Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Hypertension Clinical Trials
Hypertension clinical trials are recruiting across 154 cities. Here are the cities with the most active studies:
Hypertension Trial Phases
76 research organizations are sponsoring hypertension trials.
About Hypertension
Hypertension, or high blood pressure, is a common condition that increases the risk of heart disease, stroke, and kidney damage. Often called the "silent killer" because it usually has no symptoms. Management includes lifestyle modifications and medications to lower blood pressure.
Clinical trials are advancing new treatments for hypertension. Currently, 100 studies are recruiting a combined 136,240 participants across the United States. Research is being conducted by 76 organizations including OSF Healthcare System, Boston Medical Center, Alnylam Pharmaceuticals and 73 others.
2026 Hypertension Research Landscape
As of October 2026, the hypertension clinical trial landscape includes 100 actively recruiting studies across 154 cities in the United States. These studies are collectively seeking 136,240 participants, with an average enrollment target of 1,362 per study.
The research spans multiple phases of development: 47 studies are in NA, 12 studies are in PHASE3, 7 studies are in PHASE2, 3 studies are in PHASE4, 2 studies are in PHASE1. The presence of Phase 3 trials indicates that some hypertension treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 76 different organizations, including OSF Healthcare System, Boston Medical Center, Alnylam Pharmaceuticals, Rutgers, The State University of New Jersey, Mayo Clinic, and 71 others. The large number of sponsors reflects significant research interest and investment in hypertension treatment advancement.
Geographically, hypertension trials are most concentrated in Boston, Massachusetts (12 trials); Chicago, Illinois (12 trials); Los Angeles, California (10 trials); Birmingham, Alabama (7 trials); Phoenix, Arizona (7 trials) and 7 other cities.
Featured Hypertension Studies
Highlighted recruiting studies for hypertension, selected by enrollment size and research scope.
Examining Digital Health Care Delivery Models Through Medicaid Collaborative
The purpose of this study is to examine the intervention effectiveness and dissemination of digital health care delivery models for improving selected health outcomes in the Medicaid population.
Improving Hypertension Control in Safety-Net Settings: The Boston Hypertension Equity Alliance in Treatment
High blood pressure (BP) or hypertension (HTN) affects over 100 million individuals in the US, increasing the risk of adverse outcomes, including stroke, myocardial infarction (MI), and chronic kidney disease (CKD). Effective therapies include non-pharmacologic approaches and multiple medication classes. Successful HTN management requires ongoing patient engagement for BP monitoring and treatment ...
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
The purpose of this study is to evaluate whether zilebesiran versus placebo reduces the risk of cardiovascular (CV) death, nonfatal myocardial infarction (MI), nonfatal stroke, or heart failure (HF) events. This is an event-driven study that will continue until the targeted number of positively adjudicated primary endpoint clinical outcome events (COEs) have been reached.
Frequently Asked Questions About Hypertension Clinical Trials
Are there hypertension clinical trials near me?
Yes, there are 100 hypertension clinical trials currently recruiting across 154+ cities in the United States, including Boston, Massachusetts; Chicago, Illinois; Los Angeles, California. Browse the studies above to find one at a location convenient for you.
How do I join a hypertension clinical trial?
To join a hypertension clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are hypertension clinical trials free?
Yes, participation in hypertension clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of hypertension treatments are being studied?
Current hypertension clinical trials are testing a range of approaches across NA (47 studies), PHASE3 (12 studies), PHASE2 (7 studies), PHASE4 (3 studies), PHASE1 (2 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 76 research organizations.
Is it safe to participate in hypertension clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated October 19, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated October 19, 2026 · Data from ClinicalTrials.gov