10 Schizophrenia Clinical Trials in New York, NY (2026)

Q: How do I join a clinical trial in New York?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you.

Recruiting Schizophrenia Studies in New York

NCT05509998Recruiting

Reducing the Duration of Untreated Psychosis in the United States: The Impact of Screening and Systematic Communication

The goal of this project is to investigate whether a systematic screening approach enhanced by an innovative model of communicating information about psychosis and treatment options to patients and fa...

New York, NYNA912 participantsIcahn School of Medicine at Mount Sinai

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NCT07184619Recruiting

Evenamide, a Glutamate Release Modulator, as Add-On to Standard of Care in Subjects With Documented Treatment-Resistant Schizophrenia

This is a prospective, 12-week, randomized, double-blind, placebo-controlled study, designed to evaluate the efficacy, safety, and tolerability of a dose of evenamide of 15 mg bid, compared to placebo...

New York, NYPHASE3400 participantsNewron Pharmaceuticals SPA

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NCT03817502Recruiting

Efficacy and Safety of Cariprazine in the Treatment of Adolescent Participants (13 to 17 Years of Age) With Schizophrenia

The purpose of this study is to evaluate the efficacy and safety of cariprazine in the treatment of schizophrenia in the adolescent population....

New York, NYPHASE3330 participantsGedeon Richter Plc.

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NCT05208190Recruiting

Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial

Two-hundred and eighty individuals with schizophrenia who have a recent history of violent acts will be randomized in this 2-arm, parallel-group, 24-week, open-label, 7-site clinical trial to examine ...

New York, NYPHASE4280 participantsNew York State Psychiatric Institute

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NCT07226895Recruiting

A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis

The goal of this clinical trial is to learn how tests undertaken by people at high risk of developing psychosis (aged 17 to 30 years old) change when those people are given the study drug MT1988 daily...

New York, NYPHASE1150 participantsMonument Therapeutics Limited

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NCT05805397Recruiting

Effectiveness of Motivation Skills Training (MST)

This study will take place at four outpatient clinics serving adults with serious mental illness. Informed consent will be obtained from N=80 individuals with a Diagnostic and Statistical Manual of Me...

New York, NYNA80 participantsColumbia University

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NCT05968560Recruiting

Telehealth Cognitive Behavioral Therapy for Youth at Risk for Psychosis

This study aims to evaluate the feasibility and effectiveness of telehealth interventions for individuals at clinical high risk for psychosis (CHR). Psychosis typically emerges during late adolescence...

New York, NYNA72 participantsIcahn School of Medicine at Mount Sinai

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NCT07434479Recruiting

A Virtual Reality Mindfulness Application for Aggression in Schizophrenia

The study investigates whether a virtual reality-based mindfulness based intervention can reduce impulsive aggression in individuals with schizophrenia or schizoaffective disorder. The primary goal is...

New York, NYNA58 participantsManhattan Psychiatric Center

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NCT05389787Recruiting

Impact of Cerebellar TMS on Brain and Cognitive Functions in Schizophrenia: a Pilot Study

This is a single-site, sham-controlled, randomized trial in a total of 40 subjects between ages 18 and 60 years with schizophrenia. This study will investigate the effects of 4-week rTMS treatment on ...

New York, NYNA40 participantsNorthwell Health

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NCT07423546Recruiting

A PET/MRI Study of Cobenfy on Dopamine Transmission in Schizophrenia

This is a single site clinical trial in which 12 participants with schizophrenia will be randomized to one of three doses of treatment with Cobenfy for 5 weeks. \[18F\]DOPA PET scans will be obtained ...

New York, NYPHASE112 participantsNew York State Psychiatric Institute

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About Schizophrenia Clinical Trials in New York

Schizophrenia is a chronic brain disorder affecting approximately 2.8 million US adults, characterized by hallucinations, delusions, disorganized thinking, and cognitive difficulties. While current treatments rely primarily on first- and second-generation antipsychotics (risperidone, olanzapine, clozapine), many patients experience incomplete symptom relief or significant side effects. Clinical trials are testing novel mechanisms including muscarinic receptor agonists (like KarXT/xanomeline-trospium), trace amine-associated receptor 1 (TAAR1) agonists, glutamate modulators, and long-acting injectable formulations. Treatment-resistant schizophrenia remains a major focus area, with trials seeking patients who have not adequately responded to standard antipsychotic therapy.

There are currently 10 schizophrenia clinical trials recruiting participants in New York, NY. These studies are seeking a combined 2,334 participants. Research is being sponsored by Icahn School of Medicine at Mount Sinai, Newron Pharmaceuticals SPA, Gedeon Richter Plc. and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Schizophrenia Clinical Trials in New York — FAQ

Are there schizophrenia clinical trials in New York?

Yes, there are 10 schizophrenia clinical trials currently recruiting in New York, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in New York?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you about next steps.

Are clinical trials in New York free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many New York studies also compensate for your time and travel.

What schizophrenia treatments are being tested?

The 10 active trials in New York are testing new therapies including novel drugs, biologics, and treatment approaches for schizophrenia.

Data updated October 21, 2026 from ClinicalTrials.gov