A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain
The main purpose of this study is to evaluate the efficacy and safety of retatrutide in relieving chronic low back pain in participants who have obesity or overweight. Participation in the study will ...
Nonpharmacologic Pain Management in FQHC Primary Care Clinics
The goal of this study is to improve pain management and reduce opioid reliance for patients with chronic back pain in Utah Federally-Qualified Health Centers (FQHCs). The study compares the effective...
Efficacy and Safety of Rexlemestrocel-L Combined With HA* in Participants With Moderate to Severe Chronic Low Back Pain
The primary purpose of this study is to evaluate the efficacy of rexlemestrocel-L+HA compared to control in reducing low back pain at 12 months post-treatment and safety of a single injection of rexle...
Development and Evaluation of Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain (CBOT-P)
The overarching goal of this study phase, Phase II component is to perform a randomized clinical trial of the refined Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of P...
Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.
This will be a placebo controlled, randomized, double-blind, comparative effectiveness study, in which we patients are enrolled during an emergency department (ED) visit for acute radicular low back p...
Top Cities for Back Pain Clinical Trials
Back Pain clinical trials are recruiting across 23 cities. Here are the cities with the most active studies:
About Back Pain
Chronic back pain is one of the most common reasons for missed work and doctor visits, affecting up to 80% of adults at some point. Causes range from muscle strain to disc problems and spinal conditions. Treatment includes physical therapy, medications, injections, and in some cases surgery.
Clinical trials are advancing new treatments for back pain. Currently, 5 studies are recruiting a combined 1,738 participants across the United States. Research is being conducted by 5 organizations including Eli Lilly and Company, University of Utah, Mesoblast, Ltd. and 2 others.
2026 Back Pain Research Landscape
As of March 2026, the back pain clinical trial landscape includes 5 actively recruiting studies across 23 cities in the United States. These studies are collectively seeking 1,738 participants, with an average enrollment target of 348 per study.
Research is being led by 5 different organizations, including Eli Lilly and Company, University of Utah, Mesoblast, Ltd., Evon Medics LLC, Montefiore Medical Center.
Geographically, back pain trials are most concentrated in San Diego, California (2 trials); Salt Lake City, Utah (2 trials); The Bronx, New York (2 trials); Chandler, Arizona (1 trial); Tucson, Arizona (1 trial) and 7 other cities.
Featured Back Pain Studies
Highlighted recruiting studies for back pain, selected by enrollment size and research scope.
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain
The main purpose of this study is to evaluate the efficacy and safety of retatrutide in relieving chronic low back pain in participants who have obesity or overweight. Participation in the study will last about 80 weeks.
Nonpharmacologic Pain Management in FQHC Primary Care Clinics
The goal of this study is to improve pain management and reduce opioid reliance for patients with chronic back pain in Utah Federally-Qualified Health Centers (FQHCs). The study compares the effectiveness of nonpharmacologic pain treatments using telehealth to overcome access barriers. We will use automated EHR reminders for electronic referral to teleconsult services. Our project tests adaptive t...
Efficacy and Safety of Rexlemestrocel-L Combined With HA* in Participants With Moderate to Severe Chronic Low Back Pain
The primary purpose of this study is to evaluate the efficacy of rexlemestrocel-L+HA compared to control in reducing low back pain at 12 months post-treatment and safety of a single injection of rexlemestrocel-L+HA injected into a lumbar intervertebral disc compared to control through 12 months post-treatment.
Frequently Asked Questions About Back Pain Clinical Trials
Are there back pain clinical trials near me?
Yes, there are 5 back pain clinical trials currently recruiting across 23+ cities in the United States, including San Diego, California; Salt Lake City, Utah; The Bronx, New York. Browse the studies above to find one at a location convenient for you.
How do I join a back pain clinical trial?
To join a back pain clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are back pain clinical trials free?
Yes, participation in back pain clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of back pain treatments are being studied?
Current back pain clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 5 research organizations.
Is it safe to participate in back pain clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 1, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 1, 2026 · Data from ClinicalTrials.gov