Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Herniated Disc Clinical Trials
Herniated Disc clinical trials are recruiting across 14 cities. Here are the cities with the most active studies:
Herniated Disc Trial Phases
5 research organizations are sponsoring herniated disc trials.
About Herniated Disc
A herniated disc occurs when the soft center of a spinal disc pushes through a crack in the tougher exterior, potentially irritating nearby nerves. It most commonly affects the lower back (lumbar spine). Treatment includes physical therapy, pain medications, and surgery for persistent symptoms.
Clinical trials are advancing new treatments for herniated disc. Currently, 5 studies are recruiting a combined 455 participants across the United States. Research is being conducted by 5 organizations including University of Missouri-Columbia, University of California, San Diego, University of California, San Francisco and 2 others.
2026 Herniated Disc Research Landscape
As of July 2026, the herniated disc clinical trial landscape includes 5 actively recruiting studies across 14 cities in the United States. These studies are collectively seeking 455 participants, with an average enrollment target of 91 per study.
The research spans multiple phases of development: 2 studies are in PHASE4, 2 studies are in NA, 1 study is in EARLY_PHASE1. Early-phase studies suggest new therapeutic approaches are being explored for herniated disc.
Research is being led by 5 different organizations, including University of Missouri-Columbia, University of California, San Diego, University of California, San Francisco, Primus Pharmaceuticals, Columbia University.
Geographically, herniated disc trials are most concentrated in Columbia, Missouri (1 trial); La Jolla, California (1 trial); San Francisco, California (1 trial); Auburn, Alabama (1 trial); Valley Village, California (1 trial) and 7 other cities.
Featured Herniated Disc Studies
Highlighted recruiting studies for herniated disc, selected by enrollment size and research scope.
Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy
The purpose of this study is to determine a grading system for inflammation in lumbar disc herniation and which groups, if any, benefit most from the administration of an intra-operative epidural steroid.
Brain Mechanisms Supporting Cannabis-induced Pain Relief
Chronic low back pain is a common and disabling condition that affects millions of people in the United States. Many people with chronic low back pain do not get enough relief from current treatments. Cannabis may help reduce pain, but researchers do not fully understand how it affects the brain in people with chronic pain. The purpose of this study is to examine how inhaled cannabis changes brain...
Comparing Ultrasound-Guided Transgluteal Nerve Block to Standard Care
The goal of this clinical trial is to compare transgluteal sciatic nerve block to standard of care to treat sciatic back pain in adult patients who present to the emergency department. The main question it aims to answer is: Is a transgluteal sciatic nerve block better than standard of care in improving pain in ER patients with sciatic back pain? If there is a comparison group: Researchers will ...
Frequently Asked Questions About Herniated Disc Clinical Trials
Are there herniated disc clinical trials near me?
Yes, there are 5 herniated disc clinical trials currently recruiting across 14+ cities in the United States, including Columbia, Missouri; La Jolla, California; San Francisco, California. Browse the studies above to find one at a location convenient for you.
How do I join a herniated disc clinical trial?
To join a herniated disc clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are herniated disc clinical trials free?
Yes, participation in herniated disc clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of herniated disc treatments are being studied?
Current herniated disc clinical trials are testing a range of approaches across PHASE4 (2 studies), NA (2 studies), EARLY_PHASE1 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 5 research organizations.
Is it safe to participate in herniated disc clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 16, 2026 · Data from ClinicalTrials.gov