4 Knee Replacement Clinical Trials in New York, NY (2026)

Q: How do I join a clinical trial in New York?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you.

Recruiting Knee Replacement Studies in New York

NCT07548385Recruiting

Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN

This is a prospective, randomized study. The purpose of this study is to evaluate if the addition of Suzetrigine, a new pain medication, to well established peri-operative pain regimen used for total ...

New York, NYPHASE3235 participantsIcahn School of Medicine at Mount Sinai

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NCT05391828Recruiting

Persona MC vs PS RCT With ROSA

A randomized, controlled study comparing two total knee implant devices, Persona medial congruent (MC) vs posterior stabilized (PS). These surgeries will be performed using the ROSA robotic system. Pa...

New York, NYNA200 participantsNYU Langone Health

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NCT07864896Recruiting

Suzetrigine in TKA

Total knee replacements are among the most common and painful orthopedic procedures performed worldwide, often requiring intensive analgesia to support early ambulation and recovery. Despite widesprea...

New York, NYPHASE3148 participantsHospital for Special Surgery, New York

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NCT06896240Recruiting

Fiber Smoothie Supplement

This study aims to assess the feasibility of a 2-week dietary whole-food smoothie intervention and compare outcomes between two groups: patients that integrated a daily whole food plant-based smoothie...

New York, NYNA24 participantsHospital for Special Surgery, New York

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About Knee Replacement Clinical Trials in New York

Knee replacement surgery replaces weight-bearing surfaces of the knee joint with metal and plastic components to relieve pain and restore function. It is typically performed for severe osteoarthritis. Clinical trials investigate improved implant designs, surgical techniques, and pain management protocols.

There are currently 4 knee replacement clinical trials recruiting participants in New York, NY. These studies are seeking a combined 607 participants. Research is being sponsored by Icahn School of Medicine at Mount Sinai, NYU Langone Health, Hospital for Special Surgery, New York. Clinical trial participation is free and participants receive study-related medical care at no cost.

Knee Replacement Clinical Trials in New York — FAQ

Are there knee replacement clinical trials in New York?

Yes, there are 4 knee replacement clinical trials currently recruiting in New York, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in New York?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you about next steps.

Are clinical trials in New York free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many New York studies also compensate for your time and travel.

What knee replacement treatments are being tested?

The 4 active trials in New York are testing new therapies including novel drugs, biologics, and treatment approaches for knee replacement.

Data updated October 18, 2026 from ClinicalTrials.gov