6 Kidney Cancer Clinical Trials in Nashville, TX (2026)

Q: How do I join a clinical trial in Nashville?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Nashville research site will contact you.

Recruiting Kidney Cancer Studies in Nashville

NCT07049926Recruiting

Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

Substudy 03C is part of a larger research study that is testing experimental treatments for renal cell carcinoma (RCC). The larger study is the umbrella study (U03). The goal of substudy 03C is to ev...

Nashville, TX140 participantsMerck Sharp & Dohme LLC

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NCT07195682Recruiting

A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)

This is a first-in-human study of BMS-986506 in participants with advanced Clear Cell Renal Cell Carcinoma (ccRCC). The primary objective of this study is to find out if BMS-986506 is safe and can be ...

Nashville, TX125 participantsBristol-Myers Squibb

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NCT07188896Recruiting

A Randomized Trial of Fianlimab and Cemiplimab +/- Ipilimumab or Ipilimumab Plus Nivolumab in First-line Advanced Renal Cell Carcinoma (RCC)

This three-arm randomized phase 2 trial will enroll advanced clear cell RCC patients (all IMDC risk groups). Patients will be randomized 2:2:1 to either Arm A (fianlimab/ cemiplimab/ ipilimumab), Arm ...

Nashville, TX120 participantsBrian Rini

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NCT06966024Recruiting

Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

This is a multicenter clinical trial to evaluate the safety and preliminary activity of the selective general control nonderepressible 2 (GCN2) activator DCC-2812 as monotherapy in advanced/metastatic...

Nashville, TX60 participantsDeciphera Pharmaceuticals, LLC

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NCT05361720Recruiting

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

This phase II trial tests whether using genetic testing of tumor tissue to select the optimal treatment regimen works in treating patients with clear cell renal cell (kidney) cancer that has spread to...

Nashville, TX54 participantsVanderbilt-Ingram Cancer Center

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NCT06708949Recruiting

A Randomized Phase 2 Trial of Nivolumab, Relatlimab Plus Ipilimumab vs. Nivolumab Plus Ipilimumab in First-line Advanced Renal Cell Carcinoma (RCC)

This is a phase 2 stratified, randomized, multicenter, study investigating the efficacy of a triplet arm treating with nivolumab 480 mg every 4 weeks (Q4W), relatlimab 160 mg Q4W and ipilimumab 1 mg/k...

Nashville, TX15 participantsM.D. Anderson Cancer Center

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About Kidney Cancer Clinical Trials in Nashville

Kidney cancer, most commonly renal cell carcinoma, develops in the lining of the kidney tubules. It accounts for about 3-5% of all adult cancers. Treatment includes surgery, targeted therapy, immunotherapy, and radiation.

There are currently 6 kidney cancer clinical trials recruiting participants in Nashville, TX. These studies are seeking a combined 514 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Bristol-Myers Squibb, Brian Rini and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Kidney Cancer Clinical Trials in Nashville — FAQ

Are there kidney cancer clinical trials in Nashville?

Yes, there are 6 kidney cancer clinical trials currently recruiting in Nashville, TX. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Nashville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Nashville research site will contact you about next steps.

Are clinical trials in Nashville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Nashville studies also compensate for your time and travel.

What kidney cancer treatments are being tested?

The 6 active trials in Nashville are testing new therapies including novel drugs, biologics, and treatment approaches for kidney cancer.

Data updated July 13, 2026 from ClinicalTrials.gov