Top Cities for Knee Replacement Clinical Trials
Knee Replacement clinical trials are recruiting across 4 cities. Here are the cities with the most active studies:
About Knee Replacement
Knee replacement surgery replaces weight-bearing surfaces of the knee joint with metal and plastic components to relieve pain and restore function. It is typically performed for severe osteoarthritis. Clinical trials investigate improved implant designs, surgical techniques, and pain management protocols.
Clinical trials are advancing new treatments for knee replacement. Currently, 1 studies are recruiting a combined 2,000 participants across the United States. Research is being conducted by 1 organizations including Regeneron Pharmaceuticals.
2026 Knee Replacement Research Landscape
As of March 2026, the knee replacement clinical trial landscape includes 1 actively recruiting studies across 4 cities in the United States. These studies are collectively seeking 2,000 participants, with an average enrollment target of 2,000 per study.
Research is being led by 1 organization, including Regeneron Pharmaceuticals.
Geographically, knee replacement trials are most concentrated in Englewood, Colorado (1 trial); Sarasota, Florida (1 trial); Tamarac, Florida (1 trial); Bellaire, Texas (1 trial).
Featured Knee Replacement Studies
Highlighted recruiting studies for knee replacement, selected by enrollment size and research scope.
REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults
This study is researching an experimental drug called REGN7508 (called "study drug"). The study is focused on adults undergoing elective, unilateral (one side) total knee replacement surgery. The aim of the study is to see how effective the study drug is at preventing venous thromboembolism (VTE) and other related diseases after total knee replacement surgery. The study is looking at several oth...
Frequently Asked Questions About Knee Replacement Clinical Trials
Are there knee replacement clinical trials near me?
Yes, there are 1 knee replacement clinical trials currently recruiting across 4+ cities in the United States, including Englewood, Colorado; Sarasota, Florida; Tamarac, Florida. Browse the studies above to find one at a location convenient for you.
How do I join a knee replacement clinical trial?
To join a knee replacement clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are knee replacement clinical trials free?
Yes, participation in knee replacement clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of knee replacement treatments are being studied?
Current knee replacement clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 1 research organizations.
Is it safe to participate in knee replacement clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 1, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 1, 2026 · Data from ClinicalTrials.gov