheral artery disease clinical trials currently recruiting across 114+ cities in the United States, including Chicago, Illinois; Omaha, Nebraska; Minneapolis, Minnesota. Browse the studies above to find one at a location convenient for you.
How do I join a peripheral artery disease clinical trial?
To join a peripheral artery disease clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are peripheral artery disease clinical trials free?
Yes, participation in peripheral artery disease clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of peripheral artery disease treatments are being studied?
Current peripheral artery disease clinical trials are testing a range of approaches across NA (39 studies), PHASE3 (8 studies), PHASE2 (5 studies), PHASE4 (4 studies), PHASE1 (2 studies), EARLY_PHASE1 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 45 research organizations.
Is it safe to participate in peripheral artery disease clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 16, 2026 · Data from ClinicalTrials.gov