9 Brain Cancer Clinical Trials in New Haven, CT (2026)

Q: How do I join a clinical trial in New Haven?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the New Haven research site will contact you.

Recruiting Brain Cancer Studies in New Haven

NCT03970447Recruiting

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/III response adaptive randomization platform trial designed to evaluate multiple...

New Haven, CTPHASE22,250 participantsGlobal Coalition for Adaptive Research

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NCT05580562Recruiting

ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

This is a randomized, double-blind, placebo-controlled, parallel-group, international, Phase 3 study in patients with newly diagnosed H3 K27M-mutant diffuse glioma to assess whether treatment with ONC...

New Haven, CTPHASE3510 participantsChimerix

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NCT07215910Recruiting

Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

This phase III trial compares the effect of vorasidenib to placebo in combination with usual treatment, temozolomide, in treating patients with newly diagnosed grade 3 astrocytoma after radiation. Tem...

New Haven, CTPHASE3408 participantsAlliance for Clinical Trials in Oncology

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NCT05303519Recruiting

Safusidenib Phase 2 Study in IDH1 Mutant Glioma

This is a 2-part study. The purpose of Part 1 of the study is to evaluate the efficacy, safety, and pharmacokinetic (PK) characteristics of safusidenib in participants with recurrent/progressive IDH1-...

New Haven, CTPHASE3365 participantsNuvation Bio Inc.

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NCT04804644Recruiting

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the...

New Haven, CTPHASE3200 participantsNRG Oncology

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NCT06458712Recruiting

Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies

Open label, multi-centre, Phase Ia/b adaptive design study with an initial 2-stage Dose Escalation Phase followed by a Dose Expansion Phase....

New Haven, CTPHASE1180 participantsDuke Street Bio Ltd

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NCT07326566Recruiting

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

The purpose of this study is to see if combining silevertinib with temozolomide after surgery and radiotherapy helps treat newly diagnosed glioblastoma (GBM) better than using temozolomide alone in th...

New Haven, CTPHASE2162 participantsBlack Diamond Therapeutics, Inc.

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NCT05226494Recruiting

Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma

Glioblastoma is a highly aggressive and fatal form of primary malignant brain tumor with limited treatment options. fb-PMT affects a large group of cancer cell signaling pathways and thus may be effec...

New Haven, CTPHASE134 participantsNanoPharmaceuticals LLC

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NCT06860594Recruiting

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

This phase I trial tests the safety, side effects, and best dose of triapine in combination with radiation therapy in treating patients with glioblastoma or astrocytoma that has come back after a peri...

New Haven, CTPHASE130 participantsNational Cancer Institute (NCI)

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About Brain Cancer Clinical Trials in New Haven

Brain cancer includes tumors that originate in the brain (primary) or spread from other areas (metastatic). Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Treatment typically combines surgery, radiation, and chemotherapy, with immunotherapy trials underway.

There are currently 9 brain cancer clinical trials recruiting participants in New Haven, CT. These studies are seeking a combined 4,139 participants. Research is being sponsored by Global Coalition for Adaptive Research, Chimerix, Alliance for Clinical Trials in Oncology and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Brain Cancer Clinical Trials in New Haven — FAQ

Are there brain cancer clinical trials in New Haven?

Yes, there are 9 brain cancer clinical trials currently recruiting in New Haven, CT. Browse the studies on this page to find one that fits.

How do I join a clinical trial in New Haven?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the New Haven research site will contact you about next steps.

Are clinical trials in New Haven free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many New Haven studies also compensate for your time and travel.

What brain cancer treatments are being tested?

The 9 active trials in New Haven are testing new therapies including novel drugs, biologics, and treatment approaches for brain cancer.

Data updated July 17, 2026 from ClinicalTrials.gov