Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Spinal Stenosis Clinical Trials
Spinal Stenosis clinical trials are recruiting across 30 cities. Here are the cities with the most active studies:
Spinal Stenosis Trial Phases
10 research organizations are sponsoring spinal stenosis trials.
About Spinal Stenosis
Spinal stenosis is a narrowing of the spaces within the spine that can put pressure on the nerves traveling through it. It most commonly occurs in the lower back and neck. Treatment includes physical therapy, medications, steroid injections, and decompression surgery.
Clinical trials are advancing new treatments for spinal stenosis. Currently, 10 studies are recruiting a combined 10,373 participants across the United States. Research is being conducted by 10 organizations including Stryker Instruments, Columbia University, University of California, Los Angeles and 7 others.
2026 Spinal Stenosis Research Landscape
As of July 2026, the spinal stenosis clinical trial landscape includes 10 actively recruiting studies across 30 cities in the United States. These studies are collectively seeking 10,373 participants, with an average enrollment target of 1,037 per study.
The research spans multiple phases of development: 4 studies are in NA, 1 study is in PHASE4, 1 study is in PHASE2, 1 study is in EARLY_PHASE1. Early-phase studies suggest new therapeutic approaches are being explored for spinal stenosis.
Research is being led by 10 different organizations, including Stryker Instruments, Columbia University, University of California, Los Angeles, John O'Toole, Pacific Research Institute, and 5 others.
Geographically, spinal stenosis trials are most concentrated in New York, New York (2 trials); Athens, Alabama (1 trial); Bay Minette, Alabama (1 trial); Birmingham, Alabama (1 trial); Decatur, Alabama (1 trial) and 7 other cities.
Featured Spinal Stenosis Studies
Highlighted recruiting studies for spinal stenosis, selected by enrollment size and research scope.
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
This prospective longitudinal study will compare incidence rates of Medicare beneficiary surgical and minimally invasive intervention post index procedure, as well as harms associated with the MILD procedure, at 24 months post-treatment with MILD, tested against a control group of similar patients that have had a comparable procedure. This study will start with patients treated with a study proced...
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
Primary objective: To identify older adults with transthyretin cardiac amyloidosis (ATTR-CA) early in the course of the illness, at a time when disease modifying therapies are most effective. The specific aims of this epidemiologic investigation include: 1. To identify subjects with previous lumbar spinal stenosis (LSS) Surgery who have evidence of transthyretin (TTR) amyloid deposits in spinal...
Recording of Intraoperative Spinal Cord Stimulation and Monitoring
Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery...
Frequently Asked Questions About Spinal Stenosis Clinical Trials
Are there spinal stenosis clinical trials near me?
Yes, there are 10 spinal stenosis clinical trials currently recruiting across 30+ cities in the United States, including New York, New York; Athens, Alabama; Bay Minette, Alabama. Browse the studies above to find one at a location convenient for you.
How do I join a spinal stenosis clinical trial?
To join a spinal stenosis clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are spinal stenosis clinical trials free?
Yes, participation in spinal stenosis clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of spinal stenosis treatments are being studied?
Current spinal stenosis clinical trials are testing a range of approaches across NA (4 studies), PHASE4 (1 study), PHASE2 (1 study), EARLY_PHASE1 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 10 research organizations.
Is it safe to participate in spinal stenosis clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 17, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 17, 2026 · Data from ClinicalTrials.gov