7 Myelofibrosis Clinical Trials in New York, NY (2026)

Q: How do I join a clinical trial in New York?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you.

Recruiting Myelofibrosis Studies in New York

NCT06343805Recruiting

A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

AJX-101 is a first-in-human (FIH), phase 1, non-randomized, multi-center, open-label clinical trial designed to investigate the safety, tolerability, pharmacokinetics (PK), clinical activity and chang...

New York, NYPHASE1256 participantsAjax Therapeutics, Inc.

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NCT06517875Recruiting

Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent Myelofibrosis

The purpose of this Phase 2 study is to evaluate the efficacy and safety of momelotinib (MMB) in combination with luspatercept (LUSPA) in participants with transfusion dependence (TD) primary myelofib...

New York, NYPHASE268 participantsGlaxoSmithKline

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NCT05980806Recruiting

A Study of Selinexor Monotherapy in Subjects with JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia

The main purpose of this study with corresponding optional expansion is to evaluate the efficacy of selinexor in JAKi-naïve participants with myelofibrosis (MF) and moderate thrombocytopenia based on ...

New York, NYPHASE258 participantsKaryopharm Therapeutics Inc

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NCT06773195Recruiting

A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis

The researchers are doing this study to find out whether the combination of ruxolitinib and ulixertinib is a safe and effective treatment for people with myelofibrosis. The researchers will test diffe...

New York, NYPHASE137 participantsMemorial Sloan Kettering Cancer Center

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NCT05423691Recruiting

Leading in MPNs Beyond Ruxolitinib in Combo With T-Regs

To assess the safety and tolerability of CK0804 as add-on therapy in participants with myelofibrosis, with suboptimal response to ruxolitinib...

New York, NYPHASE124 participantsCellenkos, Inc.

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NCT05714072Recruiting

A Study of Ruxolitinib in Combination With Abemaciclib for the Treatment of Myelofibrosis

The study is being done to see if the combination of ruxolitinib and abemaciclib is a safe and effective treatment for people with primary or post-polycythemia vera/essential thrombocythemia myelofibr...

New York, NYPHASE118 participantsMemorial Sloan Kettering Cancer Center

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NCT05835466Recruiting

Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)

This is an open label, phase II study to assess the efficacy, safety, and tolerability of Reparixin in patients with DIPSS intermediate-2, or high-risk primary myelofibrosis (PMF), post essential thro...

New York, NYPHASE210 participantsIcahn School of Medicine at Mount Sinai

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About Myelofibrosis Clinical Trials in New York

Myelofibrosis is a serious bone marrow disorder that disrupts normal blood cell production, leading to extensive scarring in the bone marrow. It can cause severe anemia, weakness, and an enlarged spleen. Treatment includes JAK inhibitors, blood transfusions, and stem cell transplant.

There are currently 7 myelofibrosis clinical trials recruiting participants in New York, NY. These studies are seeking a combined 471 participants. Research is being sponsored by Ajax Therapeutics, Inc., GlaxoSmithKline, Karyopharm Therapeutics Inc and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Myelofibrosis Clinical Trials in New York — FAQ

Are there myelofibrosis clinical trials in New York?

Yes, there are 7 myelofibrosis clinical trials currently recruiting in New York, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in New York?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you about next steps.

Are clinical trials in New York free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many New York studies also compensate for your time and travel.

What myelofibrosis treatments are being tested?

The 7 active trials in New York are testing new therapies including novel drugs, biologics, and treatment approaches for myelofibrosis.

Data updated October 14, 2026 from ClinicalTrials.gov